Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men

Detalhes bibliográficos
Autor(a) principal: Carrara,Rita C. V.
Data de Publicação: 2004
Outros Autores: Yamasaki,Rui, Mazucatto,Luís F., Veludo,Maria A. Llorach, Sartorato,Edi L., Pina-Neto,João M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002
Resumo: Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p).
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spelling Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile menmale infertilitycytogeneticsmicrodeletionsAZFmeiotic anomaliesClinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p).Sociedade Brasileira de Genética2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002Genetics and Molecular Biology v.27 n.4 2004reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572004000400002info:eu-repo/semantics/openAccessCarrara,Rita C. V.Yamasaki,RuiMazucatto,Luís F.Veludo,Maria A. LlorachSartorato,Edi L.Pina-Neto,João M.eng2005-01-14T00:00:00Zoai:scielo:S1415-47572004000400002Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2005-01-14T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
title Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
spellingShingle Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
Carrara,Rita C. V.
male infertility
cytogenetics
microdeletions
AZF
meiotic anomalies
title_short Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
title_full Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
title_fullStr Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
title_full_unstemmed Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
title_sort Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
author Carrara,Rita C. V.
author_facet Carrara,Rita C. V.
Yamasaki,Rui
Mazucatto,Luís F.
Veludo,Maria A. Llorach
Sartorato,Edi L.
Pina-Neto,João M.
author_role author
author2 Yamasaki,Rui
Mazucatto,Luís F.
Veludo,Maria A. Llorach
Sartorato,Edi L.
Pina-Neto,João M.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Carrara,Rita C. V.
Yamasaki,Rui
Mazucatto,Luís F.
Veludo,Maria A. Llorach
Sartorato,Edi L.
Pina-Neto,João M.
dc.subject.por.fl_str_mv male infertility
cytogenetics
microdeletions
AZF
meiotic anomalies
topic male infertility
cytogenetics
microdeletions
AZF
meiotic anomalies
description Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p).
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572004000400002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.27 n.4 2004
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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