Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Genetics and Molecular Biology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002 |
Resumo: | Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p). |
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Genetics and Molecular Biology |
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Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile menmale infertilitycytogeneticsmicrodeletionsAZFmeiotic anomaliesClinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p).Sociedade Brasileira de Genética2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002Genetics and Molecular Biology v.27 n.4 2004reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572004000400002info:eu-repo/semantics/openAccessCarrara,Rita C. V.Yamasaki,RuiMazucatto,Luís F.Veludo,Maria A. LlorachSartorato,Edi L.Pina-Neto,João M.eng2005-01-14T00:00:00Zoai:scielo:S1415-47572004000400002Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2005-01-14T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false |
dc.title.none.fl_str_mv |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
title |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
spellingShingle |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men Carrara,Rita C. V. male infertility cytogenetics microdeletions AZF meiotic anomalies |
title_short |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
title_full |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
title_fullStr |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
title_full_unstemmed |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
title_sort |
Somatic and germ cell cytogenetic studies and AZF microdeletion screening in infertile men |
author |
Carrara,Rita C. V. |
author_facet |
Carrara,Rita C. V. Yamasaki,Rui Mazucatto,Luís F. Veludo,Maria A. Llorach Sartorato,Edi L. Pina-Neto,João M. |
author_role |
author |
author2 |
Yamasaki,Rui Mazucatto,Luís F. Veludo,Maria A. Llorach Sartorato,Edi L. Pina-Neto,João M. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Carrara,Rita C. V. Yamasaki,Rui Mazucatto,Luís F. Veludo,Maria A. Llorach Sartorato,Edi L. Pina-Neto,João M. |
dc.subject.por.fl_str_mv |
male infertility cytogenetics microdeletions AZF meiotic anomalies |
topic |
male infertility cytogenetics microdeletions AZF meiotic anomalies |
description |
Clinical and cytogenetic studies were performed in 65 infertile individuals, and 56 of them were also screened for microdeletions in Yq11 (AZF region). Relevant environmental etiological factors were identified in 10 cases (15.4%). Sertoli-cell-only syndrome was diagnosed in six patients (9,2%). Karyotype abnormalities were detected in six individuals, and five other patients presented desynapsis of bivalents in meiosis. Three out of the 56 patients studied were carriers of microdeletions in the AZF region, one of them also presenting a chromosomal mosaicism for an extra i(22p). |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1415-47572004000400002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
Genetics and Molecular Biology v.27 n.4 2004 reponame:Genetics and Molecular Biology instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
instname_str |
Sociedade Brasileira de Genética (SBG) |
instacron_str |
SBG |
institution |
SBG |
reponame_str |
Genetics and Molecular Biology |
collection |
Genetics and Molecular Biology |
repository.name.fl_str_mv |
Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG) |
repository.mail.fl_str_mv |
||editor@gmb.org.br |
_version_ |
1752122379080826880 |