Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Genetics and Molecular Biology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024 |
Resumo: | The biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes. |
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Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocyteschromosomal aberrationshuman lymphocytesmicrowavesThe biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes.Sociedade Brasileira de Genética2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024Genetics and Molecular Biology v.27 n.3 2004reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572004000300024info:eu-repo/semantics/openAccessFigueiredo,André B.S.Alves,Rex N.Ramalho,Adriana T.eng2004-09-01T00:00:00Zoai:scielo:S1415-47572004000300024Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2004-09-01T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false |
dc.title.none.fl_str_mv |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
title |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
spellingShingle |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes Figueiredo,André B.S. chromosomal aberrations human lymphocytes microwaves |
title_short |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
title_full |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
title_fullStr |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
title_full_unstemmed |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
title_sort |
Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes |
author |
Figueiredo,André B.S. |
author_facet |
Figueiredo,André B.S. Alves,Rex N. Ramalho,Adriana T. |
author_role |
author |
author2 |
Alves,Rex N. Ramalho,Adriana T. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Figueiredo,André B.S. Alves,Rex N. Ramalho,Adriana T. |
dc.subject.por.fl_str_mv |
chromosomal aberrations human lymphocytes microwaves |
topic |
chromosomal aberrations human lymphocytes microwaves |
description |
The biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1415-47572004000300024 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
Genetics and Molecular Biology v.27 n.3 2004 reponame:Genetics and Molecular Biology instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
instname_str |
Sociedade Brasileira de Genética (SBG) |
instacron_str |
SBG |
institution |
SBG |
reponame_str |
Genetics and Molecular Biology |
collection |
Genetics and Molecular Biology |
repository.name.fl_str_mv |
Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG) |
repository.mail.fl_str_mv |
||editor@gmb.org.br |
_version_ |
1752122379077681152 |