Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes

Detalhes bibliográficos
Autor(a) principal: Figueiredo,André B.S.
Data de Publicação: 2004
Outros Autores: Alves,Rex N., Ramalho,Adriana T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024
Resumo: The biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes.
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spelling Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocyteschromosomal aberrationshuman lymphocytesmicrowavesThe biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes.Sociedade Brasileira de Genética2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024Genetics and Molecular Biology v.27 n.3 2004reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572004000300024info:eu-repo/semantics/openAccessFigueiredo,André B.S.Alves,Rex N.Ramalho,Adriana T.eng2004-09-01T00:00:00Zoai:scielo:S1415-47572004000300024Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2004-09-01T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
title Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
spellingShingle Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
Figueiredo,André B.S.
chromosomal aberrations
human lymphocytes
microwaves
title_short Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
title_full Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
title_fullStr Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
title_full_unstemmed Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
title_sort Cytogenetic analysis of the effects of 2.5 and 10.5 GHz microwaves on human lymphocytes
author Figueiredo,André B.S.
author_facet Figueiredo,André B.S.
Alves,Rex N.
Ramalho,Adriana T.
author_role author
author2 Alves,Rex N.
Ramalho,Adriana T.
author2_role author
author
dc.contributor.author.fl_str_mv Figueiredo,André B.S.
Alves,Rex N.
Ramalho,Adriana T.
dc.subject.por.fl_str_mv chromosomal aberrations
human lymphocytes
microwaves
topic chromosomal aberrations
human lymphocytes
microwaves
description The biological effects of microwaves on living organisms remain highly controversial. Although some reports have suggested that microwaves may be directly or indirectly genotoxic, a direct action is unlikely because the low energy of microwave photons makes them unable to cause single-strand breaks in DNA. In this work, we examined the possible clastogenic properties of microwaves (2.5 and 10.5 GHz) on blood lymphocytes in vitro by monitoring the frequency of chromosomal aberrations. We also investigated whether blood cells showed increased radiosensitivity or radioresistance when pretreated with the microwaves and then irradiated with gamma radiation. There was no significant difference in the frequency of chromosomal aberrations between cells which had or had not been treated with microwaves. Control cells had a mean frequency of 0.013 aberrations per cell compared to 0.010 and 0.011 aberrations per cell in the microwave-exposed samples. Nor was there any alteration in the radiosensitivity of cells pretreated with microwaves. Gamma irradiated cells showed a mean frequency of 0.279 aberrations per cell compared to 0.343 and 0.310 aberrations per cell in samples pretreated with microwaves. However, cell mortality increased markedly after exposure to microwaves. The results suggest that microwaves do not interact directly or indirectly with chromosomes, although they may target other cell structures, such as cell membranes.
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300024
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572004000300024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.27 n.3 2004
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
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