In search of essentiality: Mollicute-specific genes shared by twelve genomes

Detalhes bibliográficos
Autor(a) principal: Souza,Rangel Celso
Data de Publicação: 2007
Outros Autores: Almeida,Darcy Fontoura de, Zaha,Arnaldo, Morais,David Anderson de Lima, Vasconcelos,Ana Tereza Ribeiro de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200002
Resumo: Mollicutes are cell wall-less bacteria with a genome characterized by its small size. Chromosomal rearrangements help these organisms evade host immune surveillance and hence cause disease. Our goal was to determine genes shared by Mollicutes genomes using the bidirectional best hit methodology. The twelve studied Mollicutes share 210 genes, most of which (> 60%) fall into the following COG categories: translation, ribosomal structure and biogenesis; DNA replication, recombination and repair; nucleotide transport and metabolism and energy production and conversion. Thirty Mollicute-specific genes were identified, 22 of them previously described as essential genes in Mycoplasma genitalium.
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spelling In search of essentiality: Mollicute-specific genes shared by twelve genomesmollicutescomparative genomicssyntenybidirectional best hitMollicutes are cell wall-less bacteria with a genome characterized by its small size. Chromosomal rearrangements help these organisms evade host immune surveillance and hence cause disease. Our goal was to determine genes shared by Mollicutes genomes using the bidirectional best hit methodology. The twelve studied Mollicutes share 210 genes, most of which (> 60%) fall into the following COG categories: translation, ribosomal structure and biogenesis; DNA replication, recombination and repair; nucleotide transport and metabolism and energy production and conversion. Thirty Mollicute-specific genes were identified, 22 of them previously described as essential genes in Mycoplasma genitalium.Sociedade Brasileira de Genética2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200002Genetics and Molecular Biology v.30 n.1 suppl.0 2007reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572007000200002info:eu-repo/semantics/openAccessSouza,Rangel CelsoAlmeida,Darcy Fontoura deZaha,ArnaldoMorais,David Anderson de LimaVasconcelos,Ana Tereza Ribeiro deeng2007-05-14T00:00:00Zoai:scielo:S1415-47572007000200002Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2007-05-14T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv In search of essentiality: Mollicute-specific genes shared by twelve genomes
title In search of essentiality: Mollicute-specific genes shared by twelve genomes
spellingShingle In search of essentiality: Mollicute-specific genes shared by twelve genomes
Souza,Rangel Celso
mollicutes
comparative genomics
synteny
bidirectional best hit
title_short In search of essentiality: Mollicute-specific genes shared by twelve genomes
title_full In search of essentiality: Mollicute-specific genes shared by twelve genomes
title_fullStr In search of essentiality: Mollicute-specific genes shared by twelve genomes
title_full_unstemmed In search of essentiality: Mollicute-specific genes shared by twelve genomes
title_sort In search of essentiality: Mollicute-specific genes shared by twelve genomes
author Souza,Rangel Celso
author_facet Souza,Rangel Celso
Almeida,Darcy Fontoura de
Zaha,Arnaldo
Morais,David Anderson de Lima
Vasconcelos,Ana Tereza Ribeiro de
author_role author
author2 Almeida,Darcy Fontoura de
Zaha,Arnaldo
Morais,David Anderson de Lima
Vasconcelos,Ana Tereza Ribeiro de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Souza,Rangel Celso
Almeida,Darcy Fontoura de
Zaha,Arnaldo
Morais,David Anderson de Lima
Vasconcelos,Ana Tereza Ribeiro de
dc.subject.por.fl_str_mv mollicutes
comparative genomics
synteny
bidirectional best hit
topic mollicutes
comparative genomics
synteny
bidirectional best hit
description Mollicutes are cell wall-less bacteria with a genome characterized by its small size. Chromosomal rearrangements help these organisms evade host immune surveillance and hence cause disease. Our goal was to determine genes shared by Mollicutes genomes using the bidirectional best hit methodology. The twelve studied Mollicutes share 210 genes, most of which (> 60%) fall into the following COG categories: translation, ribosomal structure and biogenesis; DNA replication, recombination and repair; nucleotide transport and metabolism and energy production and conversion. Thirty Mollicute-specific genes were identified, 22 of them previously described as essential genes in Mycoplasma genitalium.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572007000200002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.30 n.1 suppl.0 2007
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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