Resveratrol effects in bladder cancer: A mini review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Genetics and Molecular Biology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000100107 |
Resumo: | Abstract Bladder cancer has a high incidence worldwide and is the most common genitourinary cancer. The treatment of bladder cancer involves surgery and chemotherapy; however high failure rates and toxicity are observed. In this context, the search of new drugs aiming a more effective treatment is extremely necessary. Natural products are an important source of compounds with antiproliferative effects. Resveratrol is a naturally occurring plant polyphenol whose anticancer activity has been demonstrated in different types of cancer. This review summarizes the in vitro and in vivo studies using models of bladder cancer treated with resveratrol and discusses its different mechanisms of action. |
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Genetics and Molecular Biology |
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Resveratrol effects in bladder cancer: A mini reviewApoptosisbladder cancercell cycle arrestcell signallingresveratrolAbstract Bladder cancer has a high incidence worldwide and is the most common genitourinary cancer. The treatment of bladder cancer involves surgery and chemotherapy; however high failure rates and toxicity are observed. In this context, the search of new drugs aiming a more effective treatment is extremely necessary. Natural products are an important source of compounds with antiproliferative effects. Resveratrol is a naturally occurring plant polyphenol whose anticancer activity has been demonstrated in different types of cancer. This review summarizes the in vitro and in vivo studies using models of bladder cancer treated with resveratrol and discusses its different mechanisms of action.Sociedade Brasileira de Genética2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000100107Genetics and Molecular Biology v.44 n.1 2021reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/1678-4685-gmb-2020-0371info:eu-repo/semantics/openAccessAlmeida,Tamires CunhaSilva,Glenda Nicioli daeng2021-03-19T00:00:00Zoai:scielo:S1415-47572021000100107Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2021-03-19T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false |
dc.title.none.fl_str_mv |
Resveratrol effects in bladder cancer: A mini review |
title |
Resveratrol effects in bladder cancer: A mini review |
spellingShingle |
Resveratrol effects in bladder cancer: A mini review Almeida,Tamires Cunha Apoptosis bladder cancer cell cycle arrest cell signalling resveratrol |
title_short |
Resveratrol effects in bladder cancer: A mini review |
title_full |
Resveratrol effects in bladder cancer: A mini review |
title_fullStr |
Resveratrol effects in bladder cancer: A mini review |
title_full_unstemmed |
Resveratrol effects in bladder cancer: A mini review |
title_sort |
Resveratrol effects in bladder cancer: A mini review |
author |
Almeida,Tamires Cunha |
author_facet |
Almeida,Tamires Cunha Silva,Glenda Nicioli da |
author_role |
author |
author2 |
Silva,Glenda Nicioli da |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Almeida,Tamires Cunha Silva,Glenda Nicioli da |
dc.subject.por.fl_str_mv |
Apoptosis bladder cancer cell cycle arrest cell signalling resveratrol |
topic |
Apoptosis bladder cancer cell cycle arrest cell signalling resveratrol |
description |
Abstract Bladder cancer has a high incidence worldwide and is the most common genitourinary cancer. The treatment of bladder cancer involves surgery and chemotherapy; however high failure rates and toxicity are observed. In this context, the search of new drugs aiming a more effective treatment is extremely necessary. Natural products are an important source of compounds with antiproliferative effects. Resveratrol is a naturally occurring plant polyphenol whose anticancer activity has been demonstrated in different types of cancer. This review summarizes the in vitro and in vivo studies using models of bladder cancer treated with resveratrol and discusses its different mechanisms of action. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000100107 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572021000100107 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1678-4685-gmb-2020-0371 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
Genetics and Molecular Biology v.44 n.1 2021 reponame:Genetics and Molecular Biology instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
instname_str |
Sociedade Brasileira de Genética (SBG) |
instacron_str |
SBG |
institution |
SBG |
reponame_str |
Genetics and Molecular Biology |
collection |
Genetics and Molecular Biology |
repository.name.fl_str_mv |
Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG) |
repository.mail.fl_str_mv |
||editor@gmb.org.br |
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1752122390185246720 |