Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes

Bibliographic Details
Main Author: Loreto,Elgion Lúcio Silva
Publication Date: 2007
Other Authors: Ortiz,Mauro Freitas, Porto,Jorge Ivan Rebelo
Format: Article
Language: eng
Source: Genetics and Molecular Biology
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200017
Summary: We have analyzed the sequenced genomes of three strains of Mycoplasma hyopneumoniae and one strain of M. synoviae, and have found three and two different transposable element families, respectively in each species. In M. hyopneumoniae, the Insertion Sequences of the IS4 family is represented by ISMHp1, a putatively active element. The IS3 family is represented by several degenerated sequences. A third element called tMH was found, which shows some characteristics reminiscent of retrotransposons. In M. synoviae, three different possibly active IS4 elements are present (ISMHp1-like; ISMs1 and IS1634-like elements). The IS30 family is represented by the degenerated IS1630-like element. The IS1634-like element is shown to be involved in chromosomal rearrangements and horizontal gene transfer (HGT). The ISMHp1-like element is shown to relate to the HGT of a 25-kb region from M. gallisepticum to M. synoviae. The fractions of these genomes that correspond to mobile elements varied from 1.35 to 3.13% in M. hyopneumonia strains and was 2.08% in M. synoviae. Although these species possess reduced genomes, they maintain mobile elements, perhaps as a mechanism for genetic variability production.
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spelling Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomesinsertion sequencesISmollicuteshorizontal gene transfermycoplasmaWe have analyzed the sequenced genomes of three strains of Mycoplasma hyopneumoniae and one strain of M. synoviae, and have found three and two different transposable element families, respectively in each species. In M. hyopneumoniae, the Insertion Sequences of the IS4 family is represented by ISMHp1, a putatively active element. The IS3 family is represented by several degenerated sequences. A third element called tMH was found, which shows some characteristics reminiscent of retrotransposons. In M. synoviae, three different possibly active IS4 elements are present (ISMHp1-like; ISMs1 and IS1634-like elements). The IS30 family is represented by the degenerated IS1630-like element. The IS1634-like element is shown to be involved in chromosomal rearrangements and horizontal gene transfer (HGT). The ISMHp1-like element is shown to relate to the HGT of a 25-kb region from M. gallisepticum to M. synoviae. The fractions of these genomes that correspond to mobile elements varied from 1.35 to 3.13% in M. hyopneumonia strains and was 2.08% in M. synoviae. Although these species possess reduced genomes, they maintain mobile elements, perhaps as a mechanism for genetic variability production.Sociedade Brasileira de Genética2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200017Genetics and Molecular Biology v.30 n.1 suppl.0 2007reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572007000200017info:eu-repo/semantics/openAccessLoreto,Elgion Lúcio SilvaOrtiz,Mauro FreitasPorto,Jorge Ivan Rebeloeng2007-05-14T00:00:00Zoai:scielo:S1415-47572007000200017Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2007-05-14T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
title Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
spellingShingle Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
Loreto,Elgion Lúcio Silva
insertion sequences
IS
mollicutes
horizontal gene transfer
mycoplasma
title_short Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
title_full Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
title_fullStr Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
title_full_unstemmed Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
title_sort Insertion sequences as variability generators in the Mycoplasma hyopneumoniae and M. synoviae genomes
author Loreto,Elgion Lúcio Silva
author_facet Loreto,Elgion Lúcio Silva
Ortiz,Mauro Freitas
Porto,Jorge Ivan Rebelo
author_role author
author2 Ortiz,Mauro Freitas
Porto,Jorge Ivan Rebelo
author2_role author
author
dc.contributor.author.fl_str_mv Loreto,Elgion Lúcio Silva
Ortiz,Mauro Freitas
Porto,Jorge Ivan Rebelo
dc.subject.por.fl_str_mv insertion sequences
IS
mollicutes
horizontal gene transfer
mycoplasma
topic insertion sequences
IS
mollicutes
horizontal gene transfer
mycoplasma
description We have analyzed the sequenced genomes of three strains of Mycoplasma hyopneumoniae and one strain of M. synoviae, and have found three and two different transposable element families, respectively in each species. In M. hyopneumoniae, the Insertion Sequences of the IS4 family is represented by ISMHp1, a putatively active element. The IS3 family is represented by several degenerated sequences. A third element called tMH was found, which shows some characteristics reminiscent of retrotransposons. In M. synoviae, three different possibly active IS4 elements are present (ISMHp1-like; ISMs1 and IS1634-like elements). The IS30 family is represented by the degenerated IS1630-like element. The IS1634-like element is shown to be involved in chromosomal rearrangements and horizontal gene transfer (HGT). The ISMHp1-like element is shown to relate to the HGT of a 25-kb region from M. gallisepticum to M. synoviae. The fractions of these genomes that correspond to mobile elements varied from 1.35 to 3.13% in M. hyopneumonia strains and was 2.08% in M. synoviae. Although these species possess reduced genomes, they maintain mobile elements, perhaps as a mechanism for genetic variability production.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572007000200017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572007000200017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.30 n.1 suppl.0 2007
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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