Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)

Detalhes bibliográficos
Autor(a) principal: Javed,Ruheena
Data de Publicação: 2011
Outros Autores: Gautam,Sanjeev K., Vijh,Ramesh K., Tantia,Madhu S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400011
Resumo: More than 40 million households in India depend at least partially on livestock production. Buffaloes are one of the major milk producers in India. The prolactin receptor (PRLR) gene and peroxisome proliferators activated receptor-γ coactivator 1-alpha (PPARGC1A) gene are reportedly associated with milk protein and milk fat yields in Bos taurus. In this study, we sequenced the PRLR and PPARGC1A genes in the water buffalo Bubalus bubalis. The PRLR and PPARGC1A genes coded for 581 and 819 amino acids, respectively. The B. bubalis PRLR gene differed from the corresponding Bos taurus at 21 positions and four differences with an additional arginine at position 620 in the PPARGC1A gene were found in the amino acid sequence. All of the changes were confirmed by cDNA sequencing. Twelve buffalo-specific single nucleotide polymorphisms (SNPs) were identified in both genes, with five of them being non-synonymous.
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spelling Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)Bubalus bubalisbuffaloPRLR genePPARGC1A geneMore than 40 million households in India depend at least partially on livestock production. Buffaloes are one of the major milk producers in India. The prolactin receptor (PRLR) gene and peroxisome proliferators activated receptor-γ coactivator 1-alpha (PPARGC1A) gene are reportedly associated with milk protein and milk fat yields in Bos taurus. In this study, we sequenced the PRLR and PPARGC1A genes in the water buffalo Bubalus bubalis. The PRLR and PPARGC1A genes coded for 581 and 819 amino acids, respectively. The B. bubalis PRLR gene differed from the corresponding Bos taurus at 21 positions and four differences with an additional arginine at position 620 in the PPARGC1A gene were found in the amino acid sequence. All of the changes were confirmed by cDNA sequencing. Twelve buffalo-specific single nucleotide polymorphisms (SNPs) were identified in both genes, with five of them being non-synonymous.Sociedade Brasileira de Genética2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400011Genetics and Molecular Biology v.34 n.4 2011reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572011005000037info:eu-repo/semantics/openAccessJaved,RuheenaGautam,Sanjeev K.Vijh,Ramesh K.Tantia,Madhu S.eng2011-11-11T00:00:00Zoai:scielo:S1415-47572011000400011Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2011-11-11T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
title Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
spellingShingle Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
Javed,Ruheena
Bubalus bubalis
buffalo
PRLR gene
PPARGC1A gene
title_short Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
title_full Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
title_fullStr Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
title_full_unstemmed Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
title_sort Characterization of PRLR and PPARGC1A genes in buffalo (Bubalus bubalis)
author Javed,Ruheena
author_facet Javed,Ruheena
Gautam,Sanjeev K.
Vijh,Ramesh K.
Tantia,Madhu S.
author_role author
author2 Gautam,Sanjeev K.
Vijh,Ramesh K.
Tantia,Madhu S.
author2_role author
author
author
dc.contributor.author.fl_str_mv Javed,Ruheena
Gautam,Sanjeev K.
Vijh,Ramesh K.
Tantia,Madhu S.
dc.subject.por.fl_str_mv Bubalus bubalis
buffalo
PRLR gene
PPARGC1A gene
topic Bubalus bubalis
buffalo
PRLR gene
PPARGC1A gene
description More than 40 million households in India depend at least partially on livestock production. Buffaloes are one of the major milk producers in India. The prolactin receptor (PRLR) gene and peroxisome proliferators activated receptor-γ coactivator 1-alpha (PPARGC1A) gene are reportedly associated with milk protein and milk fat yields in Bos taurus. In this study, we sequenced the PRLR and PPARGC1A genes in the water buffalo Bubalus bubalis. The PRLR and PPARGC1A genes coded for 581 and 819 amino acids, respectively. The B. bubalis PRLR gene differed from the corresponding Bos taurus at 21 positions and four differences with an additional arginine at position 620 in the PPARGC1A gene were found in the amino acid sequence. All of the changes were confirmed by cDNA sequencing. Twelve buffalo-specific single nucleotide polymorphisms (SNPs) were identified in both genes, with five of them being non-synonymous.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000400011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572011005000037
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.34 n.4 2011
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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