Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Genetics and Molecular Biology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400011 |
Resumo: | ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia. |
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Genetics and Molecular Biology |
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Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studiesschizophreniaERBB3 geneERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia.Sociedade Brasileira de Genética2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400011Genetics and Molecular Biology v.32 n.4 2009reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572009005000088info:eu-repo/semantics/openAccessLi,DaweiHe,GuangXu,YifengDuan,YunGu,NiufanLi,XingwangShi,YongyongQin,WeiFeng,GuoyinHe,Lineng2009-11-17T00:00:00Zoai:scielo:S1415-47572009000400011Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2009-11-17T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false |
dc.title.none.fl_str_mv |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
title |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
spellingShingle |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies Li,Dawei schizophrenia ERBB3 gene |
title_short |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
title_full |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
title_fullStr |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
title_full_unstemmed |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
title_sort |
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: results from case-control and family-based studies |
author |
Li,Dawei |
author_facet |
Li,Dawei He,Guang Xu,Yifeng Duan,Yun Gu,Niufan Li,Xingwang Shi,Yongyong Qin,Wei Feng,Guoyin He,Lin |
author_role |
author |
author2 |
He,Guang Xu,Yifeng Duan,Yun Gu,Niufan Li,Xingwang Shi,Yongyong Qin,Wei Feng,Guoyin He,Lin |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Li,Dawei He,Guang Xu,Yifeng Duan,Yun Gu,Niufan Li,Xingwang Shi,Yongyong Qin,Wei Feng,Guoyin He,Lin |
dc.subject.por.fl_str_mv |
schizophrenia ERBB3 gene |
topic |
schizophrenia ERBB3 gene |
description |
ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1415-47572009005000088 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
dc.source.none.fl_str_mv |
Genetics and Molecular Biology v.32 n.4 2009 reponame:Genetics and Molecular Biology instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
instname_str |
Sociedade Brasileira de Genética (SBG) |
instacron_str |
SBG |
institution |
SBG |
reponame_str |
Genetics and Molecular Biology |
collection |
Genetics and Molecular Biology |
repository.name.fl_str_mv |
Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG) |
repository.mail.fl_str_mv |
||editor@gmb.org.br |
_version_ |
1752122382380695552 |