Evaluation of genotoxicity through micronuclei test in workers of car and battery repair garages

• Autor(a) principal: Martino-Roth,M.G.
• Data de Publicação: 2002
• Outros Autores: Viégas,J., Amaral,M., Oliveira,L., Ferreira,F.L.S., Erdtmann,B.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Genetics and Molecular Biology
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572002000400021
• topic: micronucleus test; occupational exposure

In this study, the micronuclei test (MNT) was applied in exfoliated cells of buccal mucosa, in order to evaluate the genotoxic risk associated with occupational exposure of mechanics, storage battery renovation workers, and car painters. For each individual, 3000 exfoliated buccal cells were analyzed. There was a significantly higher frequency of micronucleated cells (MNC) in the exposed workers than in controls. Smoking and drinking habits, age, and working time did not represent significant factors in terms of increasing the production of micronuclei (MN), when the control and the exposed groups were compared. These results allowed to conclude that the studied individuals belong to a risk group and should periodically undergo biological monitoring and proper care.