Analysis of the QT interval prolongation and pharmaceuticals in elderly patients in ambulatory care

• Autor(a) principal: Prado,Nereida Ferraz Vieira do
• Data de Publicação: 2017
• Outros Autores: Turini,Ana Elize, Bollis,Giuliana Tonani, Linhares,Fernanda, Tieppo,Alessandra, Devens,Lívia Terezinha, Morelato,Renato Lírio
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Geriatrics, Gerontology and Aging (Online)
• Texto Completo: https://ggaging.com/details/429
• topic: Long QT syndrome; Pharmaceutical preparations; Elderly people.

<p><b>OBJECTIVES:</b> The objective of this study was to evaluate the frequency of long QT syndrome (LQTS) in the electrocardiographic tracing of elderly people and the concomitant use of drugs that can aggravate this condition.<br> <b>METHODS:</b> This is a crosssectional, observational study of elderly patients in outpatient services at Hospital Santa Casa de Misericórdia de Vitória, over a six-month period.<br> <b>RESULTS:</b> A total of 163 patients with 75 ± 8 (60–94) years of age, 60.7% (n = 99) of whom were female, participated in the study. Of the total number of patients, 33.1% (n = 54) were regularly taking at least one pharmaceutical that increased the risk of QTc prolongation; 34 patients (20.9%) had prolonged QTc and 15 (9,2%) had at-risk QTc. Of these patients with at-risk QTc, 4 (23.4%) were using at least 1 1 pharmaceutical that increases the risk of QT prolongation (p = 0.07).<br> <b>CONCLUSION:</b> In this sample, a high frequency of LQTS was observed, as well as the use of pharmaceuticals that potentially cause LQTS and arrhythmias.</p>