Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV

Detalhes bibliográficos
Autor(a) principal: Campos,Angélica Cristine de Almeida
Data de Publicação: 2007
Outros Autores: Durigon,Edison Luiz, Leal,Andréa Lima, Silva,Tereza Souza, Bosso,Patrícia Alves Ramos, Moraes,Claudia Trigo Pedroso, Oliveira,Danielle Bruna Leal, Lima,Hildener Nogueira, Vieira,Sandra Elisabete, Botosso,Viviane Fongaro, Zanotto,Paolo Marinho de Andrade, Stewien,Klaus Eberhard
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300005
Resumo: The Human Respiratory Syncytial Virus (HRSV), isolated in 1955, is the main cause of hospitalization of babies and infants with respiratory illness. Several studies have been conducted worldwide aiming the development of a safe and effective vaccine against HRSV. The G2 region of glycoprotein G is used as genotyping default. In the present study, we performed a phylogenetic analysis of G protein and a comparative study between G2 region and ectodomain of attachment glycoprotein. Fifty-three nasal swab samples from children less than 5 years old and presenting symptoms of acute respiratory illness, assisted at the University Hospital (UH) of University of Sao Paulo (USP) in 2004, were submitted to sequencing by PCR and compared with GenBank sequences. We concluded that the G2 region is adequate for HRSV genotyping.
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spelling Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSVHuman Respiratory Syncytial VirusG GlycoproteinG2 RegionPhylogenetic AnalysisThe Human Respiratory Syncytial Virus (HRSV), isolated in 1955, is the main cause of hospitalization of babies and infants with respiratory illness. Several studies have been conducted worldwide aiming the development of a safe and effective vaccine against HRSV. The G2 region of glycoprotein G is used as genotyping default. In the present study, we performed a phylogenetic analysis of G protein and a comparative study between G2 region and ectodomain of attachment glycoprotein. Fifty-three nasal swab samples from children less than 5 years old and presenting symptoms of acute respiratory illness, assisted at the University Hospital (UH) of University of Sao Paulo (USP) in 2004, were submitted to sequencing by PCR and compared with GenBank sequences. We concluded that the G2 region is adequate for HRSV genotyping.Sociedade Brasileira de Microbiologia2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300005Brazilian Journal of Microbiology v.38 n.3 2007reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822007000300005info:eu-repo/semantics/openAccessCampos,Angélica Cristine de AlmeidaDurigon,Edison LuizLeal,Andréa LimaSilva,Tereza SouzaBosso,Patrícia Alves RamosMoraes,Claudia Trigo PedrosoOliveira,Danielle Bruna LealLima,Hildener NogueiraVieira,Sandra ElisabeteBotosso,Viviane FongaroZanotto,Paolo Marinho de AndradeStewien,Klaus Eberhardeng2007-10-17T00:00:00Zoai:scielo:S1517-83822007000300005Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2007-10-17T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
title Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
spellingShingle Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
Campos,Angélica Cristine de Almeida
Human Respiratory Syncytial Virus
G Glycoprotein
G2 Region
Phylogenetic Analysis
title_short Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
title_full Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
title_fullStr Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
title_full_unstemmed Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
title_sort Comparison between ectodomain and G2 region of G glycoprotein for genotyping of HRSV
author Campos,Angélica Cristine de Almeida
author_facet Campos,Angélica Cristine de Almeida
Durigon,Edison Luiz
Leal,Andréa Lima
Silva,Tereza Souza
Bosso,Patrícia Alves Ramos
Moraes,Claudia Trigo Pedroso
Oliveira,Danielle Bruna Leal
Lima,Hildener Nogueira
Vieira,Sandra Elisabete
Botosso,Viviane Fongaro
Zanotto,Paolo Marinho de Andrade
Stewien,Klaus Eberhard
author_role author
author2 Durigon,Edison Luiz
Leal,Andréa Lima
Silva,Tereza Souza
Bosso,Patrícia Alves Ramos
Moraes,Claudia Trigo Pedroso
Oliveira,Danielle Bruna Leal
Lima,Hildener Nogueira
Vieira,Sandra Elisabete
Botosso,Viviane Fongaro
Zanotto,Paolo Marinho de Andrade
Stewien,Klaus Eberhard
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Campos,Angélica Cristine de Almeida
Durigon,Edison Luiz
Leal,Andréa Lima
Silva,Tereza Souza
Bosso,Patrícia Alves Ramos
Moraes,Claudia Trigo Pedroso
Oliveira,Danielle Bruna Leal
Lima,Hildener Nogueira
Vieira,Sandra Elisabete
Botosso,Viviane Fongaro
Zanotto,Paolo Marinho de Andrade
Stewien,Klaus Eberhard
dc.subject.por.fl_str_mv Human Respiratory Syncytial Virus
G Glycoprotein
G2 Region
Phylogenetic Analysis
topic Human Respiratory Syncytial Virus
G Glycoprotein
G2 Region
Phylogenetic Analysis
description The Human Respiratory Syncytial Virus (HRSV), isolated in 1955, is the main cause of hospitalization of babies and infants with respiratory illness. Several studies have been conducted worldwide aiming the development of a safe and effective vaccine against HRSV. The G2 region of glycoprotein G is used as genotyping default. In the present study, we performed a phylogenetic analysis of G protein and a comparative study between G2 region and ectodomain of attachment glycoprotein. Fifty-three nasal swab samples from children less than 5 years old and presenting symptoms of acute respiratory illness, assisted at the University Hospital (UH) of University of Sao Paulo (USP) in 2004, were submitted to sequencing by PCR and compared with GenBank sequences. We concluded that the G2 region is adequate for HRSV genotyping.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1517-83822007000300005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.38 n.3 2007
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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