Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli

Detalhes bibliográficos
Autor(a) principal: Li,Li
Data de Publicação: 2014
Outros Autores: Shi,Chaofeng, Yin,Zhongqiong, Jia,Renyong, Peng,Lianci, Kang,Shuai, Li,Zhengwen
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400035
Resumo: The antibacterial effect of α-terpineol from Cinnamomum longepaniculatum (Gamble) N. Chao leaf essential oils were studied with special reference to the mechanism of inhibiting the standard strain of Escherichia coli (CMCC (B) 44102) growth at ultrastructural level. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) and time-kill curves of α-terpineol were determined; Escherichia coli was treated with α-terpineol and observed under a transmission electron microscope. The MIC and MBC values of α-terpineol were all 0.78 µL/mL, and time-kill curves showed the concentration-dependent. Under the transmission electron microscopy (TEM), Escherichia coli exposed to MIC levels of α-terpineol exhibited decreased cell size and irregular cell shape, cell wall and cell membrane were ruptured, nucleus cytoplasm was reduced and nuclear area gathered aside. Results suggest that α-terpineol has excellent antibacterial activity and could induce morphological changes of Escherichia coli.
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spelling Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coliα-terpineolEscherichia coliantibacterial activityTEMThe antibacterial effect of α-terpineol from Cinnamomum longepaniculatum (Gamble) N. Chao leaf essential oils were studied with special reference to the mechanism of inhibiting the standard strain of Escherichia coli (CMCC (B) 44102) growth at ultrastructural level. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) and time-kill curves of α-terpineol were determined; Escherichia coli was treated with α-terpineol and observed under a transmission electron microscope. The MIC and MBC values of α-terpineol were all 0.78 µL/mL, and time-kill curves showed the concentration-dependent. Under the transmission electron microscopy (TEM), Escherichia coli exposed to MIC levels of α-terpineol exhibited decreased cell size and irregular cell shape, cell wall and cell membrane were ruptured, nucleus cytoplasm was reduced and nuclear area gathered aside. Results suggest that α-terpineol has excellent antibacterial activity and could induce morphological changes of Escherichia coli.Sociedade Brasileira de Microbiologia2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400035Brazilian Journal of Microbiology v.45 n.4 2014reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822014000400035info:eu-repo/semantics/openAccessLi,LiShi,ChaofengYin,ZhongqiongJia,RenyongPeng,LianciKang,ShuaiLi,Zhengweneng2015-02-13T00:00:00Zoai:scielo:S1517-83822014000400035Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2015-02-13T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
title Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
spellingShingle Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
Li,Li
α-terpineol
Escherichia coli
antibacterial activity
TEM
title_short Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
title_full Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
title_fullStr Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
title_full_unstemmed Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
title_sort Antibacterial activity of α-terpineol may induce morphostructural alterations in Escherichia coli
author Li,Li
author_facet Li,Li
Shi,Chaofeng
Yin,Zhongqiong
Jia,Renyong
Peng,Lianci
Kang,Shuai
Li,Zhengwen
author_role author
author2 Shi,Chaofeng
Yin,Zhongqiong
Jia,Renyong
Peng,Lianci
Kang,Shuai
Li,Zhengwen
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Li,Li
Shi,Chaofeng
Yin,Zhongqiong
Jia,Renyong
Peng,Lianci
Kang,Shuai
Li,Zhengwen
dc.subject.por.fl_str_mv α-terpineol
Escherichia coli
antibacterial activity
TEM
topic α-terpineol
Escherichia coli
antibacterial activity
TEM
description The antibacterial effect of α-terpineol from Cinnamomum longepaniculatum (Gamble) N. Chao leaf essential oils were studied with special reference to the mechanism of inhibiting the standard strain of Escherichia coli (CMCC (B) 44102) growth at ultrastructural level. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) and time-kill curves of α-terpineol were determined; Escherichia coli was treated with α-terpineol and observed under a transmission electron microscope. The MIC and MBC values of α-terpineol were all 0.78 µL/mL, and time-kill curves showed the concentration-dependent. Under the transmission electron microscopy (TEM), Escherichia coli exposed to MIC levels of α-terpineol exhibited decreased cell size and irregular cell shape, cell wall and cell membrane were ruptured, nucleus cytoplasm was reduced and nuclear area gathered aside. Results suggest that α-terpineol has excellent antibacterial activity and could induce morphological changes of Escherichia coli.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400035
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400035
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1517-83822014000400035
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.45 n.4 2014
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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