Low prevalence of high risk human papillomavirus in normal oral mucosa by hybrid capture 2

• Autor(a) principal: González-Losa,Maria del Refugio
• Data de Publicação: 2008
• Outros Autores: Manzano-Cabrera,Luis, Rueda-Gordillo,Florencio, Hernández-Solís,Sandra E., Puerto-Solís,Marylin
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Brazilian Journal of Microbiology
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000100008
• topic: Papillomavirus; hybrid capture 2; oral mucosa; squamous cell carcinoma; high risk

High risk human papillomavirus (HR-HPV) are recognized as a necessary factor to development cervical cancer. During the last decade many studies have found HR-HPV in oral squamous cell carcinoma (OSCC) and normal oral mucosa, however the association between HR-HPV and OSCC is still uncertain. The aim of the study was to determine DNA HR-HPV in normal oral cavity of healthy adults. A cross-sectional study was performed; samples from 77 patients with normal oral cavity were collected at the Dentistry school, Autonomous University of Yucatan, Merida, Yucatan, México. HR-HPV was detected by hybrid capture 2. One sample out of 77(1.2%) was positive for HR-PVH. It was from a man of 50 years old. HR-HPV is present in low rate among healthy oral mucosa. Hybrid capture 2 could be a good methodology for large epidemiology studies.