EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE

Detalhes bibliográficos
Autor(a) principal: Fernandes,Wendel Simões
Data de Publicação: 2021
Outros Autores: Vieira,Rodolfo de Paula, Ferreira,Ricardo César Alves, Ferreira,Sérgio César, Conceição,Viviane Gadret Bório, Morais,Flávia Villaça, Araújo,Aline Neves, Miranda,Priscila Ebram de, Destefano,Patrícia, Ribeiro,Wellington
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de medicina do esporte (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134
Resumo: ABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study .
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spelling EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICECreatineMuscle fatigueSildenafil citrateABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study .Sociedade Brasileira de Medicina do Exercício e do Esporte2021-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134Revista Brasileira de Medicina do Esporte v.27 n.2 2021reponame:Revista brasileira de medicina do esporte (Online)instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)instacron:SBMEE10.1590/1517-869220212702153173info:eu-repo/semantics/openAccessFernandes,Wendel SimõesVieira,Rodolfo de PaulaFerreira,Ricardo César AlvesFerreira,Sérgio CésarConceição,Viviane Gadret BórioMorais,Flávia VillaçaAraújo,Aline NevesMiranda,Priscila Ebram deDestefano,PatríciaRibeiro,Wellingtoneng2021-06-11T00:00:00Zoai:scielo:S1517-86922021000200134Revistahttp://www.scielo.br/rbmeONGhttps://old.scielo.br/oai/scielo-oai.php||revista@medicinadoesporte.org.br1806-99401517-8692opendoar:2021-06-11T00:00Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)false
dc.title.none.fl_str_mv EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
title EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
spellingShingle EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
Fernandes,Wendel Simões
Creatine
Muscle fatigue
Sildenafil citrate
title_short EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
title_full EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
title_fullStr EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
title_full_unstemmed EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
title_sort EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
author Fernandes,Wendel Simões
author_facet Fernandes,Wendel Simões
Vieira,Rodolfo de Paula
Ferreira,Ricardo César Alves
Ferreira,Sérgio César
Conceição,Viviane Gadret Bório
Morais,Flávia Villaça
Araújo,Aline Neves
Miranda,Priscila Ebram de
Destefano,Patrícia
Ribeiro,Wellington
author_role author
author2 Vieira,Rodolfo de Paula
Ferreira,Ricardo César Alves
Ferreira,Sérgio César
Conceição,Viviane Gadret Bório
Morais,Flávia Villaça
Araújo,Aline Neves
Miranda,Priscila Ebram de
Destefano,Patrícia
Ribeiro,Wellington
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fernandes,Wendel Simões
Vieira,Rodolfo de Paula
Ferreira,Ricardo César Alves
Ferreira,Sérgio César
Conceição,Viviane Gadret Bório
Morais,Flávia Villaça
Araújo,Aline Neves
Miranda,Priscila Ebram de
Destefano,Patrícia
Ribeiro,Wellington
dc.subject.por.fl_str_mv Creatine
Muscle fatigue
Sildenafil citrate
topic Creatine
Muscle fatigue
Sildenafil citrate
description ABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study .
publishDate 2021
dc.date.none.fl_str_mv 2021-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134
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dc.language.iso.fl_str_mv eng
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina do Exercício e do Esporte
publisher.none.fl_str_mv Sociedade Brasileira de Medicina do Exercício e do Esporte
dc.source.none.fl_str_mv Revista Brasileira de Medicina do Esporte v.27 n.2 2021
reponame:Revista brasileira de medicina do esporte (Online)
instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)
instacron:SBMEE
instname_str Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)
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reponame_str Revista brasileira de medicina do esporte (Online)
collection Revista brasileira de medicina do esporte (Online)
repository.name.fl_str_mv Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)
repository.mail.fl_str_mv ||revista@medicinadoesporte.org.br
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