EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista brasileira de medicina do esporte (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134 |
Resumo: | ABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study . |
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EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICECreatineMuscle fatigueSildenafil citrateABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study .Sociedade Brasileira de Medicina do Exercício e do Esporte2021-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134Revista Brasileira de Medicina do Esporte v.27 n.2 2021reponame:Revista brasileira de medicina do esporte (Online)instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)instacron:SBMEE10.1590/1517-869220212702153173info:eu-repo/semantics/openAccessFernandes,Wendel SimõesVieira,Rodolfo de PaulaFerreira,Ricardo César AlvesFerreira,Sérgio CésarConceição,Viviane Gadret BórioMorais,Flávia VillaçaAraújo,Aline NevesMiranda,Priscila Ebram deDestefano,PatríciaRibeiro,Wellingtoneng2021-06-11T00:00:00Zoai:scielo:S1517-86922021000200134Revistahttp://www.scielo.br/rbmeONGhttps://old.scielo.br/oai/scielo-oai.php||revista@medicinadoesporte.org.br1806-99401517-8692opendoar:2021-06-11T00:00Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)false |
dc.title.none.fl_str_mv |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
title |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
spellingShingle |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE Fernandes,Wendel Simões Creatine Muscle fatigue Sildenafil citrate |
title_short |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
title_full |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
title_fullStr |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
title_full_unstemmed |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
title_sort |
EFFECT OF CREATINE AND SILDENAFIL CITRATE ON THE PHYSICAL PERFORMANCE OF MICE |
author |
Fernandes,Wendel Simões |
author_facet |
Fernandes,Wendel Simões Vieira,Rodolfo de Paula Ferreira,Ricardo César Alves Ferreira,Sérgio César Conceição,Viviane Gadret Bório Morais,Flávia Villaça Araújo,Aline Neves Miranda,Priscila Ebram de Destefano,Patrícia Ribeiro,Wellington |
author_role |
author |
author2 |
Vieira,Rodolfo de Paula Ferreira,Ricardo César Alves Ferreira,Sérgio César Conceição,Viviane Gadret Bório Morais,Flávia Villaça Araújo,Aline Neves Miranda,Priscila Ebram de Destefano,Patrícia Ribeiro,Wellington |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fernandes,Wendel Simões Vieira,Rodolfo de Paula Ferreira,Ricardo César Alves Ferreira,Sérgio César Conceição,Viviane Gadret Bório Morais,Flávia Villaça Araújo,Aline Neves Miranda,Priscila Ebram de Destefano,Patrícia Ribeiro,Wellington |
dc.subject.por.fl_str_mv |
Creatine Muscle fatigue Sildenafil citrate |
topic |
Creatine Muscle fatigue Sildenafil citrate |
description |
ABSTRACT Introduction: The use of substances to enhance sports performance among professional and amateur athletes is increasing. Such substances may either be included in the group of dietary supplements or fall into pharmacological classes. Every substance used for this purpose is called an ergogenic agent. The number of ergogenic options available increases every day, favoring overuse and use without proper guidance. Among the dietary supplements, we highlight the use of creatine, a substance widespread in sports. Among the pharmacological groups, many drugs are used. Recently the use of sildenafil citrate by professional athletes from various predominantly aerobic sports modalities was reported in the media. Objective: To compare and demonstrate the responses caused by physical training associated with the use of creatine and sildenafil citrate in mice. Methods: A swim training protocol was applied and then an electrophysiograph was used in order to obtain parameters related to contraction intensity, the area under the curve and the percentage drop. Results: The responses obtained demonstrated the ergogenic action of creatine because it altered the parameters used for measurement. The use of sildenafil citrate did not yield satisfactory results to frame the drug as an ergogenic agent. Conclusion: Creatine has an ergogenic effect, reducing the percentage drop after 10 seconds, while sildenafil demonstrated no ergogenic potential and, interestingly, resulted in weaker responses when compared to the exercise groups. Evidence level II; Comparative prospective study . |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922021000200134 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1517-869220212702153173 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina do Exercício e do Esporte |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina do Exercício e do Esporte |
dc.source.none.fl_str_mv |
Revista Brasileira de Medicina do Esporte v.27 n.2 2021 reponame:Revista brasileira de medicina do esporte (Online) instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) instacron:SBMEE |
instname_str |
Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) |
instacron_str |
SBMEE |
institution |
SBMEE |
reponame_str |
Revista brasileira de medicina do esporte (Online) |
collection |
Revista brasileira de medicina do esporte (Online) |
repository.name.fl_str_mv |
Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) |
repository.mail.fl_str_mv |
||revista@medicinadoesporte.org.br |
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1752122237578641408 |