ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista brasileira de medicina do esporte (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922017000600469 |
Resumo: | ABSTRACT Introduction: By associating genetics and sport, it is possible to identify subjects with greater capacity to adapt to training, and lower chances of injury. Objective: The investigation evaluated the genotypic and allelic distribution of ACTN3 R577X and ACE I/D polymorphisms in Brazilian high-performance athletes in wrestling and percussion combat sports. Methods: The study included 37 male athletes ranked from first to third place in world scenarios, divided into two groups: wrestling (23 wrestlers, being 11 of Judo, 4 of Greco-Roman style, 8 of Brazilian Jiu Jitsu, with mean age of 27.3 ± 6.9 years) and percussion combat sports (14 athletes with a mean age of 25.7±4.4 years, being 6 of Karate, 3 of Muay Thai, 4 of Taekwondo, 1 Boxing). Genotyping of ACTN3 and ACE I/D polymorphisms was performed by polymerase chain reaction (PCR) from the genomic DNA. Genotypic and allelic distributions were compared with control populations and athletes by Chi-square test and Fisher’s exact test; all analyzes considered p ≤ 0.05. Results: The genotypic distributions and allelic frequencies of ACTN3 RR=46%, RX=38% and XX=16%; R=65% and X=35%, and ACE I/D DD=47.7%, ID=34.3% and II=20%; D=62.9% and I=37.1% did not differ from the control population; however, when compared with wrestling athletes a significant difference was observed. Conclusion: These results suggest an association of ACTN3 R577X and ACE I/D genes with Brazilian high-performance wrestling athletes. |
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Revista brasileira de medicina do esporte (Online) |
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ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERSathletesactinin/geneticspeptidyl-dipeptidase Aethnic groups/genetics.ABSTRACT Introduction: By associating genetics and sport, it is possible to identify subjects with greater capacity to adapt to training, and lower chances of injury. Objective: The investigation evaluated the genotypic and allelic distribution of ACTN3 R577X and ACE I/D polymorphisms in Brazilian high-performance athletes in wrestling and percussion combat sports. Methods: The study included 37 male athletes ranked from first to third place in world scenarios, divided into two groups: wrestling (23 wrestlers, being 11 of Judo, 4 of Greco-Roman style, 8 of Brazilian Jiu Jitsu, with mean age of 27.3 ± 6.9 years) and percussion combat sports (14 athletes with a mean age of 25.7±4.4 years, being 6 of Karate, 3 of Muay Thai, 4 of Taekwondo, 1 Boxing). Genotyping of ACTN3 and ACE I/D polymorphisms was performed by polymerase chain reaction (PCR) from the genomic DNA. Genotypic and allelic distributions were compared with control populations and athletes by Chi-square test and Fisher’s exact test; all analyzes considered p ≤ 0.05. Results: The genotypic distributions and allelic frequencies of ACTN3 RR=46%, RX=38% and XX=16%; R=65% and X=35%, and ACE I/D DD=47.7%, ID=34.3% and II=20%; D=62.9% and I=37.1% did not differ from the control population; however, when compared with wrestling athletes a significant difference was observed. Conclusion: These results suggest an association of ACTN3 R577X and ACE I/D genes with Brazilian high-performance wrestling athletes.Sociedade Brasileira de Medicina do Exercício e do Esporte2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922017000600469Revista Brasileira de Medicina do Esporte v.23 n.6 2017reponame:Revista brasileira de medicina do esporte (Online)instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)instacron:SBMEE10.1590/1517-869220172306171864info:eu-repo/semantics/openAccessRibas,Marcelo RomanovitchOliveira Netto,Zair CandidoSalgueirosa,FabianoFernandes,PriscilaMatos,Oslei deBassan,Julio Cesareng2017-12-14T00:00:00Zoai:scielo:S1517-86922017000600469Revistahttp://www.scielo.br/rbmeONGhttps://old.scielo.br/oai/scielo-oai.php||revista@medicinadoesporte.org.br1806-99401517-8692opendoar:2017-12-14T00:00Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE)false |
dc.title.none.fl_str_mv |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
title |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
spellingShingle |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS Ribas,Marcelo Romanovitch athletes actinin/genetics peptidyl-dipeptidase A ethnic groups/genetics. |
title_short |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
title_full |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
title_fullStr |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
title_full_unstemmed |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
title_sort |
ASSOCIATION OF ACTN3 R577X AND ACE I/D POLYMORPHISMS IN BRAZILIANS WRESTLERS |
author |
Ribas,Marcelo Romanovitch |
author_facet |
Ribas,Marcelo Romanovitch Oliveira Netto,Zair Candido Salgueirosa,Fabiano Fernandes,Priscila Matos,Oslei de Bassan,Julio Cesar |
author_role |
author |
author2 |
Oliveira Netto,Zair Candido Salgueirosa,Fabiano Fernandes,Priscila Matos,Oslei de Bassan,Julio Cesar |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Ribas,Marcelo Romanovitch Oliveira Netto,Zair Candido Salgueirosa,Fabiano Fernandes,Priscila Matos,Oslei de Bassan,Julio Cesar |
dc.subject.por.fl_str_mv |
athletes actinin/genetics peptidyl-dipeptidase A ethnic groups/genetics. |
topic |
athletes actinin/genetics peptidyl-dipeptidase A ethnic groups/genetics. |
description |
ABSTRACT Introduction: By associating genetics and sport, it is possible to identify subjects with greater capacity to adapt to training, and lower chances of injury. Objective: The investigation evaluated the genotypic and allelic distribution of ACTN3 R577X and ACE I/D polymorphisms in Brazilian high-performance athletes in wrestling and percussion combat sports. Methods: The study included 37 male athletes ranked from first to third place in world scenarios, divided into two groups: wrestling (23 wrestlers, being 11 of Judo, 4 of Greco-Roman style, 8 of Brazilian Jiu Jitsu, with mean age of 27.3 ± 6.9 years) and percussion combat sports (14 athletes with a mean age of 25.7±4.4 years, being 6 of Karate, 3 of Muay Thai, 4 of Taekwondo, 1 Boxing). Genotyping of ACTN3 and ACE I/D polymorphisms was performed by polymerase chain reaction (PCR) from the genomic DNA. Genotypic and allelic distributions were compared with control populations and athletes by Chi-square test and Fisher’s exact test; all analyzes considered p ≤ 0.05. Results: The genotypic distributions and allelic frequencies of ACTN3 RR=46%, RX=38% and XX=16%; R=65% and X=35%, and ACE I/D DD=47.7%, ID=34.3% and II=20%; D=62.9% and I=37.1% did not differ from the control population; however, when compared with wrestling athletes a significant difference was observed. Conclusion: These results suggest an association of ACTN3 R577X and ACE I/D genes with Brazilian high-performance wrestling athletes. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922017000600469 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-86922017000600469 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1517-869220172306171864 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina do Exercício e do Esporte |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina do Exercício e do Esporte |
dc.source.none.fl_str_mv |
Revista Brasileira de Medicina do Esporte v.23 n.6 2017 reponame:Revista brasileira de medicina do esporte (Online) instname:Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) instacron:SBMEE |
instname_str |
Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) |
instacron_str |
SBMEE |
institution |
SBMEE |
reponame_str |
Revista brasileira de medicina do esporte (Online) |
collection |
Revista brasileira de medicina do esporte (Online) |
repository.name.fl_str_mv |
Revista brasileira de medicina do esporte (Online) - Sociedade Brasileira de Medicina do Exercício e do Esporte (SBMEE) |
repository.mail.fl_str_mv |
||revista@medicinadoesporte.org.br |
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1752122236194521088 |