Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin

Detalhes bibliográficos
Autor(a) principal: Brasil, Fábio
Data de Publicação: 2010
Outros Autores: Brasil, Andreia Mara Brolezzi
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Medicina de Família e Comunidade (Online)
Texto Completo: https://www.rbmfc.org.br/rbmfc/article/view/200
Resumo: This transverse study was undertaken to assess serum lipoprotein cholesterol, glycated hemoglobin (HbA1c) and triglyceride levels of 105 patients with type 2 diabetes mellitus in insulin use belonging to a health care area of the Family Health Program (FHP). It had as objective to identify possible variations in those parameters when metformin is associated to the treatment. Thirty-three of those patients were excluded by presenting inclinations. Of the remaining, 44 subjects were on combination therapy of metformin and insulin – these indicated serum levels of HbA1c and triglycerides significantly lower than the control group in treatment with insulin alone (n=28); statistical differences were not observed regarding high-density lipoprotein and total cholesterol levels. The research appeared that, due to free readiness of metformin for the population, combined therapy should be used as first choice in public health.
id SBMFC-1_c57d44f388ecebb5f21dc2a06463835f
oai_identifier_str oai:ojs.rbmfc.org.br:article/200
network_acronym_str SBMFC-1
network_name_str Revista Brasileira de Medicina de Família e Comunidade (Online)
repository_id_str
spelling Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulinControle glicêmico e lipídico de pacientes com diabete tipo 2 em tratamento combinado de metformina e insulinaMetforminInsulinLipidsDiabetes MellitusMetforminaInsulinaLipídiosDiabetes MellitusThis transverse study was undertaken to assess serum lipoprotein cholesterol, glycated hemoglobin (HbA1c) and triglyceride levels of 105 patients with type 2 diabetes mellitus in insulin use belonging to a health care area of the Family Health Program (FHP). It had as objective to identify possible variations in those parameters when metformin is associated to the treatment. Thirty-three of those patients were excluded by presenting inclinations. Of the remaining, 44 subjects were on combination therapy of metformin and insulin – these indicated serum levels of HbA1c and triglycerides significantly lower than the control group in treatment with insulin alone (n=28); statistical differences were not observed regarding high-density lipoprotein and total cholesterol levels. The research appeared that, due to free readiness of metformin for the population, combined therapy should be used as first choice in public health.Este é um estudo transversal em que foram avaliados os dados laboratoriais de perfil lipídico e hemoglobina glicada (HbA1c) dos 105 pacientes portadores de diabetes mellitus tipo 2 em uso de insulina na área adstrita da Unidade de Saúde São Paulo do Programa de Saúde da Família. Teve como objetivo identificar possíveis variações nesses parâmetros quando associada metformina ao tratamento. Desses pacientes, 33 foram excluídos por apresentarem vieses. Dos restantes, 44 estavam em tratamento combinado de metformina e insulina – estes apresentaram níveis de HbA1c e triglicerídeos significativamente inferiores ao grupo controle em tratamento isolado com insulina (n=28); não se observaram diferenças de significado estatístico com relação ao colesterol total e HDL. O estudo sugeriu que, pela disponibilidade gratuita da metformina para a população, tal associação deveria ser considerada como primeira escolha em saúde pública.Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)2010-03-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos Originais; Original Articlesapplication/pdfhttps://www.rbmfc.org.br/rbmfc/article/view/20010.5712/rbmfc5(17)200Revista Brasileira de Medicina de Família e Comunidade; Vol. 5 No. 17 (2010); 33-37Revista Brasileira de Medicina de Família e Comunidade; Vol. 5 Núm. 17 (2010); 33-37Revista Brasileira de Medicina de Família e Comunidade; v. 5 n. 17 (2010); 33-372179-79941809-5909reponame:Revista Brasileira de Medicina de Família e Comunidade (Online)instname:Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)instacron:SBMFCporhttps://www.rbmfc.org.br/rbmfc/article/view/200/152Copyright (c) 2010 Fábio Brasil, Andreia Mara Brolezzi Brasilinfo:eu-repo/semantics/openAccessBrasil, FábioBrasil, Andreia Mara Brolezzi2020-05-22T06:21:57Zoai:ojs.rbmfc.org.br:article/200Revistahttp://www.rbmfc.org.br/index.php/rbmfchttps://www.rbmfc.org.br/rbmfc/oai||david@sbmfc.org.br2179-79941809-5909opendoar:2020-05-22T06:21:57Revista Brasileira de Medicina de Família e Comunidade (Online) - Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)false
dc.title.none.fl_str_mv Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
Controle glicêmico e lipídico de pacientes com diabete tipo 2 em tratamento combinado de metformina e insulina
title Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
spellingShingle Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
Brasil, Fábio
Metformin
Insulin
Lipids
Diabetes Mellitus
Metformina
Insulina
Lipídios
Diabetes Mellitus
title_short Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
title_full Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
title_fullStr Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
title_full_unstemmed Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
title_sort Glycemic and lipid control of patients with type 2 diabetes in combined treatment of metformin and insulin
author Brasil, Fábio
author_facet Brasil, Fábio
Brasil, Andreia Mara Brolezzi
author_role author
author2 Brasil, Andreia Mara Brolezzi
author2_role author
dc.contributor.author.fl_str_mv Brasil, Fábio
Brasil, Andreia Mara Brolezzi
dc.subject.por.fl_str_mv Metformin
Insulin
Lipids
Diabetes Mellitus
Metformina
Insulina
Lipídios
Diabetes Mellitus
topic Metformin
Insulin
Lipids
Diabetes Mellitus
Metformina
Insulina
Lipídios
Diabetes Mellitus
description This transverse study was undertaken to assess serum lipoprotein cholesterol, glycated hemoglobin (HbA1c) and triglyceride levels of 105 patients with type 2 diabetes mellitus in insulin use belonging to a health care area of the Family Health Program (FHP). It had as objective to identify possible variations in those parameters when metformin is associated to the treatment. Thirty-three of those patients were excluded by presenting inclinations. Of the remaining, 44 subjects were on combination therapy of metformin and insulin – these indicated serum levels of HbA1c and triglycerides significantly lower than the control group in treatment with insulin alone (n=28); statistical differences were not observed regarding high-density lipoprotein and total cholesterol levels. The research appeared that, due to free readiness of metformin for the population, combined therapy should be used as first choice in public health.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos Originais; Original Articles
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.rbmfc.org.br/rbmfc/article/view/200
10.5712/rbmfc5(17)200
url https://www.rbmfc.org.br/rbmfc/article/view/200
identifier_str_mv 10.5712/rbmfc5(17)200
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.rbmfc.org.br/rbmfc/article/view/200/152
dc.rights.driver.fl_str_mv Copyright (c) 2010 Fábio Brasil, Andreia Mara Brolezzi Brasil
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2010 Fábio Brasil, Andreia Mara Brolezzi Brasil
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
publisher.none.fl_str_mv Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
dc.source.none.fl_str_mv Revista Brasileira de Medicina de Família e Comunidade; Vol. 5 No. 17 (2010); 33-37
Revista Brasileira de Medicina de Família e Comunidade; Vol. 5 Núm. 17 (2010); 33-37
Revista Brasileira de Medicina de Família e Comunidade; v. 5 n. 17 (2010); 33-37
2179-7994
1809-5909
reponame:Revista Brasileira de Medicina de Família e Comunidade (Online)
instname:Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
instacron:SBMFC
instname_str Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
instacron_str SBMFC
institution SBMFC
reponame_str Revista Brasileira de Medicina de Família e Comunidade (Online)
collection Revista Brasileira de Medicina de Família e Comunidade (Online)
repository.name.fl_str_mv Revista Brasileira de Medicina de Família e Comunidade (Online) - Sociedade Brasileira de Medicina de Família e Comunidade (SBMFC)
repository.mail.fl_str_mv ||david@sbmfc.org.br
_version_ 1752122105190678528

Registros relacionados