Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats

Detalhes bibliográficos
Autor(a) principal: Santos,Carolina Cincurá Silva
Data de Publicação: 2007
Outros Autores: Onofre-Nunes,Záira, Andrade,Zilton Araujo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822007000500001
Resumo: It is known that hepatic fibrosis may regress following partial hepatectomy, since the hepatic parenchyma regenerates very rapidly, but not the excess of fibrous tissue. The present study evaluated this hypothesis by observing the behavior of systematized septal fibrosis induced by either 30 or 90-day-old Capillaria hepatica infection, in rats subjected to partial hepatectomy. The results revealed that the morphology of the fibrosis was unaffected, but its relative quantity within the microscope field appeared significantly decreased, as a consequence of the increased liver tissue mass following regeneration.
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spelling Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in ratsHepatectomyFibrosisCapillaria hepaticaIt is known that hepatic fibrosis may regress following partial hepatectomy, since the hepatic parenchyma regenerates very rapidly, but not the excess of fibrous tissue. The present study evaluated this hypothesis by observing the behavior of systematized septal fibrosis induced by either 30 or 90-day-old Capillaria hepatica infection, in rats subjected to partial hepatectomy. The results revealed that the morphology of the fibrosis was unaffected, but its relative quantity within the microscope field appeared significantly decreased, as a consequence of the increased liver tissue mass following regeneration.Sociedade Brasileira de Medicina Tropical - SBMT2007-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822007000500001Revista da Sociedade Brasileira de Medicina Tropical v.40 n.5 2007reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822007000500001info:eu-repo/semantics/openAccessSantos,Carolina Cincurá SilvaOnofre-Nunes,ZáiraAndrade,Zilton Araujoeng2007-10-31T00:00:00Zoai:scielo:S0037-86822007000500001Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2007-10-31T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
title Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
spellingShingle Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
Santos,Carolina Cincurá Silva
Hepatectomy
Fibrosis
Capillaria hepatica
title_short Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
title_full Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
title_fullStr Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
title_full_unstemmed Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
title_sort Role of partial hepatectomy on Capillaria hepatica-induced hepatic fibrosis in rats
author Santos,Carolina Cincurá Silva
author_facet Santos,Carolina Cincurá Silva
Onofre-Nunes,Záira
Andrade,Zilton Araujo
author_role author
author2 Onofre-Nunes,Záira
Andrade,Zilton Araujo
author2_role author
author
dc.contributor.author.fl_str_mv Santos,Carolina Cincurá Silva
Onofre-Nunes,Záira
Andrade,Zilton Araujo
dc.subject.por.fl_str_mv Hepatectomy
Fibrosis
Capillaria hepatica
topic Hepatectomy
Fibrosis
Capillaria hepatica
description It is known that hepatic fibrosis may regress following partial hepatectomy, since the hepatic parenchyma regenerates very rapidly, but not the excess of fibrous tissue. The present study evaluated this hypothesis by observing the behavior of systematized septal fibrosis induced by either 30 or 90-day-old Capillaria hepatica infection, in rats subjected to partial hepatectomy. The results revealed that the morphology of the fibrosis was unaffected, but its relative quantity within the microscope field appeared significantly decreased, as a consequence of the increased liver tissue mass following regeneration.
publishDate 2007
dc.date.none.fl_str_mv 2007-10-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822007000500001
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822007000500001
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.40 n.5 2007
reponame:Revista da Sociedade Brasileira de Medicina Tropical
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reponame_str Revista da Sociedade Brasileira de Medicina Tropical
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repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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