Severe coinfection of melioidosis and dengue fever in northeastern Brazil: first case report

• Autor(a) principal: Macedo,Rafael Nogueira
• Data de Publicação: 2012
• Outros Autores: Rocha,Felipe Araujo, Rolim,Dionne Bezerra, Vilar,Dina Cortez Lima Feitosa, Araújo,Fernanda Montenegro de Carvalho, Vieira,Nélia Nogueira, Teixeira,Juliana Rodrigues, Carvalho,Maíza Colares, Oliveira,Francisco George Magalhães, Cavalcanti,Luciano Pamplona de Góes
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000100028
• topic: Melioidosis; Dengue fever; Coinfection

This report focuses on a fatality involving severe dengue fever and melioidosis in a 28-year-old truck driver residing in Pacoti in northeastern Brazil. He exhibited long-term respiratory symptoms (48 days) and went through a wide-ranging clinical investigation at three hospitals, after initial clinical diagnoses of pneumonia, visceral leishmaniasis, tuberculosis, and fungal sepsis. After death, Burkholderia pseudomallei was isolated in a culture of ascitic fluid. Dengue virus type 1 was detected by polymerase chain reaction in cerebrospinal fluid (CSF); this infection was the cause of death. This description reinforces the need to consider melioidosis among the reported differential diagnoses of community-acquired infections where both melioidosis and dengue fever are endemic.