Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report

• Autor(a) principal: Andrade,Solange Dourado de
• Data de Publicação: 2015
• Outros Autores: Andrade,Maria Graciede Filha Santarém, Santos,Pablo José, Galvão,Maria de Lourdes, Barros,Mariana Martins de, Ramasawmy,Rajendranath, Safe,Izabella Picinin, Monteiro,Wuelton Marcelo, Sabidó,Meritxell, Alecrim,Maria das Graças Costa
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000400498
• topic: Acute disseminated encephalomyelitis; Inactivated influenza vaccination; Brazilian Amazon.

AbstractHere, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.