Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Sociedade Brasileira de Medicina Tropical |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010 |
Resumo: | The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones. |
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Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein dietsSchistosoma mansoniUndernutritionMiceIntestinal mucosaHistomorphometryThe effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones.Sociedade Brasileira de Medicina Tropical - SBMT2002-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010Revista da Sociedade Brasileira de Medicina Tropical v.35 n.6 2002reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822002000600010info:eu-repo/semantics/openAccessCouto,Janira Lúcia AssumpçãoFerreira,Haroldo da SilvaRocha,Dinalva Bezerra daDuarte,Maria Eugênia LeiteAssunção,Monica LopesCoutinho,Eridan de Medeiroseng2003-02-26T00:00:00Zoai:scielo:S0037-86822002000600010Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2003-02-26T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
spellingShingle |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets Couto,Janira Lúcia Assumpção Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry |
title_short |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_full |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_fullStr |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_full_unstemmed |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
title_sort |
Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets |
author |
Couto,Janira Lúcia Assumpção |
author_facet |
Couto,Janira Lúcia Assumpção Ferreira,Haroldo da Silva Rocha,Dinalva Bezerra da Duarte,Maria Eugênia Leite Assunção,Monica Lopes Coutinho,Eridan de Medeiros |
author_role |
author |
author2 |
Ferreira,Haroldo da Silva Rocha,Dinalva Bezerra da Duarte,Maria Eugênia Leite Assunção,Monica Lopes Coutinho,Eridan de Medeiros |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Couto,Janira Lúcia Assumpção Ferreira,Haroldo da Silva Rocha,Dinalva Bezerra da Duarte,Maria Eugênia Leite Assunção,Monica Lopes Coutinho,Eridan de Medeiros |
dc.subject.por.fl_str_mv |
Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry |
topic |
Schistosoma mansoni Undernutrition Mice Intestinal mucosa Histomorphometry |
description |
The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000600010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86822002000600010 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.35 n.6 2002 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
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1752122151941439488 |