Pyoderma gangrenosum and ulcerative colitis in the tropics

Detalhes bibliográficos
Autor(a) principal: Alese,Olatunji B.
Data de Publicação: 2008
Outros Autores: Irabor,David O.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822008000600020
Resumo: Pyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There have been some reports of the occurrence of pyoderma gangrenosum in Africa, and in Nigeria, but only one specifically reported pyoderma gangrenosum in association with ulcerative colitis. We report on a 45-year-old man who presented with pyoderma gangrenosum associated with ulcerative colitis; the second report in Nigeria. The skin lesions were managed with daily honey wound dressings. Oral dapsone and prednisolone were started. The frequency of the bloody diarrhea decreased, and was completely resolved by the second week after admission. The ulcers also showed accelerated healing. The goal of therapy is directed towards the associated systemic disorder, if present.
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spelling Pyoderma gangrenosum and ulcerative colitis in the tropicsPyoderma gangrenosumRectal bleedingBloody diarrheaColitisPyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There have been some reports of the occurrence of pyoderma gangrenosum in Africa, and in Nigeria, but only one specifically reported pyoderma gangrenosum in association with ulcerative colitis. We report on a 45-year-old man who presented with pyoderma gangrenosum associated with ulcerative colitis; the second report in Nigeria. The skin lesions were managed with daily honey wound dressings. Oral dapsone and prednisolone were started. The frequency of the bloody diarrhea decreased, and was completely resolved by the second week after admission. The ulcers also showed accelerated healing. The goal of therapy is directed towards the associated systemic disorder, if present.Sociedade Brasileira de Medicina Tropical - SBMT2008-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822008000600020Revista da Sociedade Brasileira de Medicina Tropical v.41 n.6 2008reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822008000600020info:eu-repo/semantics/openAccessAlese,Olatunji B.Irabor,David O.eng2009-01-05T00:00:00Zoai:scielo:S0037-86822008000600020Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2009-01-05T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Pyoderma gangrenosum and ulcerative colitis in the tropics
title Pyoderma gangrenosum and ulcerative colitis in the tropics
spellingShingle Pyoderma gangrenosum and ulcerative colitis in the tropics
Alese,Olatunji B.
Pyoderma gangrenosum
Rectal bleeding
Bloody diarrhea
Colitis
title_short Pyoderma gangrenosum and ulcerative colitis in the tropics
title_full Pyoderma gangrenosum and ulcerative colitis in the tropics
title_fullStr Pyoderma gangrenosum and ulcerative colitis in the tropics
title_full_unstemmed Pyoderma gangrenosum and ulcerative colitis in the tropics
title_sort Pyoderma gangrenosum and ulcerative colitis in the tropics
author Alese,Olatunji B.
author_facet Alese,Olatunji B.
Irabor,David O.
author_role author
author2 Irabor,David O.
author2_role author
dc.contributor.author.fl_str_mv Alese,Olatunji B.
Irabor,David O.
dc.subject.por.fl_str_mv Pyoderma gangrenosum
Rectal bleeding
Bloody diarrhea
Colitis
topic Pyoderma gangrenosum
Rectal bleeding
Bloody diarrhea
Colitis
description Pyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There have been some reports of the occurrence of pyoderma gangrenosum in Africa, and in Nigeria, but only one specifically reported pyoderma gangrenosum in association with ulcerative colitis. We report on a 45-year-old man who presented with pyoderma gangrenosum associated with ulcerative colitis; the second report in Nigeria. The skin lesions were managed with daily honey wound dressings. Oral dapsone and prednisolone were started. The frequency of the bloody diarrhea decreased, and was completely resolved by the second week after admission. The ulcers also showed accelerated healing. The goal of therapy is directed towards the associated systemic disorder, if present.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822008000600020
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.41 n.6 2008
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
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reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
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