Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Sociedade Brasileira de Medicina Tropical |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005 |
Resumo: | Lagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE. |
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Revista da Sociedade Brasileira de Medicina Tropical |
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Experimental lagochilascariosis in X-chromosome-linked immunodeficient miceB1 cellsBALB.xid miceLagochilascaris minorImmunoglobulinLagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE.Sociedade Brasileira de Medicina Tropical - SBMT2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005Revista da Sociedade Brasileira de Medicina Tropical v.42 n.4 2009reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822009000400005info:eu-repo/semantics/openAccessFreitas,Jaqueline Aparecida Gleice dePrudente,Mariana Félix de SouzaCarvalhaes,Mara Silviaeng2009-09-23T00:00:00Zoai:scielo:S0037-86822009000400005Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2009-09-23T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
title |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
spellingShingle |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice Freitas,Jaqueline Aparecida Gleice de B1 cells BALB.xid mice Lagochilascaris minor Immunoglobulin |
title_short |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
title_full |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
title_fullStr |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
title_full_unstemmed |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
title_sort |
Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice |
author |
Freitas,Jaqueline Aparecida Gleice de |
author_facet |
Freitas,Jaqueline Aparecida Gleice de Prudente,Mariana Félix de Souza Carvalhaes,Mara Silvia |
author_role |
author |
author2 |
Prudente,Mariana Félix de Souza Carvalhaes,Mara Silvia |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Freitas,Jaqueline Aparecida Gleice de Prudente,Mariana Félix de Souza Carvalhaes,Mara Silvia |
dc.subject.por.fl_str_mv |
B1 cells BALB.xid mice Lagochilascaris minor Immunoglobulin |
topic |
B1 cells BALB.xid mice Lagochilascaris minor Immunoglobulin |
description |
Lagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86822009000400005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.42 n.4 2009 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
_version_ |
1752122155252842496 |