Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice

Detalhes bibliográficos
Autor(a) principal: Freitas,Jaqueline Aparecida Gleice de
Data de Publicação: 2009
Outros Autores: Prudente,Mariana Félix de Souza, Carvalhaes,Mara Silvia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005
Resumo: Lagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE.
id SBMT-1_9fc7a8a5df210682136bbeae7c244c93
oai_identifier_str oai:scielo:S0037-86822009000400005
network_acronym_str SBMT-1
network_name_str Revista da Sociedade Brasileira de Medicina Tropical
repository_id_str
spelling Experimental lagochilascariosis in X-chromosome-linked immunodeficient miceB1 cellsBALB.xid miceLagochilascaris minorImmunoglobulinLagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE.Sociedade Brasileira de Medicina Tropical - SBMT2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005Revista da Sociedade Brasileira de Medicina Tropical v.42 n.4 2009reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822009000400005info:eu-repo/semantics/openAccessFreitas,Jaqueline Aparecida Gleice dePrudente,Mariana Félix de SouzaCarvalhaes,Mara Silviaeng2009-09-23T00:00:00Zoai:scielo:S0037-86822009000400005Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2009-09-23T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
title Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
spellingShingle Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
Freitas,Jaqueline Aparecida Gleice de
B1 cells
BALB.xid mice
Lagochilascaris minor
Immunoglobulin
title_short Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
title_full Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
title_fullStr Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
title_full_unstemmed Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
title_sort Experimental lagochilascariosis in X-chromosome-linked immunodeficient mice
author Freitas,Jaqueline Aparecida Gleice de
author_facet Freitas,Jaqueline Aparecida Gleice de
Prudente,Mariana Félix de Souza
Carvalhaes,Mara Silvia
author_role author
author2 Prudente,Mariana Félix de Souza
Carvalhaes,Mara Silvia
author2_role author
author
dc.contributor.author.fl_str_mv Freitas,Jaqueline Aparecida Gleice de
Prudente,Mariana Félix de Souza
Carvalhaes,Mara Silvia
dc.subject.por.fl_str_mv B1 cells
BALB.xid mice
Lagochilascaris minor
Immunoglobulin
topic B1 cells
BALB.xid mice
Lagochilascaris minor
Immunoglobulin
description Lagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE.
publishDate 2009
dc.date.none.fl_str_mv 2009-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822009000400005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822009000400005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.42 n.4 2009
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
_version_ 1752122155252842496