Low eligibility for hepatitis B treatment in the Brazilian public health system

Detalhes bibliográficos
Autor(a) principal: Scarponi,Cristiane Faria Oliveira
Data de Publicação: 2022
Outros Autores: Pedrosa,Marco Antônio Ferreira, Mol,Marcos Paulo Gomes, Hardman,Michael John Mascarenhas, Greco,Dirceu Bartolomeu
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307
Resumo: ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere.
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spelling Low eligibility for hepatitis B treatment in the Brazilian public health systemHepatitis BTreatment eligibilityGuideline adherenceAntiviral therapyPublic healthBrazilABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere.Sociedade Brasileira de Medicina Tropical - SBMT2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307Revista da Sociedade Brasileira de Medicina Tropical v.55 2022reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-0297-2021info:eu-repo/semantics/openAccessScarponi,Cristiane Faria OliveiraPedrosa,Marco Antônio FerreiraMol,Marcos Paulo GomesHardman,Michael John MascarenhasGreco,Dirceu Bartolomeueng2022-04-06T00:00:00Zoai:scielo:S0037-86822022000100307Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2022-04-06T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Low eligibility for hepatitis B treatment in the Brazilian public health system
title Low eligibility for hepatitis B treatment in the Brazilian public health system
spellingShingle Low eligibility for hepatitis B treatment in the Brazilian public health system
Scarponi,Cristiane Faria Oliveira
Hepatitis B
Treatment eligibility
Guideline adherence
Antiviral therapy
Public health
Brazil
title_short Low eligibility for hepatitis B treatment in the Brazilian public health system
title_full Low eligibility for hepatitis B treatment in the Brazilian public health system
title_fullStr Low eligibility for hepatitis B treatment in the Brazilian public health system
title_full_unstemmed Low eligibility for hepatitis B treatment in the Brazilian public health system
title_sort Low eligibility for hepatitis B treatment in the Brazilian public health system
author Scarponi,Cristiane Faria Oliveira
author_facet Scarponi,Cristiane Faria Oliveira
Pedrosa,Marco Antônio Ferreira
Mol,Marcos Paulo Gomes
Hardman,Michael John Mascarenhas
Greco,Dirceu Bartolomeu
author_role author
author2 Pedrosa,Marco Antônio Ferreira
Mol,Marcos Paulo Gomes
Hardman,Michael John Mascarenhas
Greco,Dirceu Bartolomeu
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Scarponi,Cristiane Faria Oliveira
Pedrosa,Marco Antônio Ferreira
Mol,Marcos Paulo Gomes
Hardman,Michael John Mascarenhas
Greco,Dirceu Bartolomeu
dc.subject.por.fl_str_mv Hepatitis B
Treatment eligibility
Guideline adherence
Antiviral therapy
Public health
Brazil
topic Hepatitis B
Treatment eligibility
Guideline adherence
Antiviral therapy
Public health
Brazil
description ABSTRACT Background: Chronic hepatitis B (CHB) affects 257 million people worldwide. However, the proportion of patients eligible for treatment in the public health system has not been established. This study describes the clinical and laboratory profiles of untreated CHB patients and estimates the eligibility rate for antiviral therapy in accordance with the Brazilian Clinical Protocol and Therapeutic Guidelines. Methods: Records of 670 CHB patients were collected from May 2012 to September 2013 in Minas Gerais. Data from each patient were analyzed by hepatitis B virus (HBV) management. Results: 461 CHB patients were treatment-naive. Of these, 23 were HBeAg-positive, 352 were HBeAg-negative, and 14 were clinically diagnosed with cirrhosis. Periodic monitoring was performed in only three patients. However, 9.3% of untreated patients met the eligibility criteria for HBV treatment. Conclusions: Few CHB patients were active carriers and eligible candidates for antiviral therapy. This study revealed inadequate pre-treatment conduct in the Brazilian public health system, emphasizing the need for regular laboratory follow-up for patients initially not eligible for treatment. Such information may indirectly subsidize the planning and improvement of actions and services related to optimal HBV management in the public sphere.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822022000100307
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0037-8682-0297-2021
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.55 2022
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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