Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges

Detalhes bibliográficos
Autor(a) principal: Costa,Henrique Silveira
Data de Publicação: 2020
Outros Autores: Lima,Márcia Maria Oliveira, Figueiredo,Pedro Henrique Scheidt, Lima,Vanessa Pereira, Ávila,Matheus Ribeiro, Menezes,Kenia Kiefer Parreiras de, Mendonça,Vanessa Amaral, Lacerda,Ana Cristina Rodrigues, Nunes,Maria Carmo Pereira, Mediano,Mauro Felippe Felix, Rocha,Manoel Otávio da Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100204
Resumo: Abstract Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases.
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spelling Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challengesChagas diseaseChagas cardiomyopathyExercise testExercise toleranceEvaluationPrognosisAbstract Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases.Sociedade Brasileira de Medicina Tropical - SBMT2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100204Revista da Sociedade Brasileira de Medicina Tropical v.53 2020reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-0100-2020info:eu-repo/semantics/openAccessCosta,Henrique SilveiraLima,Márcia Maria OliveiraFigueiredo,Pedro Henrique ScheidtLima,Vanessa PereiraÁvila,Matheus RibeiroMenezes,Kenia Kiefer Parreiras deMendonça,Vanessa AmaralLacerda,Ana Cristina RodriguesNunes,Maria Carmo PereiraMediano,Mauro Felippe FelixRocha,Manoel Otávio da Costaeng2020-06-30T00:00:00Zoai:scielo:S0037-86822020000100204Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2020-06-30T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
spellingShingle Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
Costa,Henrique Silveira
Chagas disease
Chagas cardiomyopathy
Exercise test
Exercise tolerance
Evaluation
Prognosis
title_short Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_full Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_fullStr Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_full_unstemmed Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_sort Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
author Costa,Henrique Silveira
author_facet Costa,Henrique Silveira
Lima,Márcia Maria Oliveira
Figueiredo,Pedro Henrique Scheidt
Lima,Vanessa Pereira
Ávila,Matheus Ribeiro
Menezes,Kenia Kiefer Parreiras de
Mendonça,Vanessa Amaral
Lacerda,Ana Cristina Rodrigues
Nunes,Maria Carmo Pereira
Mediano,Mauro Felippe Felix
Rocha,Manoel Otávio da Costa
author_role author
author2 Lima,Márcia Maria Oliveira
Figueiredo,Pedro Henrique Scheidt
Lima,Vanessa Pereira
Ávila,Matheus Ribeiro
Menezes,Kenia Kiefer Parreiras de
Mendonça,Vanessa Amaral
Lacerda,Ana Cristina Rodrigues
Nunes,Maria Carmo Pereira
Mediano,Mauro Felippe Felix
Rocha,Manoel Otávio da Costa
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Costa,Henrique Silveira
Lima,Márcia Maria Oliveira
Figueiredo,Pedro Henrique Scheidt
Lima,Vanessa Pereira
Ávila,Matheus Ribeiro
Menezes,Kenia Kiefer Parreiras de
Mendonça,Vanessa Amaral
Lacerda,Ana Cristina Rodrigues
Nunes,Maria Carmo Pereira
Mediano,Mauro Felippe Felix
Rocha,Manoel Otávio da Costa
dc.subject.por.fl_str_mv Chagas disease
Chagas cardiomyopathy
Exercise test
Exercise tolerance
Evaluation
Prognosis
topic Chagas disease
Chagas cardiomyopathy
Exercise test
Exercise tolerance
Evaluation
Prognosis
description Abstract Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases.
publishDate 2020
dc.date.none.fl_str_mv 2020-01-01
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dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv 10.1590/0037-8682-0100-2020
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.53 2020
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
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reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
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