Does a spontaneous cure for chagas' disease exist?
Autor(a) principal: | |
---|---|
Data de Publicação: | 1988 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Sociedade Brasileira de Medicina Tropical |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003 |
Resumo: | Six Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and ergometry, exceptfor one of them with an incomplete block of the right bundle branch. Also, no alterations of the oesophagus motility was detected manometrically except for another patient who presented a slight hypersensivity reaction to a pharmacological test (Mecholyl). Three out of six patients became serologically negative in 1981, remaining as such until 1986. Besides the conventional serology, the search of protective ("lytic") antibodies was also performed in 1985 and 1986, being completely negative in one of the "cured" patients and dubious in the other two. The hypothesis that these three patients had as spontaneous cure, based on the clinical, serological and parasitologica l findings is discussed. |
id |
SBMT-1_beb027cc27e7f36cb86b3a4fef143a18 |
---|---|
oai_identifier_str |
oai:scielo:S0037-86821988000100003 |
network_acronym_str |
SBMT-1 |
network_name_str |
Revista da Sociedade Brasileira de Medicina Tropical |
repository_id_str |
|
spelling |
Does a spontaneous cure for chagas' disease exist?American trypanosomiasisChagas' diseaseSpontaneous cureLongitudinal studiesSix Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and ergometry, exceptfor one of them with an incomplete block of the right bundle branch. Also, no alterations of the oesophagus motility was detected manometrically except for another patient who presented a slight hypersensivity reaction to a pharmacological test (Mecholyl). Three out of six patients became serologically negative in 1981, remaining as such until 1986. Besides the conventional serology, the search of protective ("lytic") antibodies was also performed in 1985 and 1986, being completely negative in one of the "cured" patients and dubious in the other two. The hypothesis that these three patients had as spontaneous cure, based on the clinical, serological and parasitologica l findings is discussed.Sociedade Brasileira de Medicina Tropical - SBMT1988-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003Revista da Sociedade Brasileira de Medicina Tropical v.21 n.1 1988reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86821988000100003info:eu-repo/semantics/openAccessZeledón,RodrigoDias,João Carlos P.Brilla-Salazar,A.Rezende,J. Marcondes deVargas,Luis G.Urbina,Andreaeng2013-05-29T00:00:00Zoai:scielo:S0037-86821988000100003Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2013-05-29T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Does a spontaneous cure for chagas' disease exist? |
title |
Does a spontaneous cure for chagas' disease exist? |
spellingShingle |
Does a spontaneous cure for chagas' disease exist? Zeledón,Rodrigo American trypanosomiasis Chagas' disease Spontaneous cure Longitudinal studies |
title_short |
Does a spontaneous cure for chagas' disease exist? |
title_full |
Does a spontaneous cure for chagas' disease exist? |
title_fullStr |
Does a spontaneous cure for chagas' disease exist? |
title_full_unstemmed |
Does a spontaneous cure for chagas' disease exist? |
title_sort |
Does a spontaneous cure for chagas' disease exist? |
author |
Zeledón,Rodrigo |
author_facet |
Zeledón,Rodrigo Dias,João Carlos P. Brilla-Salazar,A. Rezende,J. Marcondes de Vargas,Luis G. Urbina,Andrea |
author_role |
author |
author2 |
Dias,João Carlos P. Brilla-Salazar,A. Rezende,J. Marcondes de Vargas,Luis G. Urbina,Andrea |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Zeledón,Rodrigo Dias,João Carlos P. Brilla-Salazar,A. Rezende,J. Marcondes de Vargas,Luis G. Urbina,Andrea |
dc.subject.por.fl_str_mv |
American trypanosomiasis Chagas' disease Spontaneous cure Longitudinal studies |
topic |
American trypanosomiasis Chagas' disease Spontaneous cure Longitudinal studies |
description |
Six Costa Rican Chagas' disease patients, with wellknown acute phase history and no specific treatment were examined in several occasions during 39, 24, 32, 16 and 14 years, respectively, from the onset. Nome of the patients presented heart abnormalities as revealed by the conventional EKG and ergometry, exceptfor one of them with an incomplete block of the right bundle branch. Also, no alterations of the oesophagus motility was detected manometrically except for another patient who presented a slight hypersensivity reaction to a pharmacological test (Mecholyl). Three out of six patients became serologically negative in 1981, remaining as such until 1986. Besides the conventional serology, the search of protective ("lytic") antibodies was also performed in 1985 and 1986, being completely negative in one of the "cured" patients and dubious in the other two. The hypothesis that these three patients had as spontaneous cure, based on the clinical, serological and parasitologica l findings is discussed. |
publishDate |
1988 |
dc.date.none.fl_str_mv |
1988-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821988000100003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86821988000100003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.21 n.1 1988 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
_version_ |
1752122148656250880 |