Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018

Detalhes bibliográficos
Autor(a) principal: Sousa Jr,Ivanildo Pedro de
Data de Publicação: 2021
Outros Autores: Machado,Raiana Scerni, Burlandy,Fernanda Marcicano, Silva,Edson Elias da
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100701
Resumo: Abstract Although different etiological agents can cause acute meningoencephalitis, this syndrome is usually associated with viruses. Among these, enteroviruses play a significant role. Here, we describe a fatal case of meningoencephalitis in a previously healthy teenager. Real-time RT-PCR and cell culture assays were performed with serum and cerebrospinal fluid (CSF) from a clinically diagnosed meningoencephalitis case that occurred in Rio de Janeiro State, Brazil. Coxsackievirus B2 (CVB2) was identified. Phylogenetic analysis revealed that the identified CVB2 was genetically related to strains known to cause neurological diseases. This case highlights the importance of continuous laboratory surveillance of central nervous system infections.
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spelling Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018MeningoencephalitisEnterovirusCoxsackievirus B2Abstract Although different etiological agents can cause acute meningoencephalitis, this syndrome is usually associated with viruses. Among these, enteroviruses play a significant role. Here, we describe a fatal case of meningoencephalitis in a previously healthy teenager. Real-time RT-PCR and cell culture assays were performed with serum and cerebrospinal fluid (CSF) from a clinically diagnosed meningoencephalitis case that occurred in Rio de Janeiro State, Brazil. Coxsackievirus B2 (CVB2) was identified. Phylogenetic analysis revealed that the identified CVB2 was genetically related to strains known to cause neurological diseases. This case highlights the importance of continuous laboratory surveillance of central nervous system infections.Sociedade Brasileira de Medicina Tropical - SBMT2021-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100701Revista da Sociedade Brasileira de Medicina Tropical v.54 2021reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-0499-2019info:eu-repo/semantics/openAccessSousa Jr,Ivanildo Pedro deMachado,Raiana ScerniBurlandy,Fernanda MarcicanoSilva,Edson Elias daeng2020-11-10T00:00:00Zoai:scielo:S0037-86822021000100701Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2020-11-10T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
title Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
spellingShingle Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
Sousa Jr,Ivanildo Pedro de
Meningoencephalitis
Enterovirus
Coxsackievirus B2
title_short Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
title_full Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
title_fullStr Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
title_full_unstemmed Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
title_sort Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
author Sousa Jr,Ivanildo Pedro de
author_facet Sousa Jr,Ivanildo Pedro de
Machado,Raiana Scerni
Burlandy,Fernanda Marcicano
Silva,Edson Elias da
author_role author
author2 Machado,Raiana Scerni
Burlandy,Fernanda Marcicano
Silva,Edson Elias da
author2_role author
author
author
dc.contributor.author.fl_str_mv Sousa Jr,Ivanildo Pedro de
Machado,Raiana Scerni
Burlandy,Fernanda Marcicano
Silva,Edson Elias da
dc.subject.por.fl_str_mv Meningoencephalitis
Enterovirus
Coxsackievirus B2
topic Meningoencephalitis
Enterovirus
Coxsackievirus B2
description Abstract Although different etiological agents can cause acute meningoencephalitis, this syndrome is usually associated with viruses. Among these, enteroviruses play a significant role. Here, we describe a fatal case of meningoencephalitis in a previously healthy teenager. Real-time RT-PCR and cell culture assays were performed with serum and cerebrospinal fluid (CSF) from a clinically diagnosed meningoencephalitis case that occurred in Rio de Janeiro State, Brazil. Coxsackievirus B2 (CVB2) was identified. Phylogenetic analysis revealed that the identified CVB2 was genetically related to strains known to cause neurological diseases. This case highlights the importance of continuous laboratory surveillance of central nervous system infections.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100701
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0037-8682-0499-2019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.54 2021
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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