Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy

Detalhes bibliográficos
Autor(a) principal: Covre,Lúcia Carla Polaco
Data de Publicação: 2018
Outros Autores: Hombre,Pâmela Mazzini, Falqueto,Aloísio, Peçanha,Paulo Mendes, Valim,Valéria
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200249
Resumo: Abstract Paracoccidioidomycosis is an endemic disease in Latin America that is rarely associated with immunosuppression and biological therapy. Herein, we report for the first time a case of pulmonary paracoccidioidomycosis reactivation after infliximab treatment. A 47-year-old man from Brazil received infliximab to treat psoriatic spondyloarthropathy and presented with cough, dyspnea, weight loss, and fever. Chest computed tomography revealed a pulmonary nodule and biopsy confirmed paracoccidioidomycosis. Treatment with sulfamethoxazole and trimethoprim was initiated for fungal infection and infliximab was reintroduced two months later. Considering his clinical improvement and favorable radiologic evolution, antifungal therapy was discontinued after 29 months.
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spelling Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapyParacoccidioidomycosisInfliximabImmunosuppressionAbstract Paracoccidioidomycosis is an endemic disease in Latin America that is rarely associated with immunosuppression and biological therapy. Herein, we report for the first time a case of pulmonary paracoccidioidomycosis reactivation after infliximab treatment. A 47-year-old man from Brazil received infliximab to treat psoriatic spondyloarthropathy and presented with cough, dyspnea, weight loss, and fever. Chest computed tomography revealed a pulmonary nodule and biopsy confirmed paracoccidioidomycosis. Treatment with sulfamethoxazole and trimethoprim was initiated for fungal infection and infliximab was reintroduced two months later. Considering his clinical improvement and favorable radiologic evolution, antifungal therapy was discontinued after 29 months.Sociedade Brasileira de Medicina Tropical - SBMT2018-04-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200249Revista da Sociedade Brasileira de Medicina Tropical v.51 n.2 2018reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-0222-2017info:eu-repo/semantics/openAccessCovre,Lúcia Carla PolacoHombre,Pâmela MazziniFalqueto,AloísioPeçanha,Paulo MendesValim,Valériaeng2018-05-11T00:00:00Zoai:scielo:S0037-86822018000200249Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2018-05-11T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
title Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
spellingShingle Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
Covre,Lúcia Carla Polaco
Paracoccidioidomycosis
Infliximab
Immunosuppression
title_short Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
title_full Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
title_fullStr Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
title_full_unstemmed Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
title_sort Pulmonary paracoccidioidomycosis: a case report of reactivation in a patient receiving biological therapy
author Covre,Lúcia Carla Polaco
author_facet Covre,Lúcia Carla Polaco
Hombre,Pâmela Mazzini
Falqueto,Aloísio
Peçanha,Paulo Mendes
Valim,Valéria
author_role author
author2 Hombre,Pâmela Mazzini
Falqueto,Aloísio
Peçanha,Paulo Mendes
Valim,Valéria
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Covre,Lúcia Carla Polaco
Hombre,Pâmela Mazzini
Falqueto,Aloísio
Peçanha,Paulo Mendes
Valim,Valéria
dc.subject.por.fl_str_mv Paracoccidioidomycosis
Infliximab
Immunosuppression
topic Paracoccidioidomycosis
Infliximab
Immunosuppression
description Abstract Paracoccidioidomycosis is an endemic disease in Latin America that is rarely associated with immunosuppression and biological therapy. Herein, we report for the first time a case of pulmonary paracoccidioidomycosis reactivation after infliximab treatment. A 47-year-old man from Brazil received infliximab to treat psoriatic spondyloarthropathy and presented with cough, dyspnea, weight loss, and fever. Chest computed tomography revealed a pulmonary nodule and biopsy confirmed paracoccidioidomycosis. Treatment with sulfamethoxazole and trimethoprim was initiated for fungal infection and infliximab was reintroduced two months later. Considering his clinical improvement and favorable radiologic evolution, antifungal therapy was discontinued after 29 months.
publishDate 2018
dc.date.none.fl_str_mv 2018-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200249
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200249
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0037-8682-0222-2017
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.51 n.2 2018
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
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instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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