Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar
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Publication Date: | 2000 |
Other Authors: | , , , , , |
Format: | Article |
Language: | eng |
Source: | Revista da Sociedade Brasileira de Medicina Tropical |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005 |
Summary: | Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients without detectable bone marrow fibrosis (wbmf = 18). There were no significant differences in clinical and blood parameters following treatment. All patients showed regression of hepatosplenomegaly.Our findings suggest that associated bone marrow fibrosis is transient and did not interfere in the evolution of treated patients. |
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Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azarHuman kala-azarMyelofibrosisBone marrow biopsyThirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients without detectable bone marrow fibrosis (wbmf = 18). There were no significant differences in clinical and blood parameters following treatment. All patients showed regression of hepatosplenomegaly.Our findings suggest that associated bone marrow fibrosis is transient and did not interfere in the evolution of treated patients.Sociedade Brasileira de Medicina Tropical - SBMT2000-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005Revista da Sociedade Brasileira de Medicina Tropical v.33 n.4 2000reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822000000400005info:eu-repo/semantics/openAccessRocha Filho,Francisco DárioFerreira,Francisco Valdeci de AlmeidaMendes,Flávia de OliveiraFerreira,Fernanda Nogueira HolandaKarbage,AlexandreAlencar,Marília LageCosta,Danielleeng2000-08-24T00:00:00Zoai:scielo:S0037-86822000000400005Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2000-08-24T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
spellingShingle |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar Rocha Filho,Francisco Dário Human kala-azar Myelofibrosis Bone marrow biopsy |
title_short |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_full |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_fullStr |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_full_unstemmed |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
title_sort |
Bone marrow fibrosis (pseudo-myelofibrosis) in human kala-azar |
author |
Rocha Filho,Francisco Dário |
author_facet |
Rocha Filho,Francisco Dário Ferreira,Francisco Valdeci de Almeida Mendes,Flávia de Oliveira Ferreira,Fernanda Nogueira Holanda Karbage,Alexandre Alencar,Marília Lage Costa,Danielle |
author_role |
author |
author2 |
Ferreira,Francisco Valdeci de Almeida Mendes,Flávia de Oliveira Ferreira,Fernanda Nogueira Holanda Karbage,Alexandre Alencar,Marília Lage Costa,Danielle |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Rocha Filho,Francisco Dário Ferreira,Francisco Valdeci de Almeida Mendes,Flávia de Oliveira Ferreira,Fernanda Nogueira Holanda Karbage,Alexandre Alencar,Marília Lage Costa,Danielle |
dc.subject.por.fl_str_mv |
Human kala-azar Myelofibrosis Bone marrow biopsy |
topic |
Human kala-azar Myelofibrosis Bone marrow biopsy |
description |
Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients without detectable bone marrow fibrosis (wbmf = 18). There were no significant differences in clinical and blood parameters following treatment. All patients showed regression of hepatosplenomegaly.Our findings suggest that associated bone marrow fibrosis is transient and did not interfere in the evolution of treated patients. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86822000000400005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.33 n.4 2000 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
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1752122151125647360 |