Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Medicine |
Texto Completo: | https://rbmv.org/BJVM/article/view/243 |
Resumo: | ABSTRACT. Cabala R.W., Silva E.B. & Clark R.M.O. [Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs.] Avaliação cardiorrespiratória, qualidade de indução e intubação orotraqueal com o uso de coadjuvantes na indução anestésica com propofol em cães. Revista Brasileira de Medicina Veterinária, 38(1):39-44, 2016. Escola de Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Caixa Postal 1567, Campus Pampulha, Belo Horizonte, MG 31270-901, Brasil. E-mail: raquelcabala@yahoo.com.br The objective was to evaluate the effects of the use of fentanyl, ketamine or diazepam, as coadjuvant induction of anesthesia with propofol in dogs and to evaluate the cardiovascular, respiratory and quality of induction of anesthesia and tracheal intubation by these agents. Twenty four dogs ASA I and II, of different breeds and average weight 18 ± 6.8 kg, males and females subjected to different surgical procedures were randomly allocated in four groups of six each: G-CP (saline); G-FP (5mcg/kg - fentanyl), G-KP (0,5 mg/kg - ketamine) and G-DP (0,2mg/kg - diazepam). All animals recieved pre-anaesthetic medication with acepromazine (0,05 mg/kg) combined with morphine (0,2 mg/kg) administered intramuscularly. Two minutes after coadjuvants or saline administration, the anaesthetic induction was perfomed with 5mg/kg of propofol or the sufficient dose required to lost protector reflex and ensure endotracheal intubation. HR, SAP, MAP, DAP, RR, ETCO2, SpO2, and To C were measured before pre-anaesthetic medication (M1), 15 minutes after M1 (M2), during induction of anesthesia (M3), at the end of induction anesthetic (M4) and after intubation (M5). The quality of anesthesia was evaluated using a numerical scale by induction and intubation score. The use of fentanyl as co-adjuvant induction reduced significantly propofol dose requirement (2,42±0,38mg/kg), when compared to G-CP (4,43±0,32mg/kg), to G-DP (3,78±1,3mg/kg) and to G-KP (3,90±0,84mg/kg). Significant reductions on arterial pressures ocurred in G-FP, but it were similar in G-CP. No statistically significant differences were observed between groups in mean HR, RR, ETCO2 , SpO2 and To C. SpO2 was reduced in M4 of G-DP. The induction and intubation scores were similar in all groups. The administration of fentanyl decreased propofol requirement but promoted severe hypotension when compared with other co-adjuvants agents. There were minimal undesirable effects. The quality of induction and intubation were satisfactory, but the dogs that were induced with only propofol demonstrated better score. |
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Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogsAvaliação cardiorrespiratória, qualidade de indução e intubação orotraqueal com o uso de coadjuvantes na indução anestésica com propofol em cãesPropofolcoadjuvantesindução anestésicacãesPropofolcoadjuvantsanaesthesia inductiondogsABSTRACT. Cabala R.W., Silva E.B. & Clark R.M.O. [Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs.] Avaliação cardiorrespiratória, qualidade de indução e intubação orotraqueal com o uso de coadjuvantes na indução anestésica com propofol em cães. Revista Brasileira de Medicina Veterinária, 38(1):39-44, 2016. Escola de Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Caixa Postal 1567, Campus Pampulha, Belo Horizonte, MG 31270-901, Brasil. E-mail: raquelcabala@yahoo.com.br The objective was to evaluate the effects of the use of fentanyl, ketamine or diazepam, as coadjuvant induction of anesthesia with propofol in dogs and to evaluate the cardiovascular, respiratory and quality of induction of anesthesia and tracheal intubation by these agents. Twenty four dogs ASA I and II, of different breeds and average weight 18 ± 6.8 kg, males and females subjected to different surgical procedures were randomly allocated in four groups of six each: G-CP (saline); G-FP (5mcg/kg - fentanyl), G-KP (0,5 mg/kg - ketamine) and G-DP (0,2mg/kg - diazepam). All animals recieved pre-anaesthetic medication with acepromazine (0,05 mg/kg) combined with morphine (0,2 mg/kg) administered intramuscularly. Two minutes after coadjuvants or saline administration, the anaesthetic induction was perfomed with 5mg/kg of propofol or the sufficient dose required to lost protector reflex and ensure endotracheal intubation. HR, SAP, MAP, DAP, RR, ETCO2, SpO2, and To C were measured before pre-anaesthetic medication (M1), 15 minutes after M1 (M2), during induction of anesthesia (M3), at the end of induction anesthetic (M4) and after intubation (M5). The quality of anesthesia was evaluated using a numerical scale by induction and intubation score. The use of fentanyl as co-adjuvant induction reduced significantly propofol dose requirement (2,42±0,38mg/kg), when compared to G-CP (4,43±0,32mg/kg), to G-DP (3,78±1,3mg/kg) and to G-KP (3,90±0,84mg/kg). Significant reductions on arterial pressures ocurred in G-FP, but it were similar in G-CP. No statistically significant differences were observed between groups in mean HR, RR, ETCO2 , SpO2 and To C. SpO2 was reduced in M4 of G-DP. The induction and intubation scores were similar in all groups. The administration of fentanyl decreased propofol requirement but promoted severe hypotension when compared with other co-adjuvants agents. There were minimal undesirable effects. The quality of induction and intubation were satisfactory, but the dogs that were induced with only propofol demonstrated better score.Objetivou-se avaliar os efeitos cardiorrespiratórios e qualidade de indução do uso do fentanil, quetamina ou diazepam como coadjuvantes da indução anestésica pelo propofol em cães. Foram utilizados 24 cães ASA I e II, de diferentes raças, machos e fêmeas, com peso médio 18±6,8kg, submetidos a diferentes procedimentos cirúrgicos, distribuídos aleatoriamente em quatro grupos de seis animais cada: G-CP (solução salina e propofol); G-FP (5 mcg.kg-1 de fentanil e propofol), G-KP (0,5 mg.kg-1 de quetamina e propofol) e G-DP (0,2mg. kg-1 de diazepam e propofol). Os animais foram pré- -medicados com acepromazina (0,05 mg.kg-1) e morfina (0,2 mg.kg-1), pela via intramuscular. A indução anestésica foi realizada com 5mg.kg-1 de propofol ou aquela suficiente para abolir o reflexo laringotraqueal para realização da intubação orotraqueal. Dois minutos antes do propofol foi administrado o agente coadjuvante ou solução salina conforme os grupos estudados. Avaliaram-se a FC, PAS, PAM, PAD, f, ETCO2, SatO2,e To C que foram mensuradas antes da MPA (M1), 15 minutos após MPA (M2), durante a indução anestésica (M3), ao término da indução anestésica (M4) e após a intubação endotraqueal (M5). A qualidade da indução anestésica foi avaliada através de uma escala numérica denominada escore de indução e intubação. Os coadjuvantes ou a salina foram administrados dois minutos previamente a indução com propofol (5mg.kg-1) até a abolição dos reflexos protetores e intubação orotraqueal. O uso do fentanil como coadjuvantes reduziu a dose do propofol em relação aos demais coadjuvantes e o grupo controle. Além disso, proporcionou redução significativa da pressão arterial, porém de magnitude semelhante ao grupo salina-propofol. Não foram observadas diferenças significativas entre os tratamentos para FC, f, ETCO2 e To C. A SatO2 apresentou redução em M4 no G-DP. A qualidade da indução anestésica foi similar e satisfatória para todos os grupos, não apresentando diferença significativa. O fentanil proporcionou maior redução da dose do propofol, resultando em hipotensão mais severa em relação aos demais agentes coadjuvantes. Os efeitos colaterais foram mínimos. A qualidade de indução e intubação foram similares e satisfatórias, porém os animais que receberam apenas propofol apresentaram os melhores escores.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2016-03-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/24310.2430/00000000000000Brazilian Journal of Veterinary Medicine; Vol. 38 No. 1 (2016); 39-44Revista Brasileira de Medicina Veterinária; v. 38 n. 1 (2016); 39-442527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/243/164Cabala, Raquel Wolffda Silva, Elisângela BarbozaClark, Rosana Maria de Oliveirainfo:eu-repo/semantics/openAccess2020-12-23T17:26:24Zoai:ojs.rbmv.org:article/243Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:26:24Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
dc.title.none.fl_str_mv |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs Avaliação cardiorrespiratória, qualidade de indução e intubação orotraqueal com o uso de coadjuvantes na indução anestésica com propofol em cães |
title |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
spellingShingle |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs Cabala, Raquel Wolff Propofol coadjuvantes indução anestésica cães Propofol coadjuvants anaesthesia induction dogs |
title_short |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
title_full |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
title_fullStr |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
title_full_unstemmed |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
title_sort |
Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs |
author |
Cabala, Raquel Wolff |
author_facet |
Cabala, Raquel Wolff da Silva, Elisângela Barboza Clark, Rosana Maria de Oliveira |
author_role |
author |
author2 |
da Silva, Elisângela Barboza Clark, Rosana Maria de Oliveira |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Cabala, Raquel Wolff da Silva, Elisângela Barboza Clark, Rosana Maria de Oliveira |
dc.subject.por.fl_str_mv |
Propofol coadjuvantes indução anestésica cães Propofol coadjuvants anaesthesia induction dogs |
topic |
Propofol coadjuvantes indução anestésica cães Propofol coadjuvants anaesthesia induction dogs |
description |
ABSTRACT. Cabala R.W., Silva E.B. & Clark R.M.O. [Cardiopulmonary assessment, quality induction and tracheal intubation with the use of induction adjunct with propofol in dogs.] Avaliação cardiorrespiratória, qualidade de indução e intubação orotraqueal com o uso de coadjuvantes na indução anestésica com propofol em cães. Revista Brasileira de Medicina Veterinária, 38(1):39-44, 2016. Escola de Veterinária, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Caixa Postal 1567, Campus Pampulha, Belo Horizonte, MG 31270-901, Brasil. E-mail: raquelcabala@yahoo.com.br The objective was to evaluate the effects of the use of fentanyl, ketamine or diazepam, as coadjuvant induction of anesthesia with propofol in dogs and to evaluate the cardiovascular, respiratory and quality of induction of anesthesia and tracheal intubation by these agents. Twenty four dogs ASA I and II, of different breeds and average weight 18 ± 6.8 kg, males and females subjected to different surgical procedures were randomly allocated in four groups of six each: G-CP (saline); G-FP (5mcg/kg - fentanyl), G-KP (0,5 mg/kg - ketamine) and G-DP (0,2mg/kg - diazepam). All animals recieved pre-anaesthetic medication with acepromazine (0,05 mg/kg) combined with morphine (0,2 mg/kg) administered intramuscularly. Two minutes after coadjuvants or saline administration, the anaesthetic induction was perfomed with 5mg/kg of propofol or the sufficient dose required to lost protector reflex and ensure endotracheal intubation. HR, SAP, MAP, DAP, RR, ETCO2, SpO2, and To C were measured before pre-anaesthetic medication (M1), 15 minutes after M1 (M2), during induction of anesthesia (M3), at the end of induction anesthetic (M4) and after intubation (M5). The quality of anesthesia was evaluated using a numerical scale by induction and intubation score. The use of fentanyl as co-adjuvant induction reduced significantly propofol dose requirement (2,42±0,38mg/kg), when compared to G-CP (4,43±0,32mg/kg), to G-DP (3,78±1,3mg/kg) and to G-KP (3,90±0,84mg/kg). Significant reductions on arterial pressures ocurred in G-FP, but it were similar in G-CP. No statistically significant differences were observed between groups in mean HR, RR, ETCO2 , SpO2 and To C. SpO2 was reduced in M4 of G-DP. The induction and intubation scores were similar in all groups. The administration of fentanyl decreased propofol requirement but promoted severe hypotension when compared with other co-adjuvants agents. There were minimal undesirable effects. The quality of induction and intubation were satisfactory, but the dogs that were induced with only propofol demonstrated better score. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-03-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer reviewed Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/243 10.2430/00000000000000 |
url |
https://rbmv.org/BJVM/article/view/243 |
identifier_str_mv |
10.2430/00000000000000 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/243/164 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 38 No. 1 (2016); 39-44 Revista Brasileira de Medicina Veterinária; v. 38 n. 1 (2016); 39-44 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
instname_str |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
instacron_str |
SBMV |
institution |
SBMV |
reponame_str |
Brazilian Journal of Veterinary Medicine |
collection |
Brazilian Journal of Veterinary Medicine |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
repository.mail.fl_str_mv |
contato.rbmv@gmail.com |
_version_ |
1798313107009830912 |