AFLATOXIN B1 RESIDUES IN LIVER OF JAPANESE QUAIL (Coturnix japonica) EXPOSED TO CONTAMINATED FEED AND EXOGENOUS CORTICOSTERONE

• Autor(a) principal: Magnoli, Alejandra Paola
• Data de Publicação: 2013
• Outros Autores: Chiacchiera, Stella x Stella Maris, Rosa, Carlos Alberto da Rocha, Dalcero, Ana Maria
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Veterinary Medicine
• Texto Completo: https://rbmv.org/BJVM/article/view/636
• topic: Corticosterona; codornas japonesas; fígado; aflatoxina B1; Aflatoxicosis; corticosterone; stress response; Japanese quail; liver; Aflatoxin B1 residues

R.H. Aflatoxin B1 residues in liver of Japanese quail (Coturnix japonica) exposed to contaminated feed and exogenous corticosterone. [Resíduos de aflatoxina B1 em fígado de codornas japonesas (Coturnix japonica) expostas a alimentos contaminados e à corticosterona exógena]. Revista Brasileira de Medicina Veterinária, 35(4):378-384, 2013. Departamento de Química, Universidad Nacional de Rio Cuarto, Rio Cuarto, Córdoba, Argentina. E-mail: [e-mail] The combined effect of aflatoxin B1 (AFB1 ) exposition and stress induced by corticosterone (CORT) upon the residual aflatoxin levels in livers of Japanese quail was examined. A total of 144 Japanese quail (Coturnix japonica) were divided into 6 treatments with 6 replicates per treatment, each containing 2 males and 2 females. The different treatments resulted from the combination of the presence or absence of CORT in drinking water (5 mg/L) with the presence or absence of AFB1 supplementation (100 or 500 ng/g). Dietary treatments were offered from 5 to 11 weeks of age. The different diets were: Treatment (T) 1: basal diet (B) AFB1 (15 ng/g); T2: B plus AFB1 (100 ng/g); T3: B plus AFB1 (500 ng/g); T4: B plus CORT (5 mg/L); T5: B plus AFB1 (100 ng/g) and CORT (5 mg/L); and T6: B plus AFB1 (500 ng/g) and CORT (5 mg/L). The residual levels of AFB1 were remarkably higher in livers of birds fed with AFB1 in comparison with those belonging to the group that received a combination of AFB1 and CORT (P< 0.05). A plausible explanation about the facts that could be responsible for observed reduction in the toxin carryover in liver was suggested. These results are very striking and may constitute the start point for a series of studies that aim to elucidate the precise influence of hypothalamic-pituitary-adrenal axis (HPA) response to stress in birds exposed to AFB1.