Mammalian yolk sac - an alternative source of stem cells
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Brazilian Journal of Veterinary Medicine |
| Texto Completo: | https://rbmv.org/BJVM/article/view/1179 |
Resumo: | Fetal tissue-derived stem cells have been the subject of several studies. Among them, the yolk sac (YS) nourishes the embryo, synthesizes proteins and vitamins, and is the first hematopoietic site of the embryo. Stem cells derived from the YS can benefit several animal species as therapies aimed at tissue regeneration and immunological diseases. This review aims to describe the development, function, and possible dysfunctions of YS in different species, and consolidate the findings presented in the literature on the isolation, culture, and application of YS-derived stem cells from different mammals in regenerative medicine. Hematopoietic and mesenchymal stem cells have been previously investigated in the YS of different mammals; however, the culture media and isolation protocols differ between species. To date, no studies have been conducted using stem cells derived from the YS for cell therapy. Nevertheless, several domestic mammals have shown cellular markers characteristic of mesenchymal stem cells derived from the YS. |
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Mammalian yolk sac - an alternative source of stem cellsSaco vitelino de mamíferos - uma fonte alternativa de células-troncoPalavras-chave: células-tronco mesenquimais, células-tronco hematopoéticas, desenvolvimento placentário, membranas fetais.mesenchymal stem cells, hematopoietic stem cells, placenta development, fetal membranes. Fetal tissue-derived stem cells have been the subject of several studies. Among them, the yolk sac (YS) nourishes the embryo, synthesizes proteins and vitamins, and is the first hematopoietic site of the embryo. Stem cells derived from the YS can benefit several animal species as therapies aimed at tissue regeneration and immunological diseases. This review aims to describe the development, function, and possible dysfunctions of YS in different species, and consolidate the findings presented in the literature on the isolation, culture, and application of YS-derived stem cells from different mammals in regenerative medicine. Hematopoietic and mesenchymal stem cells have been previously investigated in the YS of different mammals; however, the culture media and isolation protocols differ between species. To date, no studies have been conducted using stem cells derived from the YS for cell therapy. Nevertheless, several domestic mammals have shown cellular markers characteristic of mesenchymal stem cells derived from the YS.As células-tronco derivadas dos tecidos fetais têm sido objeto de vários estudos, entre elas, o saco vitelino (SV) tem a função de nutrir o embrião, sintetizar proteínas e vitaminas, sendo também o primeiro sítio hematopoiético do embrião. Além disso, o estudo de células tronco derivadas do saco vitelino favorece diversas espécies animais, tanto para terapias que buscam a regeneração de tecidos quanto para doenças imunológicas. Assim, esta revisão tem como objetivo descrever o desenvolvimento, função e possíveis disfunções do SV em diferentes espécies de mamíferos, bem como agrupar os resultados já obtidos na literatura sobre o isolamento, cultivo e aplicação de células tronco derivadas do SV. Sabe-se que o saco vitelino apresenta células tronco hematopoiéticas, além da presença de células-tronco mesenquimais em diferentes espécies, entretanto, os meios de cultura e os protocolos de isolamento diferem entre as espécies. Até o momento, nenhum estudo foi encontrado usando células tronco derivadas do saco vitelino para terapia celular, no entanto, vários mamíferos domésticos mostraram marcadores celulares característicos de células tronco mesenquimais derivadas do saco vitelino.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2021-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelated ArticlesArtigo de Connvidadoapplication/pdftext/xmlhttps://rbmv.org/BJVM/article/view/117910.29374/2527-2179.bjvm001221Brazilian Journal of Veterinary Medicine; Vol. 43 No. 1 (2021); e001221Revista Brasileira de Medicina Veterinária; v. 43 n. 1 (2021); e0012212527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVenghttps://rbmv.org/BJVM/article/view/1179/1087https://rbmv.org/BJVM/article/view/1179/1196Copyright (c) 2021 Priscilla Avelino Ferreira Pinto, Vitória Mattos Pereira, Lina Castelo Branco Motta, Matheus Ferreira de Almeida, Tiago Gonçalves dos Santos, Vanessa Cristina Oliveira, Luciana Cristina Machado, Carlos Eduardo Ambrósiohttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Pinto, Priscilla Avelino FerreiraPereira, Vitória Mattos Motta, Lina Castelo Branco de Almeida, Matheus Ferreira dos Santos, Tiago Gonçalves Oliveira, Vanessa Cristina Machado, Luciana Cristina Ambrósio, Carlos Eduardo 2022-06-26T20:51:10Zoai:ojs.rbmv.org:article/1179Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2022-06-26T20:51:10Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
| dc.title.none.fl_str_mv |
Mammalian yolk sac - an alternative source of stem cells Saco vitelino de mamíferos - uma fonte alternativa de células-tronco |
| title |
Mammalian yolk sac - an alternative source of stem cells |
| spellingShingle |
Mammalian yolk sac - an alternative source of stem cells Pinto, Priscilla Avelino Ferreira Palavras-chave: células-tronco mesenquimais, células-tronco hematopoéticas, desenvolvimento placentário, membranas fetais. mesenchymal stem cells, hematopoietic stem cells, placenta development, fetal membranes. |
| title_short |
Mammalian yolk sac - an alternative source of stem cells |
| title_full |
Mammalian yolk sac - an alternative source of stem cells |
| title_fullStr |
Mammalian yolk sac - an alternative source of stem cells |
| title_full_unstemmed |
Mammalian yolk sac - an alternative source of stem cells |
| title_sort |
Mammalian yolk sac - an alternative source of stem cells |
| author |
Pinto, Priscilla Avelino Ferreira |
| author_facet |
Pinto, Priscilla Avelino Ferreira Pereira, Vitória Mattos Motta, Lina Castelo Branco de Almeida, Matheus Ferreira dos Santos, Tiago Gonçalves Oliveira, Vanessa Cristina Machado, Luciana Cristina Ambrósio, Carlos Eduardo |
| author_role |
author |
| author2 |
Pereira, Vitória Mattos Motta, Lina Castelo Branco de Almeida, Matheus Ferreira dos Santos, Tiago Gonçalves Oliveira, Vanessa Cristina Machado, Luciana Cristina Ambrósio, Carlos Eduardo |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pinto, Priscilla Avelino Ferreira Pereira, Vitória Mattos Motta, Lina Castelo Branco de Almeida, Matheus Ferreira dos Santos, Tiago Gonçalves Oliveira, Vanessa Cristina Machado, Luciana Cristina Ambrósio, Carlos Eduardo |
| dc.subject.por.fl_str_mv |
Palavras-chave: células-tronco mesenquimais, células-tronco hematopoéticas, desenvolvimento placentário, membranas fetais. mesenchymal stem cells, hematopoietic stem cells, placenta development, fetal membranes. |
| topic |
Palavras-chave: células-tronco mesenquimais, células-tronco hematopoéticas, desenvolvimento placentário, membranas fetais. mesenchymal stem cells, hematopoietic stem cells, placenta development, fetal membranes. |
| description |
Fetal tissue-derived stem cells have been the subject of several studies. Among them, the yolk sac (YS) nourishes the embryo, synthesizes proteins and vitamins, and is the first hematopoietic site of the embryo. Stem cells derived from the YS can benefit several animal species as therapies aimed at tissue regeneration and immunological diseases. This review aims to describe the development, function, and possible dysfunctions of YS in different species, and consolidate the findings presented in the literature on the isolation, culture, and application of YS-derived stem cells from different mammals in regenerative medicine. Hematopoietic and mesenchymal stem cells have been previously investigated in the YS of different mammals; however, the culture media and isolation protocols differ between species. To date, no studies have been conducted using stem cells derived from the YS for cell therapy. Nevertheless, several domestic mammals have shown cellular markers characteristic of mesenchymal stem cells derived from the YS. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-06-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Related Articles Artigo de Connvidado |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/1179 10.29374/2527-2179.bjvm001221 |
| url |
https://rbmv.org/BJVM/article/view/1179 |
| identifier_str_mv |
10.29374/2527-2179.bjvm001221 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/1179/1087 https://rbmv.org/BJVM/article/view/1179/1196 |
| dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf text/xml |
| dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
| publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
| dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 43 No. 1 (2021); e001221 Revista Brasileira de Medicina Veterinária; v. 43 n. 1 (2021); e001221 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
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Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
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SBMV |
| institution |
SBMV |
| reponame_str |
Brazilian Journal of Veterinary Medicine |
| collection |
Brazilian Journal of Veterinary Medicine |
| repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
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contato.rbmv@gmail.com |
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1798313110788898816 |