Poisoning by methylene blue (methylthioninium chloride) in cat
Autor(a) principal: | |
---|---|
Data de Publicação: | 2016 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Medicine |
Texto Completo: | https://rbmv.org/BJVM/article/view/196 |
Resumo: | ABSTRACT. Costa S.Z.R., Cid G.C., D’Avila M.S., França T.N., Santos B.B.N., Nogueira V.A., Santos A.M. & Peixoto T.C. [Poisoning by methylene blue (methylthioninium chloride) in cat.] Intoxicação por azul de metileno (cloreto de metiltionínio) em gato. Revista Brasileira de Medicina Veterinária, 38(Supl.2):143- 146, 2016. Departamento de Epidemiologia e Saúde Pública, Universidade Federal Rural do Rio de Janeiro, Campus de Seropédica, Rodovia BR 465 Km 7, Seropédica, RJ 23851-970, Brasil. E-mail: vivianmedvet@yahoo.com.br It’s reported a case of poisoning by methylene blue (methylthioniniumchloride) in cat that was sent to the Pathological Anatomy Sector of UFRRJ in October 2011, with history of urinary tract infection. By means of necropsy, mucous, subcutaneous tissue, medullary region of the kidney, serous bladder and adjacent tissues to the bladder with clear bluish tint, disclosure of hepatic lobular pattern, additionally bladder mucosa bluishand urine with sediments, blackened and foul odor were observed. Histopathological analysis showed micro and macrovesicular vacuolation of hepatocytes, overall in centrilobular region, which could extend to midzonal lobule region; some cells were lysed. There was, additionally, individual necrosis of rare hepatocytes and biliary retention, increase of the filtrate in tubules and glomeruli, with dilation of Bowman’s capsule, vacuolized tubular epithelium and thickening of the glomerular basement membrane. There was coagulation necrosis in some tubules of the medular area and small quantity of yellow-brown pigment in the cytoplasm of the tubular epithelium. The diagnosis of poisoning by methylene blue (methylthioninium chloride) was established based on the animal’s history and the clinical and pathological findings. |
id |
SBMV-1_ab62d1748b567721d5c25c4ff76b84cf |
---|---|
oai_identifier_str |
oai:ojs.rbmv.org:article/196 |
network_acronym_str |
SBMV-1 |
network_name_str |
Brazilian Journal of Veterinary Medicine |
repository_id_str |
|
spelling |
Poisoning by methylene blue (methylthioninium chloride) in catIntoxicação por azul de metileno (cloreto de metiltionínio) em gatoToxicosefelinoazul de metilenoToxicosisfelinemethylene blueABSTRACT. Costa S.Z.R., Cid G.C., D’Avila M.S., França T.N., Santos B.B.N., Nogueira V.A., Santos A.M. & Peixoto T.C. [Poisoning by methylene blue (methylthioninium chloride) in cat.] Intoxicação por azul de metileno (cloreto de metiltionínio) em gato. Revista Brasileira de Medicina Veterinária, 38(Supl.2):143- 146, 2016. Departamento de Epidemiologia e Saúde Pública, Universidade Federal Rural do Rio de Janeiro, Campus de Seropédica, Rodovia BR 465 Km 7, Seropédica, RJ 23851-970, Brasil. E-mail: vivianmedvet@yahoo.com.br It’s reported a case of poisoning by methylene blue (methylthioniniumchloride) in cat that was sent to the Pathological Anatomy Sector of UFRRJ in October 2011, with history of urinary tract infection. By means of necropsy, mucous, subcutaneous tissue, medullary region of the kidney, serous bladder and adjacent tissues to the bladder with clear bluish tint, disclosure of hepatic lobular pattern, additionally bladder mucosa bluishand urine with sediments, blackened and foul odor were observed. Histopathological analysis showed micro and macrovesicular vacuolation of hepatocytes, overall in centrilobular region, which could extend to midzonal lobule region; some cells were lysed. There was, additionally, individual necrosis of rare hepatocytes and biliary retention, increase of the filtrate in tubules and glomeruli, with dilation of Bowman’s capsule, vacuolized tubular epithelium and thickening of the glomerular basement membrane. There was coagulation necrosis in some tubules of the medular area and small quantity of yellow-brown pigment in the cytoplasm of the tubular epithelium. The diagnosis of poisoning by methylene blue (methylthioninium chloride) was established based on the animal’s history and the clinical and pathological findings.Relata-se um caso de intoxicação por azul de metileno (cloreto de metiltionínio) em um felino doméstico (Felis catus) encaminhado para o Setor de Anatomia Patológica da Universidade Federal Rural do Rio de Janeiro em outubro de 2011 com histórico de infecção urinária. À necropsia, observaram-se mucosas, tecido subcutâneo, região medular do rim, serosa e mucosa da bexiga, além de tecidos adjacentes com nítida tonalidade azulada, notou-se ainda evidenciação do padrão lobular hepático, urina enegrecida com sedimentos e odor fétido. O exame histopatológico exibiu, vacuolização micro e macrovesicular de hepatócitos, sobretudo da região centro-lobular que, por vezes, estendia-se até a região intermediária do lóbulo; algumas células encontravam-se lisadas. Havia adicionalmente necrose individual de raros hepatócitos e retenção biliar, aumento de filtrado nos túbulos e glomérulos, com dilatação da cápsula de Bowman, epitélio tubular vacuolizado (mais que o normal para a espécie) e espessamento da membrana basal glomerular nos rins, além de necrose de coagulação em alguns túbulos da região medular e pequena quantidade de pigmento amarelo- -amarronzado no citoplasma do epitélio tubular. O diagnóstico de intoxicação por azul de metileno (cloreto de metiltionínio) foi estabelecido com base no histórico do animal e nos achados clínico-patológicos.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2016-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/196Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl.2 (2016); 145-148Revista Brasileira de Medicina Veterinária; v. 38 n. Supl.2 (2016); 145-1482527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/196/126Costa, Samay Zillmann RochaCid, Gabriela de CarvalhoD’Avila, Mariana SequeiraFrança, Ticiana Nascimentodos Santos, Bartolomeu Benedito NevesNogueira, Vivian de Assunçãodos Santos, André MarandolaPeixoto, Tiago da Cunhainfo:eu-repo/semantics/openAccess2020-12-23T17:34:13Zoai:ojs.rbmv.org:article/196Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:34:13Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
dc.title.none.fl_str_mv |
Poisoning by methylene blue (methylthioninium chloride) in cat Intoxicação por azul de metileno (cloreto de metiltionínio) em gato |
title |
Poisoning by methylene blue (methylthioninium chloride) in cat |
spellingShingle |
Poisoning by methylene blue (methylthioninium chloride) in cat Costa, Samay Zillmann Rocha Toxicose felino azul de metileno Toxicosis feline methylene blue |
title_short |
Poisoning by methylene blue (methylthioninium chloride) in cat |
title_full |
Poisoning by methylene blue (methylthioninium chloride) in cat |
title_fullStr |
Poisoning by methylene blue (methylthioninium chloride) in cat |
title_full_unstemmed |
Poisoning by methylene blue (methylthioninium chloride) in cat |
title_sort |
Poisoning by methylene blue (methylthioninium chloride) in cat |
author |
Costa, Samay Zillmann Rocha |
author_facet |
Costa, Samay Zillmann Rocha Cid, Gabriela de Carvalho D’Avila, Mariana Sequeira França, Ticiana Nascimento dos Santos, Bartolomeu Benedito Neves Nogueira, Vivian de Assunção dos Santos, André Marandola Peixoto, Tiago da Cunha |
author_role |
author |
author2 |
Cid, Gabriela de Carvalho D’Avila, Mariana Sequeira França, Ticiana Nascimento dos Santos, Bartolomeu Benedito Neves Nogueira, Vivian de Assunção dos Santos, André Marandola Peixoto, Tiago da Cunha |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Costa, Samay Zillmann Rocha Cid, Gabriela de Carvalho D’Avila, Mariana Sequeira França, Ticiana Nascimento dos Santos, Bartolomeu Benedito Neves Nogueira, Vivian de Assunção dos Santos, André Marandola Peixoto, Tiago da Cunha |
dc.subject.por.fl_str_mv |
Toxicose felino azul de metileno Toxicosis feline methylene blue |
topic |
Toxicose felino azul de metileno Toxicosis feline methylene blue |
description |
ABSTRACT. Costa S.Z.R., Cid G.C., D’Avila M.S., França T.N., Santos B.B.N., Nogueira V.A., Santos A.M. & Peixoto T.C. [Poisoning by methylene blue (methylthioninium chloride) in cat.] Intoxicação por azul de metileno (cloreto de metiltionínio) em gato. Revista Brasileira de Medicina Veterinária, 38(Supl.2):143- 146, 2016. Departamento de Epidemiologia e Saúde Pública, Universidade Federal Rural do Rio de Janeiro, Campus de Seropédica, Rodovia BR 465 Km 7, Seropédica, RJ 23851-970, Brasil. E-mail: vivianmedvet@yahoo.com.br It’s reported a case of poisoning by methylene blue (methylthioniniumchloride) in cat that was sent to the Pathological Anatomy Sector of UFRRJ in October 2011, with history of urinary tract infection. By means of necropsy, mucous, subcutaneous tissue, medullary region of the kidney, serous bladder and adjacent tissues to the bladder with clear bluish tint, disclosure of hepatic lobular pattern, additionally bladder mucosa bluishand urine with sediments, blackened and foul odor were observed. Histopathological analysis showed micro and macrovesicular vacuolation of hepatocytes, overall in centrilobular region, which could extend to midzonal lobule region; some cells were lysed. There was, additionally, individual necrosis of rare hepatocytes and biliary retention, increase of the filtrate in tubules and glomeruli, with dilation of Bowman’s capsule, vacuolized tubular epithelium and thickening of the glomerular basement membrane. There was coagulation necrosis in some tubules of the medular area and small quantity of yellow-brown pigment in the cytoplasm of the tubular epithelium. The diagnosis of poisoning by methylene blue (methylthioninium chloride) was established based on the animal’s history and the clinical and pathological findings. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer reviewed Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/196 |
url |
https://rbmv.org/BJVM/article/view/196 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/196/126 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl.2 (2016); 145-148 Revista Brasileira de Medicina Veterinária; v. 38 n. Supl.2 (2016); 145-148 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
instname_str |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
instacron_str |
SBMV |
institution |
SBMV |
reponame_str |
Brazilian Journal of Veterinary Medicine |
collection |
Brazilian Journal of Veterinary Medicine |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
repository.mail.fl_str_mv |
contato.rbmv@gmail.com |
_version_ |
1798313106919653376 |