Clinical-loboratory evaluation of monensin employment in prevention of lactic ruminal acidosis in goats

• Autor(a) principal: da Silva, Saulo de Tarso Gusmão
• Data de Publicação: 2013
• Outros Autores: Neto, Eldinê Gomes de Miranda, de Mendonça, Carla Lopes, Carvalho, Cleyton Charles Dantas, Afonso, José Augusto Bastos
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Veterinary Medicine
• Texto Completo: https://rbmv.org/BJVM/article/view/578
• topic: Ionóforo; Distúrbio digestivo; Pequenos ruminantes; bioquímica clínica; Ionophore; digestive disorders; small ruminants; biochemistry

ABSTRACT. Silva S.T.G., Miranda Neto E.G., de Mendonça C.L., Carvalho C.C.D. &Afonso J.A.B. [Clinical-loboratory evaluation of monensin employment in prevention of lactic ruminal acidosis in goats]. Avaliação clinico-laboratorial do emprego da monensina sódica na prevenção da acidose láctica ruminal em caprinos. Revista Brasileira de Medicina Veterinária, 35(1):76-84. 2013. Clínica de Bovinos, Campus Garanhuns, Universidade Federal Rural de Pernambuco, Cx. Postal 152, Garanhuns, PE 55292-901, Brazil. E-mail: [e-mail] The increase in technification and search for higher yields, increases the chances of errors in management, favoring the occurrence of disturbances such as acidosis lactic fermentation in the rumen. The objective of this study was to evaluate the use of monensin in the prevention of ruminal lactic acidosis induced in goats by the observation of clinical manifestations and hematological and biochemical parameters. They were induced acidosis by intra-ruminal administration of sucrose at a dose of 10 g / kg body weight at eight o’clock in the morning, before feeding rumen. The animals showed clinical signs such as apathy, appetite capricious, and bloat from 4h IP. There was a change in color of the ruminal fluid, becoming milky, but a significant decrease in rumen pH (p <0.05) to below six at 4 PI in both groups tested. There was a hemoconcentration in the early stages, leukocytosis with neutrophilia and inversion of neutrophils: linfóvitos occurred at 4 PI in both groups, returning to normal at 72h PI. The values of plasma fibrinogen, serum ALP activity, AST and creatinine remained within normal values. The activity of CK, GGT, values of urea, glucose and cortisol elevated Were, But without Statistical significance (p> 0.05) Between groups. The monensin Offered daily for 40 days at a dose of 33mg/animal, did not Prevent the onset of rumen acidosis in goats lactis study and did not cause marked changes in hematologic and biochemical profile of these animals.