Detomidine and xylazine, at different doses, in donkeys (Equus asinus)

Detalhes bibliográficos
Autor(a) principal: Parentoni, Roberta Nunes
Data de Publicação: 2021
Outros Autores: Henrique, Fernanda Vieira, Brasil, Arthur Willian de Lima, Dias, Rafaela Alves, Araújo, Ana Lucélia de Araújo, Mendes, Rodrigo de Souza, Martins Filho, Emanuel Ferreira, Costa Neto, João Moreira da, de Souza, Almir Pereira, da Nóbrega Neto, Pedro Isidro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Veterinary Medicine
Texto Completo: https://rbmv.org/BJVM/article/view/1008
Resumo: The effects of detomidine and xylazine in northeasters donkeys were compared. Six animals participated, randomly, of all experimental groups: xylazine 10%, 0.8 mg/kg (xylazine group 0.8 - GX0.8), 1.0 mg/kg (GX1.0) and 1, 2 mg/kg (GX1.2); and detomidine 1%, 0.02 mg/kg (Detomidine group 0.02 - GD0.02), 0.04 mg/kg (GD0.04) and 0.06 mg/kg (GD0.06) intravenous. Heart rate (HR) and respiratory rate (RR), rectal temperature (RT), mean arterial pressure (MAP), blood glucose, sedation, analgesia, ataxia, arrhythmias and urination were monitored. Duration of sedation was greater in the groups in which detomidine was administered. The muzzle-soil distance significantly reduced in all groups five minutes after the sedative administration, remaining smaller for a longer time in the GD0.06. Ataxia in GX1.0 was greater than in GX0.08 and GX1,2, being equivalent to GD0,04 and GD0,06. Analgesia lasted 30 minutes in GD0.06 and 10 minutes in the others. There was reduction of HR in GD0.02 and GD0.04 and atrioventricular block. There was a reduction in TR in GX1,2, GD0.02, GD0,04 and GD0,06. RR decreased in all groups. MAP increased in GD0.02, GD0.04 and GD0.06 five, 20, 30 and 10 minutes after administration of detomidine, respectively. Hyperglycaemia occurred for 120 minutes in all animals receiving detomidine. The frequency of micturition was higher in GD0.06 (2.2 ± 0.8) than in GX0.8 (0.8 ± 0.4). In northern Brazil, detomidine and xylazine promote short duration analgesia and cardiorespiratory alterations, but detomidine causes a greater sedative, hypertensive and hypothermic effect.
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spelling Detomidine and xylazine, at different doses, in donkeys (Equus asinus)Detomidina e xilazina, em diferentes doses, em asininos (Equus asinus)agonista alfa-2 adrenérgicoanalgesiaequídeossedaçãoalpha-2 adrenergic agonistanalgesiaequinesedationThe effects of detomidine and xylazine in northeasters donkeys were compared. Six animals participated, randomly, of all experimental groups: xylazine 10%, 0.8 mg/kg (xylazine group 0.8 - GX0.8), 1.0 mg/kg (GX1.0) and 1, 2 mg/kg (GX1.2); and detomidine 1%, 0.02 mg/kg (Detomidine group 0.02 - GD0.02), 0.04 mg/kg (GD0.04) and 0.06 mg/kg (GD0.06) intravenous. Heart rate (HR) and respiratory rate (RR), rectal temperature (RT), mean arterial pressure (MAP), blood glucose, sedation, analgesia, ataxia, arrhythmias and urination were monitored. Duration of sedation was greater in the groups in which detomidine was administered. The muzzle-soil distance significantly reduced in all groups five minutes after the sedative administration, remaining smaller for a longer time in the GD0.06. Ataxia in GX1.0 was greater than in GX0.08 and GX1,2, being equivalent to GD0,04 and GD0,06. Analgesia lasted 30 minutes in GD0.06 and 10 minutes in the others. There was reduction of HR in GD0.02 and GD0.04 and atrioventricular block. There was a reduction in TR in GX1,2, GD0.02, GD0,04 and GD0,06. RR decreased in all groups. MAP increased in GD0.02, GD0.04 and GD0.06 five, 20, 30 and 10 minutes after administration of detomidine, respectively. Hyperglycaemia occurred for 120 minutes in all animals receiving detomidine. The frequency of micturition was higher in GD0.06 (2.2 ± 0.8) than in GX0.8 (0.8 ± 0.4). In northern Brazil, detomidine and xylazine promote short duration analgesia and cardiorespiratory alterations, but detomidine causes a greater sedative, hypertensive and hypothermic effect.Compararam-se os efeitos da detomidina e da xilazina em asininos. Foram utilizados, aleatoriamente, seis animais, os quais participaram de seis grupos experimentais: xilazina 10%, 0,8 mg/kg (Grupo xilazina 0,8 - GX0,8), 1,0 mg/kg (GX1,0) e 1,2 mg/kg (GX1,2); e detomidina 1%, 20 µg/kg (Grupo detomidina 20 – GD20), 40 µg/kg (GD40) e 60 µg/kg (GD60), administrados por via intravenosa. Foram monitorados: frequências cardíaca (FC) e respiratória (FR), temperatura retal (TR), pressão arterial média (PAM), glicemia, sedação, analgesia, ataxia, arritmias e micção. Duração da sedação foi maior nos grupos nos quais foi administrada detomidina, durando, em média, 140 minutos no GD60 e 47 minutos no GX1,2. Analgesia durou 30 minutos no GD60 e apenas 10 minutos nos demais grupos em que se utilizou a detomidina e nos grupos da xilazina. Ocorreu redução da FC no GD20 e no GD40 e bloqueio atrioventricular. Ocorreu redução na TR em GX1,2, GD20, GD40 e GD60. A FR diminuiu em todos os grupos. A PAM aumentou no GD20, GD40 e GD60 cinco, 20, 30 e 10 minutos após a administração da detomidina, respectivamente. Ocorreu hiperglicemia por 120 minutos em todos os animais que receberam detomidina. A frequência de micções foi maior no GD60 (2,2 ± 0,8) que no GX0,8 (0,8 ± 0,4). Em asininos, a detomidina e a xilazina promovem analgesia de curta duração e discretas alterações cardiorrespiratórias, havendo segurança e eficácia com as doses utilizadas.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2021-05-13info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfhttps://rbmv.org/BJVM/article/view/100810.29374/2527-2179.bjvm100820Brazilian Journal of Veterinary Medicine; Vol. 42 No. 1 (2020); e100820Revista Brasileira de Medicina Veterinária; v. 42 n. 1 (2020); e1008202527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVenghttps://rbmv.org/BJVM/article/view/1008/980Copyright (c) 2020 Fernanda Vieira Henrique, Roberta Nunes Parentoni, Arthur Willian de Lima Brasil, Rafaela Alves Dias, Ana Lucélia de Araújo Araújo, Rodrigo de Souza Mendes, Emanuel Ferreira Martins Filho, João Moreira da Costa Neto, Almir Pereira de Souza, Pedro Isidro da Nóbrega Netohttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessParentoni, Roberta NunesHenrique, Fernanda VieiraBrasil, Arthur Willian de LimaDias, Rafaela AlvesAraújo, Ana Lucélia de AraújoMendes, Rodrigo de SouzaMartins Filho, Emanuel FerreiraCosta Neto, João Moreira dade Souza, Almir Pereirada Nóbrega Neto, Pedro Isidro2021-05-13T13:46:40Zoai:ojs.rbmv.org:article/1008Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2021-05-13T13:46:40Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false
dc.title.none.fl_str_mv Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
Detomidina e xilazina, em diferentes doses, em asininos (Equus asinus)
title Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
spellingShingle Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
Parentoni, Roberta Nunes
agonista alfa-2 adrenérgico
analgesia
equídeos
sedação
alpha-2 adrenergic agonist
analgesia
equine
sedation
title_short Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
title_full Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
title_fullStr Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
title_full_unstemmed Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
title_sort Detomidine and xylazine, at different doses, in donkeys (Equus asinus)
author Parentoni, Roberta Nunes
author_facet Parentoni, Roberta Nunes
Henrique, Fernanda Vieira
Brasil, Arthur Willian de Lima
Dias, Rafaela Alves
Araújo, Ana Lucélia de Araújo
Mendes, Rodrigo de Souza
Martins Filho, Emanuel Ferreira
Costa Neto, João Moreira da
de Souza, Almir Pereira
da Nóbrega Neto, Pedro Isidro
author_role author
author2 Henrique, Fernanda Vieira
Brasil, Arthur Willian de Lima
Dias, Rafaela Alves
Araújo, Ana Lucélia de Araújo
Mendes, Rodrigo de Souza
Martins Filho, Emanuel Ferreira
Costa Neto, João Moreira da
de Souza, Almir Pereira
da Nóbrega Neto, Pedro Isidro
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Parentoni, Roberta Nunes
Henrique, Fernanda Vieira
Brasil, Arthur Willian de Lima
Dias, Rafaela Alves
Araújo, Ana Lucélia de Araújo
Mendes, Rodrigo de Souza
Martins Filho, Emanuel Ferreira
Costa Neto, João Moreira da
de Souza, Almir Pereira
da Nóbrega Neto, Pedro Isidro
dc.subject.por.fl_str_mv agonista alfa-2 adrenérgico
analgesia
equídeos
sedação
alpha-2 adrenergic agonist
analgesia
equine
sedation
topic agonista alfa-2 adrenérgico
analgesia
equídeos
sedação
alpha-2 adrenergic agonist
analgesia
equine
sedation
description The effects of detomidine and xylazine in northeasters donkeys were compared. Six animals participated, randomly, of all experimental groups: xylazine 10%, 0.8 mg/kg (xylazine group 0.8 - GX0.8), 1.0 mg/kg (GX1.0) and 1, 2 mg/kg (GX1.2); and detomidine 1%, 0.02 mg/kg (Detomidine group 0.02 - GD0.02), 0.04 mg/kg (GD0.04) and 0.06 mg/kg (GD0.06) intravenous. Heart rate (HR) and respiratory rate (RR), rectal temperature (RT), mean arterial pressure (MAP), blood glucose, sedation, analgesia, ataxia, arrhythmias and urination were monitored. Duration of sedation was greater in the groups in which detomidine was administered. The muzzle-soil distance significantly reduced in all groups five minutes after the sedative administration, remaining smaller for a longer time in the GD0.06. Ataxia in GX1.0 was greater than in GX0.08 and GX1,2, being equivalent to GD0,04 and GD0,06. Analgesia lasted 30 minutes in GD0.06 and 10 minutes in the others. There was reduction of HR in GD0.02 and GD0.04 and atrioventricular block. There was a reduction in TR in GX1,2, GD0.02, GD0,04 and GD0,06. RR decreased in all groups. MAP increased in GD0.02, GD0.04 and GD0.06 five, 20, 30 and 10 minutes after administration of detomidine, respectively. Hyperglycaemia occurred for 120 minutes in all animals receiving detomidine. The frequency of micturition was higher in GD0.06 (2.2 ± 0.8) than in GX0.8 (0.8 ± 0.4). In northern Brazil, detomidine and xylazine promote short duration analgesia and cardiorespiratory alterations, but detomidine causes a greater sedative, hypertensive and hypothermic effect.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-13
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer reviewed
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbmv.org/BJVM/article/view/1008
10.29374/2527-2179.bjvm100820
url https://rbmv.org/BJVM/article/view/1008
identifier_str_mv 10.29374/2527-2179.bjvm100820
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbmv.org/BJVM/article/view/1008/980
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Medicine; Vol. 42 No. 1 (2020); e100820
Revista Brasileira de Medicina Veterinária; v. 42 n. 1 (2020); e100820
2527-2179
0100-2430
reponame:Brazilian Journal of Veterinary Medicine
instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron:SBMV
instname_str Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron_str SBMV
institution SBMV
reponame_str Brazilian Journal of Veterinary Medicine
collection Brazilian Journal of Veterinary Medicine
repository.name.fl_str_mv Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
repository.mail.fl_str_mv contato.rbmv@gmail.com
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