EFFECT OF VIRGINIAMYCIN ON COLONIC MICROBIOTA OF THE EQUINES IN CARBOIDRATES OVERLOAD

• Autor(a) principal: Maia, Milena Alves
• Data de Publicação: 2010
• Outros Autores: Roier, Érica Cristina Rocha, dos Reis, Tatiana Pessoa, Botteon, Rita de Cássia Campbell Machado, de Souza, Miliane Moreira, Botteon, Paulo de Tarso Landgraf
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Veterinary Medicine
• Texto Completo: https://rbmv.org/BJVM/article/view/858
• topic: Equinos; virginiamicina; população bacteriana; acidose intestinal; Equine; virginiamycin; bacterial community; hindgut acidosis

ABSTRACT. Maia M.A., Roier C.R., Reis T.P., Botteon R.C.C.M., de Souza M.M. & Botteon P.T.L. [Effect of virginiamycin on colonic microbiota of the equines in carboidrates overload]. Efeito da virginiamicina sobre a microbiota colônica de equinos submetidos à sobrecarga experimental por carboidratos. Revista Brasileira de Medicina Veterinária, 32(4):229-233, 2010. Departamento de Medicina e Cirurgia Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, BR-465 km 07, Seropédica, 23890-000, RJ, Brasil. E-mail: [e-mail] The aim of this work was to evaluate the changes of aerobic microbiota in the colon of horses subjected to carbohydrate overload (CO) and to verify the effect of virginiamycin administered at differents times on the colonic microbiota. Were used four colostomized horses in a randomized 4x4 cross over design. The animals were subjected to CO and treated with differents doses of virginiamycin (V), in according to the treatments of V: C (control) = 0 mg, V0=5 mg V at zero hours after CO (ACO); V12 V = 5mg at 12 hours ACO; V0-12 = 5mg of V at zero hours ACO and 5mg of V at 12 hours ACO. The initial microbiota was related Gram positive / Gram-negative bacteria of the order of 53% and 46% respectively. Was isolated the gram-negatives bacteria: Escherichia coli, Klebsiella pneumonae, Serratia rubideae, Shigella sonnei, Enterobacter aerogines, E. agglomerans, E. sakazakii. And the gram-positive bacteria: Bacillus sp., Corynebacterium sp., Pseudomonas sp., Listeria sp., Streptococcus sp., Staphylococcus sp., and Levedures. The administration of virginiamycin simultaneously to CO inhibited the growth of grampositive bacteria, but does not prevent the reduction of pH and death of Gram-negative bacteria. Virginiamycin 12 hours ACO reduced the population of gram-positive and promoted an increase in pH. We conclude that administration of virginiamycin simultaneously with carbohydrate overload or 12 hours lather may be beneficial for control of the population of gram-positive bacteria, producing lactic acid.