Risk factors for the progression of chronic kidney disease after acute kidney injury

Detalhes bibliográficos
Autor(a) principal: Pereira,Benedito Jorge
Data de Publicação: 2017
Outros Autores: Barreto,Silvana, Gentil,Thais, Assis,Larissa S., Soeiro,Emília MD, Castro,Isac de, Laranja,Sandra M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300239
Resumo: Abstract Introduction: The incidence of chronic kidney disease (CKD) is increasing with the increasing age of the population and the increasing number of elderly survivors of acute kidney injury (AKI). The risk factors for the progression of CKD after AKI are unclear. Objective: To investigate the association between AKI and its progression to CKD and the risk factors involved. Methods: An observational, retrospective study of AKI patients followed from 2009 to 2012 was carried out. We evaluated the etiology of AKI, the use of vasoactive drugs and mechanical ventilation, the need for dialysis, the presence of comorbidities, the glomerular filtration rate (GFR), the length of stay and the progression of CKD. Statistical analyses, including the Chi-square test and Pearson's correlation, were performed using SPSS. Results: The 207 patients analyzed had a mean age of 70.1 ± 13.1, and 84.6% of the male patients exhibited decreased renal function and CKD (vs. 60.4% of the female patients). The progression of AKI to CKD was more frequent in patients admitted to wards (63.8%), cancer patients (74.19%), patients with sepsis (67.18%) and patients with obstruction (91.66%). Dialyses were performed in 16.4% of the patients, but this was not correlated with the progression of CKD. Conclusions: Being an elderly male patient with AKI due to sepsis and obstruction was correlated with progression to CKD following discharge.
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spelling Risk factors for the progression of chronic kidney disease after acute kidney injuryacute kidney injurykidney diseaseskidney failure, chronicrenal dialysisdialysisAbstract Introduction: The incidence of chronic kidney disease (CKD) is increasing with the increasing age of the population and the increasing number of elderly survivors of acute kidney injury (AKI). The risk factors for the progression of CKD after AKI are unclear. Objective: To investigate the association between AKI and its progression to CKD and the risk factors involved. Methods: An observational, retrospective study of AKI patients followed from 2009 to 2012 was carried out. We evaluated the etiology of AKI, the use of vasoactive drugs and mechanical ventilation, the need for dialysis, the presence of comorbidities, the glomerular filtration rate (GFR), the length of stay and the progression of CKD. Statistical analyses, including the Chi-square test and Pearson's correlation, were performed using SPSS. Results: The 207 patients analyzed had a mean age of 70.1 ± 13.1, and 84.6% of the male patients exhibited decreased renal function and CKD (vs. 60.4% of the female patients). The progression of AKI to CKD was more frequent in patients admitted to wards (63.8%), cancer patients (74.19%), patients with sepsis (67.18%) and patients with obstruction (91.66%). Dialyses were performed in 16.4% of the patients, but this was not correlated with the progression of CKD. Conclusions: Being an elderly male patient with AKI due to sepsis and obstruction was correlated with progression to CKD following discharge.Sociedade Brasileira de Nefrologia2017-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300239Brazilian Journal of Nephrology v.39 n.3 2017reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.5935/0101-2800.20170041info:eu-repo/semantics/openAccessPereira,Benedito JorgeBarreto,SilvanaGentil,ThaisAssis,Larissa S.Soeiro,Emília MDCastro,Isac deLaranja,Sandra M.eng2017-10-10T00:00:00Zoai:scielo:S0101-28002017000300239Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2017-10-10T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Risk factors for the progression of chronic kidney disease after acute kidney injury
title Risk factors for the progression of chronic kidney disease after acute kidney injury
spellingShingle Risk factors for the progression of chronic kidney disease after acute kidney injury
Pereira,Benedito Jorge
acute kidney injury
kidney diseases
kidney failure, chronic
renal dialysis
dialysis
title_short Risk factors for the progression of chronic kidney disease after acute kidney injury
title_full Risk factors for the progression of chronic kidney disease after acute kidney injury
title_fullStr Risk factors for the progression of chronic kidney disease after acute kidney injury
title_full_unstemmed Risk factors for the progression of chronic kidney disease after acute kidney injury
title_sort Risk factors for the progression of chronic kidney disease after acute kidney injury
author Pereira,Benedito Jorge
author_facet Pereira,Benedito Jorge
Barreto,Silvana
Gentil,Thais
Assis,Larissa S.
Soeiro,Emília MD
Castro,Isac de
Laranja,Sandra M.
author_role author
author2 Barreto,Silvana
Gentil,Thais
Assis,Larissa S.
Soeiro,Emília MD
Castro,Isac de
Laranja,Sandra M.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Benedito Jorge
Barreto,Silvana
Gentil,Thais
Assis,Larissa S.
Soeiro,Emília MD
Castro,Isac de
Laranja,Sandra M.
dc.subject.por.fl_str_mv acute kidney injury
kidney diseases
kidney failure, chronic
renal dialysis
dialysis
topic acute kidney injury
kidney diseases
kidney failure, chronic
renal dialysis
dialysis
description Abstract Introduction: The incidence of chronic kidney disease (CKD) is increasing with the increasing age of the population and the increasing number of elderly survivors of acute kidney injury (AKI). The risk factors for the progression of CKD after AKI are unclear. Objective: To investigate the association between AKI and its progression to CKD and the risk factors involved. Methods: An observational, retrospective study of AKI patients followed from 2009 to 2012 was carried out. We evaluated the etiology of AKI, the use of vasoactive drugs and mechanical ventilation, the need for dialysis, the presence of comorbidities, the glomerular filtration rate (GFR), the length of stay and the progression of CKD. Statistical analyses, including the Chi-square test and Pearson's correlation, were performed using SPSS. Results: The 207 patients analyzed had a mean age of 70.1 ± 13.1, and 84.6% of the male patients exhibited decreased renal function and CKD (vs. 60.4% of the female patients). The progression of AKI to CKD was more frequent in patients admitted to wards (63.8%), cancer patients (74.19%), patients with sepsis (67.18%) and patients with obstruction (91.66%). Dialyses were performed in 16.4% of the patients, but this was not correlated with the progression of CKD. Conclusions: Being an elderly male patient with AKI due to sepsis and obstruction was correlated with progression to CKD following discharge.
publishDate 2017
dc.date.none.fl_str_mv 2017-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300239
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300239
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0101-2800.20170041
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.39 n.3 2017
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
instname_str Sociedade Brasileira de Nefrologia (SBN)
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reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
repository.name.fl_str_mv Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)
repository.mail.fl_str_mv ||jbn@sbn.org.br
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