Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Nefrologia |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337 |
Resumo: | Abstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome. |
id |
SBN-1_7f9871914fad815872775799ed2f8d69 |
---|---|
oai_identifier_str |
oai:scielo:S0101-28002017000300337 |
network_acronym_str |
SBN-1 |
network_name_str |
Jornal Brasileiro de Nefrologia |
repository_id_str |
|
spelling |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosishypokalemiaGitelman syndromehyperthyroidismhypokalemic periodic paralysisAbstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome.Sociedade Brasileira de Nefrologia2017-09-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337Brazilian Journal of Nephrology v.39 n.3 2017reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.5935/0101-2800.20170058info:eu-repo/semantics/openAccessMolin,Christine Zomer DalTrevisol,Daisson Joséeng2017-10-10T00:00:00Zoai:scielo:S0101-28002017000300337Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2017-10-10T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false |
dc.title.none.fl_str_mv |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
title |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
spellingShingle |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis Molin,Christine Zomer Dal hypokalemia Gitelman syndrome hyperthyroidism hypokalemic periodic paralysis |
title_short |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
title_full |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
title_fullStr |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
title_full_unstemmed |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
title_sort |
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis |
author |
Molin,Christine Zomer Dal |
author_facet |
Molin,Christine Zomer Dal Trevisol,Daisson José |
author_role |
author |
author2 |
Trevisol,Daisson José |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Molin,Christine Zomer Dal Trevisol,Daisson José |
dc.subject.por.fl_str_mv |
hypokalemia Gitelman syndrome hyperthyroidism hypokalemic periodic paralysis |
topic |
hypokalemia Gitelman syndrome hyperthyroidism hypokalemic periodic paralysis |
description |
Abstract The main causes of hypokalemia are usually evident in the clinical history of patients, with previous episodes of vomiting, diarrhea or diuretic use. However, in some patients the cause of hypokalemia can become a challenge. In such cases, two major components of the investigation must be performed: assessment of urinary excretion potassium and the acid-base status. This article presents a case report of a patient with severe persistent hypokalemia, complementary laboratory tests indicated that's it was hypomagnesaemia and hypocalciuria associated with metabolic alkalosis, and increase of thyroid hormones. Thyrotoxic periodic paralysis was included in the differential diagnosis, but evolved into euthyroid state, persisting with severe hypokalemia, which led to be diagnosed as Gitelman syndrome. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300337 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/0101-2800.20170058 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Nephrology v.39 n.3 2017 reponame:Jornal Brasileiro de Nefrologia instname:Sociedade Brasileira de Nefrologia (SBN) instacron:SBN |
instname_str |
Sociedade Brasileira de Nefrologia (SBN) |
instacron_str |
SBN |
institution |
SBN |
reponame_str |
Jornal Brasileiro de Nefrologia |
collection |
Jornal Brasileiro de Nefrologia |
repository.name.fl_str_mv |
Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN) |
repository.mail.fl_str_mv |
||jbn@sbn.org.br |
_version_ |
1752122064304603136 |