Metabolic acidosis in hemodialysis patients: a review

Detalhes bibliográficos
Autor(a) principal: Rezende,Luiza Raksa
Data de Publicação: 2017
Outros Autores: Souza,Pablo Brandão de, Pereira,Giselly Rosa Modesto, Lugon,Jocemir Ronaldo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300305
Resumo: Abstract Metabolic acidosis is highly prevalent in hemodialysis patients. The disorder is associated with increased mortality and its deleterious effects are already present in the predialysis phase of chronic kidney disease. Metabolic acidosis has been linked to progression of chronic kidney disease, changes in protein and glucose metabolism, bone and muscle disorders and cardiovascular disease. At present, the control of metabolic acidosis in hemodialysis is mainly focused on the supply of bicarbonate during dialysis session, but further studies are needed to set the optimum target serum bicarbonate and the best concentration of the bicarbonate dialysate. The present study reviews pathophysiological and epidemiological aspects of metabolic acidosis in hemodialysis patients and also addresses its adverse effects and treatment.
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spelling Metabolic acidosis in hemodialysis patients: a reviewacidosisrenal dialysisbicarbonatesAbstract Metabolic acidosis is highly prevalent in hemodialysis patients. The disorder is associated with increased mortality and its deleterious effects are already present in the predialysis phase of chronic kidney disease. Metabolic acidosis has been linked to progression of chronic kidney disease, changes in protein and glucose metabolism, bone and muscle disorders and cardiovascular disease. At present, the control of metabolic acidosis in hemodialysis is mainly focused on the supply of bicarbonate during dialysis session, but further studies are needed to set the optimum target serum bicarbonate and the best concentration of the bicarbonate dialysate. The present study reviews pathophysiological and epidemiological aspects of metabolic acidosis in hemodialysis patients and also addresses its adverse effects and treatment.Sociedade Brasileira de Nefrologia2017-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300305Brazilian Journal of Nephrology v.39 n.3 2017reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.5935/0101-2800.20170053info:eu-repo/semantics/openAccessRezende,Luiza RaksaSouza,Pablo Brandão dePereira,Giselly Rosa ModestoLugon,Jocemir Ronaldoeng2017-10-10T00:00:00Zoai:scielo:S0101-28002017000300305Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2017-10-10T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Metabolic acidosis in hemodialysis patients: a review
title Metabolic acidosis in hemodialysis patients: a review
spellingShingle Metabolic acidosis in hemodialysis patients: a review
Rezende,Luiza Raksa
acidosis
renal dialysis
bicarbonates
title_short Metabolic acidosis in hemodialysis patients: a review
title_full Metabolic acidosis in hemodialysis patients: a review
title_fullStr Metabolic acidosis in hemodialysis patients: a review
title_full_unstemmed Metabolic acidosis in hemodialysis patients: a review
title_sort Metabolic acidosis in hemodialysis patients: a review
author Rezende,Luiza Raksa
author_facet Rezende,Luiza Raksa
Souza,Pablo Brandão de
Pereira,Giselly Rosa Modesto
Lugon,Jocemir Ronaldo
author_role author
author2 Souza,Pablo Brandão de
Pereira,Giselly Rosa Modesto
Lugon,Jocemir Ronaldo
author2_role author
author
author
dc.contributor.author.fl_str_mv Rezende,Luiza Raksa
Souza,Pablo Brandão de
Pereira,Giselly Rosa Modesto
Lugon,Jocemir Ronaldo
dc.subject.por.fl_str_mv acidosis
renal dialysis
bicarbonates
topic acidosis
renal dialysis
bicarbonates
description Abstract Metabolic acidosis is highly prevalent in hemodialysis patients. The disorder is associated with increased mortality and its deleterious effects are already present in the predialysis phase of chronic kidney disease. Metabolic acidosis has been linked to progression of chronic kidney disease, changes in protein and glucose metabolism, bone and muscle disorders and cardiovascular disease. At present, the control of metabolic acidosis in hemodialysis is mainly focused on the supply of bicarbonate during dialysis session, but further studies are needed to set the optimum target serum bicarbonate and the best concentration of the bicarbonate dialysate. The present study reviews pathophysiological and epidemiological aspects of metabolic acidosis in hemodialysis patients and also addresses its adverse effects and treatment.
publishDate 2017
dc.date.none.fl_str_mv 2017-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300305
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002017000300305
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0101-2800.20170053
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.39 n.3 2017
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
instname_str Sociedade Brasileira de Nefrologia (SBN)
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institution SBN
reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
repository.name.fl_str_mv Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)
repository.mail.fl_str_mv ||jbn@sbn.org.br
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