Total remission of Tolosa-Hunt Syndrome with single-dose of infliximab

• Autor(a) principal: Gondim,Luís Armando Vitorino Alves de Souza
• Data de Publicação: 2020
• Outros Autores: Guimarães Junior,Luís Armando Gondim, Lima Júnior,Edmundo França, Lima,Filipe Moreira, Mendonça,Marcelo Bezerra de Melo
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista Brasileira de Oftalmologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802020000100059
• topic: Tolosa-Hunt Syndrome; Ophthalmoplegia; Infliximab; Pain

Abstract Tolosa-Hunt syndrome is a painful ophthalmoplegia caused by non-specific granulomatous inflammation, corticoid-sensitive, of the cavernous sinus. The etiology is unknown. Recurrences are common. The diagnosis is made by exclusion, and a variety of other diseases involving the orbital apex, superior orbital fissure and cavernous sinus should be ruled out. This study reports a case of a 29-year-old woman, diagnosed with Tolosa-Hunt Syndrome, who presented ophthalmoparesis and orbital pain. She had poor response to corticotherapy and developed colateral effects, so she was treated with single infliximab dose immunosuppression, evolving total remission of the disease.