Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats

• Autor(a) principal: Barros Filho,Tarcísio Eloy Pessoa
• Data de Publicação: 2003
• Outros Autores: Oliveira,Cláudia Regina G. C. M., Oliveira,Reginaldo Perilo de, Barros,Erika Meirelles Kalil Pessoa de, Marcon,Raphael Martus, Cristante,Alexandre Fogaça
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Acta Ortopédica Brasileira (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-78522003000200007
• topic: Laminectomy; Fibrosis; Wistar rats; expanded inert Polytetrafluoroethylene membrane

Post laminectomy fibrosis in spine surgery has been responsible for a high rate of failure in a short or long term. Many of this patients develop chronic or recurrent pain after surgery of discal herniation, canal stenosis etc. Although there some doubts about the etiology of this problem, it was known that fibrosis interfere with the normal mobility of roots and spinal cord. This factor is considered as the most important aspect in the genesis of the surgical failures. To avoid postoperative fibrosis, a lot of materials of interposition between posterior spine muscles and dura mater were studied, without good response. This paper studied comparatively post laminectomy fibrosis in Wistar rats with the addition of the following materials to avoid it: control group (without interposition) and expanded inert polytetrafluoroethylene membrane (Preclude Spinal Membrane®). It was observed that accurate surgical technique apparently is an important factor to prevent the formation of abundant scar tissue and that the expanded inert polytetrafluoroethylene membrane is an inert material.