Influence of corticoids on healing of the rotator cuff of rats – biomechanical study

Detalhes bibliográficos
Autor(a) principal: Dau,Leonardo
Data de Publicação: 2014
Outros Autores: Abagge,Marcelo, Fruehling,Vagner Messias, Sola Junior,Wilson, Lavrador,José Marcos, Cunha,Luiz Antônio Munhoz da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Ortopedia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400379
Resumo: Objective:To compare healing strength of the infraspinatus tendon of rats with corticoid inoculation, regarding maximum tension, maximum force and rupture force, after injury and experimental repair.Methods:A total of 60 Wistar rats were subjected to tenotomy of the infraspinatus tendon, which was then sutured. Before the surgery, they were divided into a control group (C) inoculated with serum and a study group (S) inoculated with corticoids over the tendon. After repair, the rats were sacrificed in groups of 10 individuals in the control group and 10 in the study group at the times of one week (C1 and S1), three weeks (C3 and S3) and five weeks (C5 and S5). The rats were dissected, separating out the infraspinatus tendon with the humerus. The study specimens were subjected to a traction test, with evaluation of the maximum tension (kgf/cm2), maximum force (kgf) and rupture force (kgf), comparing the study group with the respective control groups.Results:Among the rats sacrificed one week after the procedure, we observed greater maximum tension in group C1 than in group S1. The variables of maximum force (kgf) and rupture force did not differ statistically between the groups investigated. In the same way, among the rats sacrificed three weeks after the procedure, group C3 only showed greater maximum tension than group S3 (p = 0.007), and the other variables did not present differences. Among the rats sacrificed five weeks after the procedure (C5 and S5), none of the parameters studied presented statistical differences.Conclusion:We concluded that corticoid diminished the resistance to maximum tension in the groups sacrificed one and three weeks after the procedure, in comparison with the respective control groups. The other parameters did not show differences between the study and control groups.
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spelling Influence of corticoids on healing of the rotator cuff of rats – biomechanical studyRotator cuffCorticoidsBiomechanicsTendonsObjective:To compare healing strength of the infraspinatus tendon of rats with corticoid inoculation, regarding maximum tension, maximum force and rupture force, after injury and experimental repair.Methods:A total of 60 Wistar rats were subjected to tenotomy of the infraspinatus tendon, which was then sutured. Before the surgery, they were divided into a control group (C) inoculated with serum and a study group (S) inoculated with corticoids over the tendon. After repair, the rats were sacrificed in groups of 10 individuals in the control group and 10 in the study group at the times of one week (C1 and S1), three weeks (C3 and S3) and five weeks (C5 and S5). The rats were dissected, separating out the infraspinatus tendon with the humerus. The study specimens were subjected to a traction test, with evaluation of the maximum tension (kgf/cm2), maximum force (kgf) and rupture force (kgf), comparing the study group with the respective control groups.Results:Among the rats sacrificed one week after the procedure, we observed greater maximum tension in group C1 than in group S1. The variables of maximum force (kgf) and rupture force did not differ statistically between the groups investigated. In the same way, among the rats sacrificed three weeks after the procedure, group C3 only showed greater maximum tension than group S3 (p = 0.007), and the other variables did not present differences. Among the rats sacrificed five weeks after the procedure (C5 and S5), none of the parameters studied presented statistical differences.Conclusion:We concluded that corticoid diminished the resistance to maximum tension in the groups sacrificed one and three weeks after the procedure, in comparison with the respective control groups. The other parameters did not show differences between the study and control groups.Sociedade Brasileira de Ortopedia e Traumatologia2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400379Revista Brasileira de Ortopedia v.49 n.4 2014reponame:Revista Brasileira de Ortopedia (Online)instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)instacron:SBOT10.1016/j.rboe.2014.04.023info:eu-repo/semantics/openAccessDau,LeonardoAbagge,MarceloFruehling,Vagner MessiasSola Junior,WilsonLavrador,José MarcosCunha,Luiz Antônio Munhoz daeng2015-09-23T00:00:00Zoai:scielo:S0102-36162014000400379Revistahttp://www.rbo.org.br/https://old.scielo.br/oai/scielo-oai.php||rbo@sbot.org.br1982-43780102-3616opendoar:2015-09-23T00:00Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)false
dc.title.none.fl_str_mv Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
title Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
spellingShingle Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
Dau,Leonardo
Rotator cuff
Corticoids
Biomechanics
Tendons
title_short Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
title_full Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
title_fullStr Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
title_full_unstemmed Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
title_sort Influence of corticoids on healing of the rotator cuff of rats – biomechanical study
author Dau,Leonardo
author_facet Dau,Leonardo
Abagge,Marcelo
Fruehling,Vagner Messias
Sola Junior,Wilson
Lavrador,José Marcos
Cunha,Luiz Antônio Munhoz da
author_role author
author2 Abagge,Marcelo
Fruehling,Vagner Messias
Sola Junior,Wilson
Lavrador,José Marcos
Cunha,Luiz Antônio Munhoz da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Dau,Leonardo
Abagge,Marcelo
Fruehling,Vagner Messias
Sola Junior,Wilson
Lavrador,José Marcos
Cunha,Luiz Antônio Munhoz da
dc.subject.por.fl_str_mv Rotator cuff
Corticoids
Biomechanics
Tendons
topic Rotator cuff
Corticoids
Biomechanics
Tendons
description Objective:To compare healing strength of the infraspinatus tendon of rats with corticoid inoculation, regarding maximum tension, maximum force and rupture force, after injury and experimental repair.Methods:A total of 60 Wistar rats were subjected to tenotomy of the infraspinatus tendon, which was then sutured. Before the surgery, they were divided into a control group (C) inoculated with serum and a study group (S) inoculated with corticoids over the tendon. After repair, the rats were sacrificed in groups of 10 individuals in the control group and 10 in the study group at the times of one week (C1 and S1), three weeks (C3 and S3) and five weeks (C5 and S5). The rats were dissected, separating out the infraspinatus tendon with the humerus. The study specimens were subjected to a traction test, with evaluation of the maximum tension (kgf/cm2), maximum force (kgf) and rupture force (kgf), comparing the study group with the respective control groups.Results:Among the rats sacrificed one week after the procedure, we observed greater maximum tension in group C1 than in group S1. The variables of maximum force (kgf) and rupture force did not differ statistically between the groups investigated. In the same way, among the rats sacrificed three weeks after the procedure, group C3 only showed greater maximum tension than group S3 (p = 0.007), and the other variables did not present differences. Among the rats sacrificed five weeks after the procedure (C5 and S5), none of the parameters studied presented statistical differences.Conclusion:We concluded that corticoid diminished the resistance to maximum tension in the groups sacrificed one and three weeks after the procedure, in comparison with the respective control groups. The other parameters did not show differences between the study and control groups.
publishDate 2014
dc.date.none.fl_str_mv 2014-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400379
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400379
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rboe.2014.04.023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
dc.source.none.fl_str_mv Revista Brasileira de Ortopedia v.49 n.4 2014
reponame:Revista Brasileira de Ortopedia (Online)
instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
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instname_str Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron_str SBOT
institution SBOT
reponame_str Revista Brasileira de Ortopedia (Online)
collection Revista Brasileira de Ortopedia (Online)
repository.name.fl_str_mv Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
repository.mail.fl_str_mv ||rbo@sbot.org.br
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