Lymphoplasmacyte-rich meningioma: a case report of a rare neoplasm

• Autor(a) principal: Cambruzzi,Eduardo
• Data de Publicação: 2012
• Outros Autores: Souza,Thaís Amara da Costa de, Silveira,Luciano Carvalho, Moreira,Carlos Fernando dos Santos
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000300012
• topic: Pathology; Immunohistochemistry; Central nervous system; Meningioma; Brain tumors

Lymphoplasmacyte-rich meningioma (LPM) is a rare variant of meningioma, which is characterized by massive inflammatory cell infiltration and rare meningothelial elements. The authors report the clinicopathological features of a LPM located at the right parietal convexity in a patient with generalized tonic-clonic seizures and paresthesia in the left arm. The surgical specimen consisted of a gray nodule measuring 3.5 × 3 × 1.8 cm. At microscopy, a few epithelioid cells associated with numerous lymphocytes/plasma cells were identified. Positive immunoexpression for epithelial membrane antigen (EMA) and progesterone receptor was found in the epithelioid cells, and positive staining for CD3, CD5 and CD20 in the inflammatory cells. Thus, the diagnosis of LPM was established.