Angiosarcoma of small intestine: case report and literature review

• Autor(a) principal: Lopes,Roberto Heleno
• Data de Publicação: 2016
• Outros Autores: Resende,Frederico Augustus M., Fraga,João Baptista P., Oliveira,Alexandre F., Pereira,Matheus S. V., Maciel,Bruno A. R., Lamim,Raul Fernando B.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442016000500345
• topic: angiosarcoma; small intestine; immunohistochemistry

ABSTRACT Introduction: Angiosarcomas are rare pathologies, and their appearance in the small intestine is extremely unusual. Case report: Female patient presenting vomiting, colic, abdominal distension and peritoneal irritation. An exploratory laparotomy and an enterectomy were performed. Histopathology revealed vascular neoplasm; immunohistochemistry, markers CD31, p53 and cell proliferation antigen Ki-67. The patient developed diffuse sarcomatosis and died two months after the onset of symptoms. Conclusion: This case demonstrates the difficulty in early diagnosing this pathology, due to its nonspecific clinical presentation. The disease aggressiveness, its unestablished predisposing factors and the controversy around the adequate treatment engender the poor prognosis.