Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum,
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal de Pediatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572017000100040 |
Resumo: | Abstract: Objective: To evaluate the effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum and its supply to the newborn. Method: This randomized clinical trial enrolled 99 healthy adult pregnant women; of these, 39 were assigned to the control group and 60 to the supplemented group. After an overnight fast, 5 mL of blood and 2 mL of colostrum were collected. After the first sampling (0 h milk), the supplemented group received 400 IU of supplementary vitamin E. Another 2 mL milk aliquot was collected in both groups 24 h after supplementation (24 h milk). The samples were analyzed by high-performance liquid chromatography. The α-tocopherol content provided by colostrum was calculated by considering a daily intake of 396 mL of milk and comparing the resulting value to the recommended daily intake for infants aged 0-6 months (4 mg/day). Results: The initial mean concentration of α-tocopherol in colostrum was 1509.3 ± 793.7 µg/dL in the control group and 1452.9 ± 808.6 µg/dL in the supplemented group. After 24 h, the mean α-tocopherol concentration was 1650.6 ± 968.7 µg/dL in the control group (p > 0.05) and 2346.9 ± 1203.2 µg/dL in the supplemented group (p < 0.001), increasing the vitamin E supply to the newborn to 9.3 mg/day. Initially, 18 women in the supplemented group provided colostrum α-tocopherol contents below 4 mg/day; after supplementation only six continued to provide less than the recommended amount. Conclusion: Maternal vitamin E supplementation increases the supply of the vitamin to the infant by providing more than twice the Recommended Daily Intake. |
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Jornal de Pediatria (Online) |
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Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum,Maternal supplementationVitamin EAlpha-tocopherolNutritional needsNewbornHuman colostrumAbstract: Objective: To evaluate the effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum and its supply to the newborn. Method: This randomized clinical trial enrolled 99 healthy adult pregnant women; of these, 39 were assigned to the control group and 60 to the supplemented group. After an overnight fast, 5 mL of blood and 2 mL of colostrum were collected. After the first sampling (0 h milk), the supplemented group received 400 IU of supplementary vitamin E. Another 2 mL milk aliquot was collected in both groups 24 h after supplementation (24 h milk). The samples were analyzed by high-performance liquid chromatography. The α-tocopherol content provided by colostrum was calculated by considering a daily intake of 396 mL of milk and comparing the resulting value to the recommended daily intake for infants aged 0-6 months (4 mg/day). Results: The initial mean concentration of α-tocopherol in colostrum was 1509.3 ± 793.7 µg/dL in the control group and 1452.9 ± 808.6 µg/dL in the supplemented group. After 24 h, the mean α-tocopherol concentration was 1650.6 ± 968.7 µg/dL in the control group (p > 0.05) and 2346.9 ± 1203.2 µg/dL in the supplemented group (p < 0.001), increasing the vitamin E supply to the newborn to 9.3 mg/day. Initially, 18 women in the supplemented group provided colostrum α-tocopherol contents below 4 mg/day; after supplementation only six continued to provide less than the recommended amount. Conclusion: Maternal vitamin E supplementation increases the supply of the vitamin to the infant by providing more than twice the Recommended Daily Intake.Sociedade Brasileira de Pediatria2017-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572017000100040Jornal de Pediatria v.93 n.1 2017reponame:Jornal de Pediatria (Online)instname:Sociedade Brasileira de Pediatria (SBP)instacron:SBPE10.1016/j.jped.2016.03.007info:eu-repo/semantics/openAccessMelo,Larisse Rayanne Miranda deClemente,Heleni AiresBezerra,Dalila FernandesDantas,Raquel Costa SilvaRamalho,Héryka Myrna MaiaDimenstein,Robertoeng2017-02-24T00:00:00Zoai:scielo:S0021-75572017000100040Revistahttp://www.jped.com.br/https://old.scielo.br/oai/scielo-oai.php||jped@jped.com.br1678-47820021-7557opendoar:2017-02-24T00:00Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)false |
dc.title.none.fl_str_mv |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
title |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
spellingShingle |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, Melo,Larisse Rayanne Miranda de Maternal supplementation Vitamin E Alpha-tocopherol Nutritional needs Newborn Human colostrum |
title_short |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
title_full |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
title_fullStr |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
title_full_unstemmed |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
title_sort |
Effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum, |
author |
Melo,Larisse Rayanne Miranda de |
author_facet |
Melo,Larisse Rayanne Miranda de Clemente,Heleni Aires Bezerra,Dalila Fernandes Dantas,Raquel Costa Silva Ramalho,Héryka Myrna Maia Dimenstein,Roberto |
author_role |
author |
author2 |
Clemente,Heleni Aires Bezerra,Dalila Fernandes Dantas,Raquel Costa Silva Ramalho,Héryka Myrna Maia Dimenstein,Roberto |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Melo,Larisse Rayanne Miranda de Clemente,Heleni Aires Bezerra,Dalila Fernandes Dantas,Raquel Costa Silva Ramalho,Héryka Myrna Maia Dimenstein,Roberto |
dc.subject.por.fl_str_mv |
Maternal supplementation Vitamin E Alpha-tocopherol Nutritional needs Newborn Human colostrum |
topic |
Maternal supplementation Vitamin E Alpha-tocopherol Nutritional needs Newborn Human colostrum |
description |
Abstract: Objective: To evaluate the effect of maternal supplementation with vitamin E on the concentration of α-tocopherol in colostrum and its supply to the newborn. Method: This randomized clinical trial enrolled 99 healthy adult pregnant women; of these, 39 were assigned to the control group and 60 to the supplemented group. After an overnight fast, 5 mL of blood and 2 mL of colostrum were collected. After the first sampling (0 h milk), the supplemented group received 400 IU of supplementary vitamin E. Another 2 mL milk aliquot was collected in both groups 24 h after supplementation (24 h milk). The samples were analyzed by high-performance liquid chromatography. The α-tocopherol content provided by colostrum was calculated by considering a daily intake of 396 mL of milk and comparing the resulting value to the recommended daily intake for infants aged 0-6 months (4 mg/day). Results: The initial mean concentration of α-tocopherol in colostrum was 1509.3 ± 793.7 µg/dL in the control group and 1452.9 ± 808.6 µg/dL in the supplemented group. After 24 h, the mean α-tocopherol concentration was 1650.6 ± 968.7 µg/dL in the control group (p > 0.05) and 2346.9 ± 1203.2 µg/dL in the supplemented group (p < 0.001), increasing the vitamin E supply to the newborn to 9.3 mg/day. Initially, 18 women in the supplemented group provided colostrum α-tocopherol contents below 4 mg/day; after supplementation only six continued to provide less than the recommended amount. Conclusion: Maternal vitamin E supplementation increases the supply of the vitamin to the infant by providing more than twice the Recommended Daily Intake. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572017000100040 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572017000100040 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jped.2016.03.007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
dc.source.none.fl_str_mv |
Jornal de Pediatria v.93 n.1 2017 reponame:Jornal de Pediatria (Online) instname:Sociedade Brasileira de Pediatria (SBP) instacron:SBPE |
instname_str |
Sociedade Brasileira de Pediatria (SBP) |
instacron_str |
SBPE |
institution |
SBPE |
reponame_str |
Jornal de Pediatria (Online) |
collection |
Jornal de Pediatria (Online) |
repository.name.fl_str_mv |
Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP) |
repository.mail.fl_str_mv |
||jped@jped.com.br |
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1752122320902684672 |