Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal de Pediatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500500 |
Resumo: | Abstract Objective: To assess the protective effect of exclusive breastfeeding and the effectiveness of maternal vaccination in reducing pertussis-like illness. Method: This was a case-control study conducted in sentinel hospitals for pertussis in Recife between July 2016 and July 2018. Cases included children aged under six months with symptoms compatible with pertussis (pertussis-like illness). Controls included children aged under six months, living in the metropolitan region of Recife with no diagnosis of pertussis-like illness and matched by the same hospital and birth date. Results: Seventy-three cases and 194 controls were included. The diagnosis of pertussis-like illness was predominantly clinical (97,2%). Amongst the main symptoms, paroxysmal cough was observed in 95.89% of cases and vomiting in 53.4%. There were 29 hospitalized cases and no deaths. Out of the 73 cases, 47 were born to mothers vaccinated against pertussis during pregnancy, and the mothers of 144 of the 194 controls had been vaccinated. The protective effect of breastfeeding was of 74% (95% CI;38%, 89%). Children younger than six months, who were exclusively breastfed and with mothers vaccinated against pertussis during pregnancy were 5 times less likely to develop pertussis-like illness, corresponding to a protection of 79% (95% CI;31%, 94%). The effectiveness of maternal vaccination against pertussis-like illness in children under six months was low (27%) and not statistically significant (CI 95%; −34% a 60%). Conclusions: Exclusive breastfeeding protects children under six months from pertussis-like illness and may be enhanced when associated with maternal vaccination. These strategies should be encouraged because they also protect against pertussis-like illnesses. |
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Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illnessPertussisBreastfeedingDiphtheriatetanus and acellular pertussis vaccineImmunizationEffectivenessAbstract Objective: To assess the protective effect of exclusive breastfeeding and the effectiveness of maternal vaccination in reducing pertussis-like illness. Method: This was a case-control study conducted in sentinel hospitals for pertussis in Recife between July 2016 and July 2018. Cases included children aged under six months with symptoms compatible with pertussis (pertussis-like illness). Controls included children aged under six months, living in the metropolitan region of Recife with no diagnosis of pertussis-like illness and matched by the same hospital and birth date. Results: Seventy-three cases and 194 controls were included. The diagnosis of pertussis-like illness was predominantly clinical (97,2%). Amongst the main symptoms, paroxysmal cough was observed in 95.89% of cases and vomiting in 53.4%. There were 29 hospitalized cases and no deaths. Out of the 73 cases, 47 were born to mothers vaccinated against pertussis during pregnancy, and the mothers of 144 of the 194 controls had been vaccinated. The protective effect of breastfeeding was of 74% (95% CI;38%, 89%). Children younger than six months, who were exclusively breastfed and with mothers vaccinated against pertussis during pregnancy were 5 times less likely to develop pertussis-like illness, corresponding to a protection of 79% (95% CI;31%, 94%). The effectiveness of maternal vaccination against pertussis-like illness in children under six months was low (27%) and not statistically significant (CI 95%; −34% a 60%). Conclusions: Exclusive breastfeeding protects children under six months from pertussis-like illness and may be enhanced when associated with maternal vaccination. These strategies should be encouraged because they also protect against pertussis-like illnesses.Sociedade Brasileira de Pediatria2021-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500500Jornal de Pediatria v.97 n.5 2021reponame:Jornal de Pediatria (Online)instname:Sociedade Brasileira de Pediatria (SBP)instacron:SBPE10.1016/j.jped.2020.10.018info:eu-repo/semantics/openAccessNascimento,Renata Medeiros doBaptista,Paulo NevesLopes,Katiuscia Araújo de MirandaPimentel,Analíria MoraesCruz,Fábia da Silva PereiraXimenes,Ricardo Arraes de Alencareng2021-10-08T00:00:00Zoai:scielo:S0021-75572021000500500Revistahttp://www.jped.com.br/https://old.scielo.br/oai/scielo-oai.php||jped@jped.com.br1678-47820021-7557opendoar:2021-10-08T00:00Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)false |
dc.title.none.fl_str_mv |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
title |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
spellingShingle |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness Nascimento,Renata Medeiros do Pertussis Breastfeeding Diphtheria tetanus and acellular pertussis vaccine Immunization Effectiveness |
title_short |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
title_full |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
title_fullStr |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
title_full_unstemmed |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
title_sort |
Protective effect of exclusive breastfeeding and effectiveness of maternal vaccination in reducing pertussis-like illness |
author |
Nascimento,Renata Medeiros do |
author_facet |
Nascimento,Renata Medeiros do Baptista,Paulo Neves Lopes,Katiuscia Araújo de Miranda Pimentel,Analíria Moraes Cruz,Fábia da Silva Pereira Ximenes,Ricardo Arraes de Alencar |
author_role |
author |
author2 |
Baptista,Paulo Neves Lopes,Katiuscia Araújo de Miranda Pimentel,Analíria Moraes Cruz,Fábia da Silva Pereira Ximenes,Ricardo Arraes de Alencar |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Nascimento,Renata Medeiros do Baptista,Paulo Neves Lopes,Katiuscia Araújo de Miranda Pimentel,Analíria Moraes Cruz,Fábia da Silva Pereira Ximenes,Ricardo Arraes de Alencar |
dc.subject.por.fl_str_mv |
Pertussis Breastfeeding Diphtheria tetanus and acellular pertussis vaccine Immunization Effectiveness |
topic |
Pertussis Breastfeeding Diphtheria tetanus and acellular pertussis vaccine Immunization Effectiveness |
description |
Abstract Objective: To assess the protective effect of exclusive breastfeeding and the effectiveness of maternal vaccination in reducing pertussis-like illness. Method: This was a case-control study conducted in sentinel hospitals for pertussis in Recife between July 2016 and July 2018. Cases included children aged under six months with symptoms compatible with pertussis (pertussis-like illness). Controls included children aged under six months, living in the metropolitan region of Recife with no diagnosis of pertussis-like illness and matched by the same hospital and birth date. Results: Seventy-three cases and 194 controls were included. The diagnosis of pertussis-like illness was predominantly clinical (97,2%). Amongst the main symptoms, paroxysmal cough was observed in 95.89% of cases and vomiting in 53.4%. There were 29 hospitalized cases and no deaths. Out of the 73 cases, 47 were born to mothers vaccinated against pertussis during pregnancy, and the mothers of 144 of the 194 controls had been vaccinated. The protective effect of breastfeeding was of 74% (95% CI;38%, 89%). Children younger than six months, who were exclusively breastfed and with mothers vaccinated against pertussis during pregnancy were 5 times less likely to develop pertussis-like illness, corresponding to a protection of 79% (95% CI;31%, 94%). The effectiveness of maternal vaccination against pertussis-like illness in children under six months was low (27%) and not statistically significant (CI 95%; −34% a 60%). Conclusions: Exclusive breastfeeding protects children under six months from pertussis-like illness and may be enhanced when associated with maternal vaccination. These strategies should be encouraged because they also protect against pertussis-like illnesses. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500500 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500500 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jped.2020.10.018 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
dc.source.none.fl_str_mv |
Jornal de Pediatria v.97 n.5 2021 reponame:Jornal de Pediatria (Online) instname:Sociedade Brasileira de Pediatria (SBP) instacron:SBPE |
instname_str |
Sociedade Brasileira de Pediatria (SBP) |
instacron_str |
SBPE |
institution |
SBPE |
reponame_str |
Jornal de Pediatria (Online) |
collection |
Jornal de Pediatria (Online) |
repository.name.fl_str_mv |
Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP) |
repository.mail.fl_str_mv |
||jped@jped.com.br |
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1752122322804801536 |