Influence of different durations of estrogen deficiency on alveolar bone loss in rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000600011 |
Resumo: | The purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss. |
id |
SBPQO-1_2a9afa983172cc0cb119d125e77e7c35 |
---|---|
oai_identifier_str |
oai:scielo:S1806-83242011000600011 |
network_acronym_str |
SBPQO-1 |
network_name_str |
Brazilian Oral Research |
repository_id_str |
|
spelling |
Influence of different durations of estrogen deficiency on alveolar bone loss in ratsAlveolar Bone LossPeriodontitisBone DiseasesThe purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2011-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000600011Brazilian Oral Research v.25 n.6 2011reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242011000600011info:eu-repo/semantics/openAccessAmadei,Susana UngaroSouza,Daniela Martins deBrandão,Adriana Aigotti HaberbeckRocha,Rosilene Fernandes daeng2011-12-13T00:00:00Zoai:scielo:S1806-83242011000600011Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2011-12-13T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
spellingShingle |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats Amadei,Susana Ungaro Alveolar Bone Loss Periodontitis Bone Diseases |
title_short |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_full |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_fullStr |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_full_unstemmed |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
title_sort |
Influence of different durations of estrogen deficiency on alveolar bone loss in rats |
author |
Amadei,Susana Ungaro |
author_facet |
Amadei,Susana Ungaro Souza,Daniela Martins de Brandão,Adriana Aigotti Haberbeck Rocha,Rosilene Fernandes da |
author_role |
author |
author2 |
Souza,Daniela Martins de Brandão,Adriana Aigotti Haberbeck Rocha,Rosilene Fernandes da |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Amadei,Susana Ungaro Souza,Daniela Martins de Brandão,Adriana Aigotti Haberbeck Rocha,Rosilene Fernandes da |
dc.subject.por.fl_str_mv |
Alveolar Bone Loss Periodontitis Bone Diseases |
topic |
Alveolar Bone Loss Periodontitis Bone Diseases |
description |
The purpose of this study was to morphometrically evaluate the influence of different durations of ovariectomy-induced estrogen deficiency on alveolar bone loss associated with ligature-induced bone loss in rats. Sixty female Wistar rats were randomly assigned to ovariectomy (OVX test group) or sham operation (SHAM control group). The OVX and SHAM groups were each distributed into three subgroups of ten rats each according to the duration of estrogen deficiency (30, 60 and 90 postoperative days). In all groups, for the last 30 days of the experimental period, cotton ligatures were placed around the cervix of the right upper second molar; the contralateral tooth was left unligated to serve as a control. The maxillary bones were removed, and the alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at the buccal site of the right upper second molar. A comparison between the ligated and unligated groups verified the presence of ligature-induced alveolar bone loss (p < 0.05). No significant differences were observed among the unligated groups (p > 0.05). A significant increase in bone loss was observed when ligation occurred 90 days after ovariectomy compared with the sham group (p < 0.05). These results demonstrate that long-term estrogen deficiency affects ligature-induced alveolar bone loss. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000600011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242011000600011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1806-83242011000600011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.25 n.6 2011 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318322509938688 |