Relationship between anemia and oral cancer: a case-control study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100265 |
Resumo: | Abstract The aim of this study was to investigate the occurrence, type and severity of anemia at the time of diagnosis of oral cancer, and its potential association with the degree of tumor cell differentiation. This case-control study used 366 medical records of patients treated at two referral centers for oral cancer diagnosis, specifically: cases (n=70) with a histopathological diagnosis of oral squamous cell carcinoma (OSCC) of the oral cavity, and controls (n=296) with benign oral lesions. Sociodemographic, behavioral, and clinical variables of both groups, as well as complete blood count values, were analyzed by descriptive statistics and crude/adjusted logistic regression. Anemia was detected in 15.7% of the cases and 11.8% of the controls. The presence of anemia had an OR=1.64 (odds ratio) (95%CI 0.54–5.00) for OSCC, with no significantly statistical association. Normocytic anemia was the most prevalent form of anemia when oral cancer was diagnosed (91.4% of the controls and 72.7% of the cases), and moderate to severely low hemoglobin levels were associated with OSCC diagnosis (OR 6.49; 95%CI 1.18–35.24), albeit data on hematological examinations were missing. |
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Relationship between anemia and oral cancer: a case-control studyAnemiaHemoglobinsMouth NeoplasmsDiagnosisCase-Control StudiesAbstract The aim of this study was to investigate the occurrence, type and severity of anemia at the time of diagnosis of oral cancer, and its potential association with the degree of tumor cell differentiation. This case-control study used 366 medical records of patients treated at two referral centers for oral cancer diagnosis, specifically: cases (n=70) with a histopathological diagnosis of oral squamous cell carcinoma (OSCC) of the oral cavity, and controls (n=296) with benign oral lesions. Sociodemographic, behavioral, and clinical variables of both groups, as well as complete blood count values, were analyzed by descriptive statistics and crude/adjusted logistic regression. Anemia was detected in 15.7% of the cases and 11.8% of the controls. The presence of anemia had an OR=1.64 (odds ratio) (95%CI 0.54–5.00) for OSCC, with no significantly statistical association. Normocytic anemia was the most prevalent form of anemia when oral cancer was diagnosed (91.4% of the controls and 72.7% of the cases), and moderate to severely low hemoglobin levels were associated with OSCC diagnosis (OR 6.49; 95%CI 1.18–35.24), albeit data on hematological examinations were missing.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100265Brazilian Oral Research v.35 2021reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107bor-2021.vol35.0085info:eu-repo/semantics/openAccessSGANZERLA,Juliana TomazKRUEGER,Gabriel FranciscoOLIVEIRA,Milene Castilhos deGASSEN,Humberto ThomaziSANTOS,Marcos André dosCELESTE,Roger KellerMIGUENS-JUNIOR,Sergio Augusto Quevedoeng2021-08-04T00:00:00Zoai:scielo:S1806-83242021000100265Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2021-08-04T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Relationship between anemia and oral cancer: a case-control study |
title |
Relationship between anemia and oral cancer: a case-control study |
spellingShingle |
Relationship between anemia and oral cancer: a case-control study SGANZERLA,Juliana Tomaz Anemia Hemoglobins Mouth Neoplasms Diagnosis Case-Control Studies |
title_short |
Relationship between anemia and oral cancer: a case-control study |
title_full |
Relationship between anemia and oral cancer: a case-control study |
title_fullStr |
Relationship between anemia and oral cancer: a case-control study |
title_full_unstemmed |
Relationship between anemia and oral cancer: a case-control study |
title_sort |
Relationship between anemia and oral cancer: a case-control study |
author |
SGANZERLA,Juliana Tomaz |
author_facet |
SGANZERLA,Juliana Tomaz KRUEGER,Gabriel Francisco OLIVEIRA,Milene Castilhos de GASSEN,Humberto Thomazi SANTOS,Marcos André dos CELESTE,Roger Keller MIGUENS-JUNIOR,Sergio Augusto Quevedo |
author_role |
author |
author2 |
KRUEGER,Gabriel Francisco OLIVEIRA,Milene Castilhos de GASSEN,Humberto Thomazi SANTOS,Marcos André dos CELESTE,Roger Keller MIGUENS-JUNIOR,Sergio Augusto Quevedo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
SGANZERLA,Juliana Tomaz KRUEGER,Gabriel Francisco OLIVEIRA,Milene Castilhos de GASSEN,Humberto Thomazi SANTOS,Marcos André dos CELESTE,Roger Keller MIGUENS-JUNIOR,Sergio Augusto Quevedo |
dc.subject.por.fl_str_mv |
Anemia Hemoglobins Mouth Neoplasms Diagnosis Case-Control Studies |
topic |
Anemia Hemoglobins Mouth Neoplasms Diagnosis Case-Control Studies |
description |
Abstract The aim of this study was to investigate the occurrence, type and severity of anemia at the time of diagnosis of oral cancer, and its potential association with the degree of tumor cell differentiation. This case-control study used 366 medical records of patients treated at two referral centers for oral cancer diagnosis, specifically: cases (n=70) with a histopathological diagnosis of oral squamous cell carcinoma (OSCC) of the oral cavity, and controls (n=296) with benign oral lesions. Sociodemographic, behavioral, and clinical variables of both groups, as well as complete blood count values, were analyzed by descriptive statistics and crude/adjusted logistic regression. Anemia was detected in 15.7% of the cases and 11.8% of the controls. The presence of anemia had an OR=1.64 (odds ratio) (95%CI 0.54–5.00) for OSCC, with no significantly statistical association. Normocytic anemia was the most prevalent form of anemia when oral cancer was diagnosed (91.4% of the controls and 72.7% of the cases), and moderate to severely low hemoglobin levels were associated with OSCC diagnosis (OR 6.49; 95%CI 1.18–35.24), albeit data on hematological examinations were missing. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100265 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100265 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1807-3107bor-2021.vol35.0085 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.35 2021 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318327650058240 |