Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Oral Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000200020 |
Resumo: | The aim of this study was to determine whether the plasma CTX bone remodeling marker is useful for indicating the bone metabolic activity level of the mandible. Thirty-six patients were selected; all were postmenopausal and aged 50 years or over. In accordance with the WHO criteria for osteoporosis, a control group was set up (n = 10) in which the T-score was greater than -1 and a diseased group with T-score less than -1. Using MDP-99mTc samples, the radioisotope uptake in the femoral neck (R2) and mandibular body (R1) was analyzed. A third examination was performed using the plasma CTX biochemical bone-modeling marker. The inferential results for the diseased group showed that Ln(R1) presented a statistically significant linear relationship with Ln(CTx) (p = 0.067) and with the T-score (p = 0.018). The plasma CTX bone remodeling marker is useful for monitoring the bone metabolic activity of the mandible. |
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Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patientsBiological markersBone diseases/metabolicMandibleThe aim of this study was to determine whether the plasma CTX bone remodeling marker is useful for indicating the bone metabolic activity level of the mandible. Thirty-six patients were selected; all were postmenopausal and aged 50 years or over. In accordance with the WHO criteria for osteoporosis, a control group was set up (n = 10) in which the T-score was greater than -1 and a diseased group with T-score less than -1. Using MDP-99mTc samples, the radioisotope uptake in the femoral neck (R2) and mandibular body (R1) was analyzed. A third examination was performed using the plasma CTX biochemical bone-modeling marker. The inferential results for the diseased group showed that Ln(R1) presented a statistically significant linear relationship with Ln(CTx) (p = 0.067) and with the T-score (p = 0.018). The plasma CTX bone remodeling marker is useful for monitoring the bone metabolic activity of the mandible.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2010-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000200020Brazilian Oral Research v.24 n.2 2010reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242010000200020info:eu-repo/semantics/openAccessAvolio,GlacioBrandão,CynthiaMarcucci,MarceloAlonso,Gilbertoeng2010-07-22T00:00:00Zoai:scielo:S1806-83242010000200020Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2010-07-22T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false |
dc.title.none.fl_str_mv |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
title |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
spellingShingle |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients Avolio,Glacio Biological markers Bone diseases/metabolic Mandible |
title_short |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
title_full |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
title_fullStr |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
title_full_unstemmed |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
title_sort |
Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients |
author |
Avolio,Glacio |
author_facet |
Avolio,Glacio Brandão,Cynthia Marcucci,Marcelo Alonso,Gilberto |
author_role |
author |
author2 |
Brandão,Cynthia Marcucci,Marcelo Alonso,Gilberto |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Avolio,Glacio Brandão,Cynthia Marcucci,Marcelo Alonso,Gilberto |
dc.subject.por.fl_str_mv |
Biological markers Bone diseases/metabolic Mandible |
topic |
Biological markers Bone diseases/metabolic Mandible |
description |
The aim of this study was to determine whether the plasma CTX bone remodeling marker is useful for indicating the bone metabolic activity level of the mandible. Thirty-six patients were selected; all were postmenopausal and aged 50 years or over. In accordance with the WHO criteria for osteoporosis, a control group was set up (n = 10) in which the T-score was greater than -1 and a diseased group with T-score less than -1. Using MDP-99mTc samples, the radioisotope uptake in the femoral neck (R2) and mandibular body (R1) was analyzed. A third examination was performed using the plasma CTX biochemical bone-modeling marker. The inferential results for the diseased group showed that Ln(R1) presented a statistically significant linear relationship with Ln(CTx) (p = 0.067) and with the T-score (p = 0.018). The plasma CTX bone remodeling marker is useful for monitoring the bone metabolic activity of the mandible. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000200020 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000200020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1806-83242010000200020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pesquisa Odontológica - SBPqO |
dc.source.none.fl_str_mv |
Brazilian Oral Research v.24 n.2 2010 reponame:Brazilian Oral Research instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO) instacron:SBPQO |
instname_str |
Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
instacron_str |
SBPQO |
institution |
SBPQO |
reponame_str |
Brazilian Oral Research |
collection |
Brazilian Oral Research |
repository.name.fl_str_mv |
Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO) |
repository.mail.fl_str_mv |
pob@edu.usp.br||bor@sbpqo.org.br |
_version_ |
1750318322050662400 |