Periodontal disease: a genetic perspective

Detalhes bibliográficos
Autor(a) principal: Taba Jr,Mario
Data de Publicação: 2012
Outros Autores: Souza,Sergio Luis Scombatti de, Mariguela,Viviane Casagrande
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242012000700006
Resumo: Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many studies have provided a valuable contribution to understanding the genetic basis of periodontal disease, but the specific candidate genes of susceptibility are still unknown. In fact, genome-wide studies and screening of single-nucleotide polymorphisms have yielded new genetic information without a definitive solution for the management of periodontal disease. In this manuscript, we provide an overview of the most relevant literature, presenting the main concepts and insights of the strategies that have been emerging to better diagnose and treat periodontal disease based on biomarker analysis and host modulation.
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spelling Periodontal disease: a genetic perspectivePeriodontitisGenetic Predisposition to DiseaseDiagnosisRisk FactorsPeriodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many studies have provided a valuable contribution to understanding the genetic basis of periodontal disease, but the specific candidate genes of susceptibility are still unknown. In fact, genome-wide studies and screening of single-nucleotide polymorphisms have yielded new genetic information without a definitive solution for the management of periodontal disease. In this manuscript, we provide an overview of the most relevant literature, presenting the main concepts and insights of the strategies that have been emerging to better diagnose and treat periodontal disease based on biomarker analysis and host modulation.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242012000700006Brazilian Oral Research v.26 n.spe1 2012reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242012000700006info:eu-repo/semantics/openAccessTaba Jr,MarioSouza,Sergio Luis Scombatti deMariguela,Viviane Casagrandeeng2013-01-10T00:00:00Zoai:scielo:S1806-83242012000700006Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2013-01-10T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Periodontal disease: a genetic perspective
title Periodontal disease: a genetic perspective
spellingShingle Periodontal disease: a genetic perspective
Taba Jr,Mario
Periodontitis
Genetic Predisposition to Disease
Diagnosis
Risk Factors
title_short Periodontal disease: a genetic perspective
title_full Periodontal disease: a genetic perspective
title_fullStr Periodontal disease: a genetic perspective
title_full_unstemmed Periodontal disease: a genetic perspective
title_sort Periodontal disease: a genetic perspective
author Taba Jr,Mario
author_facet Taba Jr,Mario
Souza,Sergio Luis Scombatti de
Mariguela,Viviane Casagrande
author_role author
author2 Souza,Sergio Luis Scombatti de
Mariguela,Viviane Casagrande
author2_role author
author
dc.contributor.author.fl_str_mv Taba Jr,Mario
Souza,Sergio Luis Scombatti de
Mariguela,Viviane Casagrande
dc.subject.por.fl_str_mv Periodontitis
Genetic Predisposition to Disease
Diagnosis
Risk Factors
topic Periodontitis
Genetic Predisposition to Disease
Diagnosis
Risk Factors
description Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many studies have provided a valuable contribution to understanding the genetic basis of periodontal disease, but the specific candidate genes of susceptibility are still unknown. In fact, genome-wide studies and screening of single-nucleotide polymorphisms have yielded new genetic information without a definitive solution for the management of periodontal disease. In this manuscript, we provide an overview of the most relevant literature, presenting the main concepts and insights of the strategies that have been emerging to better diagnose and treat periodontal disease based on biomarker analysis and host modulation.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242012000700006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242012000700006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242012000700006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.26 n.spe1 2012
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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