Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors

Detalhes bibliográficos
Autor(a) principal: Ito,Fabio Augusto
Data de Publicação: 2009
Outros Autores: Ito,Kazuhiro, Coletta,Ricardo Della, Vargas,Pablo Agustín, Lopes,Márcio Ajudarte
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000400008
Resumo: The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands. A total of 41 pleomorphic adenomas, 30 Warthin's tumors, 30 mucoepidermoid carcinomas and 30 adenoid cystic carcinomas were analyzed, and the immunohistochemical expression of these hormone receptors were assessed. It was observed that all cases were negative for estrogen and progesterone receptors. Androgen receptor was positive in 2 cases each of pleomorphic adenoma, mucoepidermoid carcinoma and adenoid cystic carcinoma. In conclusion, the results do not support a role of estrogen and progesterone in the tumorigenesis of pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas. However, androgen receptors can play a role in a small set of salivary gland tumors, and this would deserve further studies.
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spelling Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumorsReceptors, androgenReceptors, estrogenReceptors, progesteroneSalivary gland neoplasmsThe aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands. A total of 41 pleomorphic adenomas, 30 Warthin's tumors, 30 mucoepidermoid carcinomas and 30 adenoid cystic carcinomas were analyzed, and the immunohistochemical expression of these hormone receptors were assessed. It was observed that all cases were negative for estrogen and progesterone receptors. Androgen receptor was positive in 2 cases each of pleomorphic adenoma, mucoepidermoid carcinoma and adenoid cystic carcinoma. In conclusion, the results do not support a role of estrogen and progesterone in the tumorigenesis of pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas. However, androgen receptors can play a role in a small set of salivary gland tumors, and this would deserve further studies.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2009-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000400008Brazilian Oral Research v.23 n.4 2009reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242009000400008info:eu-repo/semantics/openAccessIto,Fabio AugustoIto,KazuhiroColetta,Ricardo DellaVargas,Pablo AgustínLopes,Márcio Ajudarteeng2009-12-15T00:00:00Zoai:scielo:S1806-83242009000400008Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2009-12-15T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
title Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
spellingShingle Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
Ito,Fabio Augusto
Receptors, androgen
Receptors, estrogen
Receptors, progesterone
Salivary gland neoplasms
title_short Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
title_full Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
title_fullStr Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
title_full_unstemmed Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
title_sort Immunohistochemical study of androgen, estrogen and progesterone receptors in salivary gland tumors
author Ito,Fabio Augusto
author_facet Ito,Fabio Augusto
Ito,Kazuhiro
Coletta,Ricardo Della
Vargas,Pablo Agustín
Lopes,Márcio Ajudarte
author_role author
author2 Ito,Kazuhiro
Coletta,Ricardo Della
Vargas,Pablo Agustín
Lopes,Márcio Ajudarte
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ito,Fabio Augusto
Ito,Kazuhiro
Coletta,Ricardo Della
Vargas,Pablo Agustín
Lopes,Márcio Ajudarte
dc.subject.por.fl_str_mv Receptors, androgen
Receptors, estrogen
Receptors, progesterone
Salivary gland neoplasms
topic Receptors, androgen
Receptors, estrogen
Receptors, progesterone
Salivary gland neoplasms
description The aim of this work was to study the immunohistochemical expression of androgen receptor, estrogen receptor and progesterone receptor in pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas of salivary glands. A total of 41 pleomorphic adenomas, 30 Warthin's tumors, 30 mucoepidermoid carcinomas and 30 adenoid cystic carcinomas were analyzed, and the immunohistochemical expression of these hormone receptors were assessed. It was observed that all cases were negative for estrogen and progesterone receptors. Androgen receptor was positive in 2 cases each of pleomorphic adenoma, mucoepidermoid carcinoma and adenoid cystic carcinoma. In conclusion, the results do not support a role of estrogen and progesterone in the tumorigenesis of pleomorphic adenomas, Warthin's tumors, mucoepidermoid carcinomas and adenoid cystic carcinomas. However, androgen receptors can play a role in a small set of salivary gland tumors, and this would deserve further studies.
publishDate 2009
dc.date.none.fl_str_mv 2009-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000400008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000400008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242009000400008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.23 n.4 2009
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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