In situ effect of titanium tetrafluoride varnish on enamel demineralization

Bibliographic Details
Main Author: ALEXANDRIA,Adílis Kalina
Publication Date: 2017
Other Authors: NASSUR,Camila, NÓBREGA,Carolina Bezerra Cavalcanti, VALENÇA,Ana Maria Gondim, ROSALEN,Pedro Luiz, MAIA,Lucianne Cople
Format: Article
Language: eng
Source: Brazilian Oral Research
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100271
Summary: Abstract The effect of a 4% titanium tetrafluoride (TiF 4 ) varnish on enamel demineralization was evaluated. Twelve volunteers participated in this double-blind, randomized crossover study. Six enamel specimens were positioned in intraoral appliances throughout four treatment stages: 4% TiF 4 varnish (experimental varnish), 5% sodium fluoride (NaF) varnish (Duraphat ® ), placebo varnish, and negative control (deionized water). After 24 h, the varnishes were removed and plaques were allowed to accumulate. A 20% sucrose solution was dripped onto enamel blocks (10x/day). Enamel alterations were analyzed by surface microhardness (SMH), percentage of surface loss (%SML), cross-sectional microhardness (CSMH), scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDS). Student’s paired t-test was used for SMH analysis and repeated-measures analysis of variance (ANOVA) for %SML and CSMH (∆Z) analyses (p-value=0.05). The TiF 4 varnish group had lower %SML than the placebo and control groups (p=0.044 and p=0.003, respectively), thus showing its capacity to inhibit surface demineralization. TiF 4 and NaF varnishes demonstrated a protective effect against mineral loss on the enamel subsurface. Both were statistically different from the control group when CSMH was analyzed (p=0.000). A titanium dioxide film was observed on enamel surfaces of the TiF 4 group SEM images. EDS confirmed the presence of titanium in all TiF 4 samples. The 4% TiF 4 varnish is a promising compound capable of reacting with enamel to protect it against surface and subsurface demineralization.
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spelling In situ effect of titanium tetrafluoride varnish on enamel demineralizationFluoridesTooth DemineralizationBiofilmsAbstract The effect of a 4% titanium tetrafluoride (TiF 4 ) varnish on enamel demineralization was evaluated. Twelve volunteers participated in this double-blind, randomized crossover study. Six enamel specimens were positioned in intraoral appliances throughout four treatment stages: 4% TiF 4 varnish (experimental varnish), 5% sodium fluoride (NaF) varnish (Duraphat ® ), placebo varnish, and negative control (deionized water). After 24 h, the varnishes were removed and plaques were allowed to accumulate. A 20% sucrose solution was dripped onto enamel blocks (10x/day). Enamel alterations were analyzed by surface microhardness (SMH), percentage of surface loss (%SML), cross-sectional microhardness (CSMH), scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDS). Student’s paired t-test was used for SMH analysis and repeated-measures analysis of variance (ANOVA) for %SML and CSMH (∆Z) analyses (p-value=0.05). The TiF 4 varnish group had lower %SML than the placebo and control groups (p=0.044 and p=0.003, respectively), thus showing its capacity to inhibit surface demineralization. TiF 4 and NaF varnishes demonstrated a protective effect against mineral loss on the enamel subsurface. Both were statistically different from the control group when CSMH was analyzed (p=0.000). A titanium dioxide film was observed on enamel surfaces of the TiF 4 group SEM images. EDS confirmed the presence of titanium in all TiF 4 samples. The 4% TiF 4 varnish is a promising compound capable of reacting with enamel to protect it against surface and subsurface demineralization.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100271Brazilian Oral Research v.31 2017reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107bor-2017.vol31.0086info:eu-repo/semantics/openAccessALEXANDRIA,Adílis KalinaNASSUR,CamilaNÓBREGA,Carolina Bezerra CavalcantiVALENÇA,Ana Maria GondimROSALEN,Pedro LuizMAIA,Lucianne Copleeng2017-10-31T00:00:00Zoai:scielo:S1806-83242017000100271Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2017-10-31T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv In situ effect of titanium tetrafluoride varnish on enamel demineralization
title In situ effect of titanium tetrafluoride varnish on enamel demineralization
spellingShingle In situ effect of titanium tetrafluoride varnish on enamel demineralization
ALEXANDRIA,Adílis Kalina
Fluorides
Tooth Demineralization
Biofilms
title_short In situ effect of titanium tetrafluoride varnish on enamel demineralization
title_full In situ effect of titanium tetrafluoride varnish on enamel demineralization
title_fullStr In situ effect of titanium tetrafluoride varnish on enamel demineralization
title_full_unstemmed In situ effect of titanium tetrafluoride varnish on enamel demineralization
title_sort In situ effect of titanium tetrafluoride varnish on enamel demineralization
author ALEXANDRIA,Adílis Kalina
author_facet ALEXANDRIA,Adílis Kalina
NASSUR,Camila
NÓBREGA,Carolina Bezerra Cavalcanti
VALENÇA,Ana Maria Gondim
ROSALEN,Pedro Luiz
MAIA,Lucianne Cople
author_role author
author2 NASSUR,Camila
NÓBREGA,Carolina Bezerra Cavalcanti
VALENÇA,Ana Maria Gondim
ROSALEN,Pedro Luiz
MAIA,Lucianne Cople
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv ALEXANDRIA,Adílis Kalina
NASSUR,Camila
NÓBREGA,Carolina Bezerra Cavalcanti
VALENÇA,Ana Maria Gondim
ROSALEN,Pedro Luiz
MAIA,Lucianne Cople
dc.subject.por.fl_str_mv Fluorides
Tooth Demineralization
Biofilms
topic Fluorides
Tooth Demineralization
Biofilms
description Abstract The effect of a 4% titanium tetrafluoride (TiF 4 ) varnish on enamel demineralization was evaluated. Twelve volunteers participated in this double-blind, randomized crossover study. Six enamel specimens were positioned in intraoral appliances throughout four treatment stages: 4% TiF 4 varnish (experimental varnish), 5% sodium fluoride (NaF) varnish (Duraphat ® ), placebo varnish, and negative control (deionized water). After 24 h, the varnishes were removed and plaques were allowed to accumulate. A 20% sucrose solution was dripped onto enamel blocks (10x/day). Enamel alterations were analyzed by surface microhardness (SMH), percentage of surface loss (%SML), cross-sectional microhardness (CSMH), scanning electron microscopy (SEM), and energy dispersive X-ray spectrometry (EDS). Student’s paired t-test was used for SMH analysis and repeated-measures analysis of variance (ANOVA) for %SML and CSMH (∆Z) analyses (p-value=0.05). The TiF 4 varnish group had lower %SML than the placebo and control groups (p=0.044 and p=0.003, respectively), thus showing its capacity to inhibit surface demineralization. TiF 4 and NaF varnishes demonstrated a protective effect against mineral loss on the enamel subsurface. Both were statistically different from the control group when CSMH was analyzed (p=0.000). A titanium dioxide film was observed on enamel surfaces of the TiF 4 group SEM images. EDS confirmed the presence of titanium in all TiF 4 samples. The 4% TiF 4 varnish is a promising compound capable of reacting with enamel to protect it against surface and subsurface demineralization.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100271
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242017000100271
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1807-3107bor-2017.vol31.0086
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.31 2017
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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